@kevinbarrydinneen.bsky.social
“We are concerned that some psychiatrists tend to minimise the adverse effects associated with antidepressants, particularly their dependence-inducing effects,” said Professor Moncrieff, a professor of critical and social psychiatry.
A study has cast doubt on the widely cited claim that antidepressant drugs such as SSRIs have few withdrawal symptoms, revealing that pharmaceutical industry funding could be skewing data to minimise adverse effects.
Antidepressant drug withdrawals may affect more than half of all users - leafie
A study has cast doubt on the widely cited claim that antidepressant drugs such as SSRIs have few withdrawal symptoms, revealing that pharmaceutical industry funding could be skewing data to minimise adverse effects.
www.leafie.co.uk
August 29, 2025 at 7:33 AM
“We are concerned that some psychiatrists tend to minimise the adverse effects associated with antidepressants, particularly their dependence-inducing effects,” said Professor Moncrieff, a professor of critical and social psychiatry.
“Notably, the research team found that cannabis users exhibited superior performance across multiple cognitive tests compared to non-users. The effects of cannabis use and improved cognition appeared concurrently across various brain systems.”
Study of over 25,000 people found that people who used cannabis performed better in cognitive tests than non-users.
www.leafie.co.uk/new...
www.leafie.co.uk/new...
Cannabis use may reverse cognitive ageing, study finds - leafie
Study of over 25,000 people found that people who used cannabis performed better in cognitive tests than non users.
www.leafie.co.uk
August 27, 2025 at 7:58 AM
“Notably, the research team found that cannabis users exhibited superior performance across multiple cognitive tests compared to non-users. The effects of cannabis use and improved cognition appeared concurrently across various brain systems.”
“Of particular interest were 16 compounds tentatively identified as flavoalkaloids – extremely rare compounds in nature known for their anti-inflammatory, anti-carcinogenic, and antioxidant properties.”
Researchers have found a number of rare compounds called flavoalkaloids in cannabis leaves for the first time, suggesting that plant material traditionally discarded during processing could contain valuable compounds for future medical applications.
Cannabis leaves found to contain rare compounds with potential medical benefits - leafie
Using a unique method of analysis, a team of researchers found a number of rare compounds called flavoalkaloids in cannabis leaves for the first time, suggesting that plant material traditionally discarded during processing could contain valuable compounds for future medical applications.
www.leafie.co.uk
August 26, 2025 at 7:41 AM
“Of particular interest were 16 compounds tentatively identified as flavoalkaloids – extremely rare compounds in nature known for their anti-inflammatory, anti-carcinogenic, and antioxidant properties.”
Issue 2 - OUT NOW!
We’ve toiled away at issue 2 for around 8 months, slight longer than expected but you can’t rush this level of quality!
Grab a copy before they sell out, we won’t be printing any more.
We’ve toiled away at issue 2 for around 8 months, slight longer than expected but you can’t rush this level of quality!
Grab a copy before they sell out, we won’t be printing any more.
The latest issue of our groundbreaking print magazine is out now.
Once again, we’ve packed the pages with untold stories from the worlds of cannabis, psychedelics and culture.
Grab your copy today: www.leafie.co.uk/pro...
Once again, we’ve packed the pages with untold stories from the worlds of cannabis, psychedelics and culture.
Grab your copy today: www.leafie.co.uk/pro...
The leafie Magazine – Issue 02 – leafie
Issue 02 of leafie's groundbreaking magazine covering untold stories across cannabis, psychedelics and culture.
www.leafie.co.uk
July 30, 2025 at 4:57 PM
Issue 2 - OUT NOW!
We’ve toiled away at issue 2 for around 8 months, slight longer than expected but you can’t rush this level of quality!
Grab a copy before they sell out, we won’t be printing any more.
We’ve toiled away at issue 2 for around 8 months, slight longer than expected but you can’t rush this level of quality!
Grab a copy before they sell out, we won’t be printing any more.
“In most cases, it is simply not possible for producers and sellers who operate outside of the realm of the law to match the safety and production standards followed by the often large companies that do things legally, leading to better quality and higher safety standards all around.”
From Uruguay to Czechia, people are now lighting up without fear of persecution. But it isn’t just consumers who are benefiting from the liberation of drug laws – decades of data show that everyone benefits from cannabis reform.
www.leafie.co.uk/can...
www.leafie.co.uk/can...
7 ways cannabis legalisation has improved society across the world - leafie
From Uruguay to Czechia, people are now lighting up without fear of persecution. But it isn’t just consumers who are benefiting from the liberation of drug laws – decades of data show that everyone benefits from cannabis reform.
www.leafie.co.uk
July 24, 2025 at 7:03 AM
“In most cases, it is simply not possible for producers and sellers who operate outside of the realm of the law to match the safety and production standards followed by the often large companies that do things legally, leading to better quality and higher safety standards all around.”
“The Loop’s work has proved vital in identifying dangerous substances. At Parklife in June 2025, the charity’s onsite testing identified high and variable strength MDMA pills containing up to three times a common adult dose, enabling rapid public alerts about overdose risks.”
The Loop, the UK’s only dedicated drug testing charity, has launched a £25,000 fundraising campaign to expand its harm reduction services.
www.leafie.co.uk/new...
www.leafie.co.uk/new...
UK drug checking charity The Loop launches fundraising campaign - leafie
The Loop, the UK’s only dedicated drug testing charity, has launched a £25,000 fundraising campaign to expand its harm reduction services.
www.leafie.co.uk
July 23, 2025 at 8:20 AM
“The Loop’s work has proved vital in identifying dangerous substances. At Parklife in June 2025, the charity’s onsite testing identified high and variable strength MDMA pills containing up to three times a common adult dose, enabling rapid public alerts about overdose risks.”
“The study represents the first experimental evidence that psilocybin can combat ageing processes at the cellular level, potentially opening new avenues for anti-ageing therapies in humans.”
The study provides preclinical evidence that psilocybin can extend the life of mice and of cells of lab-grown human tissue, which could lead to it being used as a treatment to improve both quality of life and longevity.
www.leafie.co.uk/new...
www.leafie.co.uk/new...
Psilocybin could combat ageing, study finds - leafie
The study provides preclinical evidence that psilocybin can extend the life of mice and of cells of lab-grown human tissue, which could lead to it being used as a treatment to improve both quality of life and longevity.
www.leafie.co.uk
July 14, 2025 at 7:25 AM
“The study represents the first experimental evidence that psilocybin can combat ageing processes at the cellular level, potentially opening new avenues for anti-ageing therapies in humans.”
These all reiterate the company’s promises to investors to “use state of the art technology to bring the popular drug to the masses”, alongside an enticing pricing structure, offering “margins for sellers ranging from 50–70%… for every $100 the holder sells, they keep up to $70 of it.”
Dr Green, a blockchain project promoted by a man who styles himself the world’s first “cannabis billionaire", has been promising potential investors lucrative returns in the cannabis industry.
But do the bold claims stack up to the facts?
www.leafie.co.uk/can...
But do the bold claims stack up to the facts?
www.leafie.co.uk/can...
Dr Green Digital Key: The claims, the concerns, and why we’re investigating - leafie
Dr Green NFT – a high-profile blockchain project promoted by a man who styles himself the world’s first “cannabis billionaire" – has been promising potential investors lucrative returns in the medical cannabis industry. An investigation by leafie in conjunction with other leading publications has found concerning differences between the company’s…
www.leafie.co.uk
July 8, 2025 at 8:07 AM
These all reiterate the company’s promises to investors to “use state of the art technology to bring the popular drug to the masses”, alongside an enticing pricing structure, offering “margins for sellers ranging from 50–70%… for every $100 the holder sells, they keep up to $70 of it.”
There’s no need for a black/legacy market if everybody is given the same opportunity to be involved in a legal one.
But, if licenses for growing and selling are only given to big companies who only want to profit from us, then what’s the point?
But, if licenses for growing and selling are only given to big companies who only want to profit from us, then what’s the point?
Low prices and improved access mean 80% of cannabis sales now happen through legitimate channels in Canada.
www.leafie.co.uk/new...
www.leafie.co.uk/new...
Legal cannabis has almost eliminated the black market in Canada - leafie
Low prices and improved access mean 80% of cannabis sales now happen through legitimate channels in Canada.
www.leafie.co.uk
May 19, 2025 at 8:36 AM
There’s no need for a black/legacy market if everybody is given the same opportunity to be involved in a legal one.
But, if licenses for growing and selling are only given to big companies who only want to profit from us, then what’s the point?
But, if licenses for growing and selling are only given to big companies who only want to profit from us, then what’s the point?
Make sure you read up on the rules and regs before you get on your flight - you don’t want a situation where you find yourself in trouble for a technicality that could have easily been avoided.
Starting to make plans for your summer holiday? You may be wondering how to legally and safely take your medical cannabis prescription with you.
We've updated our guide to travelling with your prescription to make it easier than ever.
www.leafie.co.uk/can...
We've updated our guide to travelling with your prescription to make it easier than ever.
www.leafie.co.uk/can...
How to travel abroad with a medical cannabis prescription - leafie
Planning a holiday or trip abroad? You may be wondering how to legally and safely take your medical cannabis prescription with you. Our handy guide will help you follow the proper procedures.
www.leafie.co.uk
May 12, 2025 at 6:54 AM
Make sure you read up on the rules and regs before you get on your flight - you don’t want a situation where you find yourself in trouble for a technicality that could have easily been avoided.
The mechanics behind this are fascinating.
Psychedelic drugs may improve mental health by dampening inflammation in the brain, according to a groundbreaking new study.
www.leafie.co.uk/new...
www.leafie.co.uk/new...
Psychedelics may improve mental health by reducing brain inflammation
The Harvard study identified a key anti-inflammatory mechanism behind psychedelic use which may explain the powerful results from these drugs.
www.leafie.co.uk
May 7, 2025 at 8:59 PM
The mechanics behind this are fascinating.
This is a remarkable study.
South Korean researchers identified a previously unknown cannabinoid called cannabielsoxa alongside several compounds that can inhibit neuroblastoma cancer cell growth.
www.leafie.co.uk/new...
www.leafie.co.uk/new...
New cannabinoid discovered during search for anti-cancer compounds - leafie
South Korean researchers identified a previously unknown cannabinoid called cannabielsoxa alongside several compounds that can inhibit neuroblastoma cancer cell growth.
www.leafie.co.uk
May 6, 2025 at 10:39 AM
This is a remarkable study.
“Stop and search rules also have particular significance for the estimated 60,000 to 80,000 people in the UK who have prescriptions for medical cannabis, following its legalisation for medicinal use in November 2018.”
The force has been told to stop using the smell of cannabis as the sole justification for stop and search, following a recommendation from an independent panel, echoing national guidance from the IOPC.
www.leafie.co.uk/new...
www.leafie.co.uk/new...
Stop using cannabis for stop and search, Avon and Somerset Police told - leafie
The force has been told to stop using the smell of cannabis as the sole justification for stop and search, following a recommendation from an independent panel, echoing national guidance from the IOPC.
www.leafie.co.uk
April 30, 2025 at 10:48 AM
“Stop and search rules also have particular significance for the estimated 60,000 to 80,000 people in the UK who have prescriptions for medical cannabis, following its legalisation for medicinal use in November 2018.”
Did you know that there are more than 1 million medical cannabis patients in Australia? There are only 26.5 million, so 1 in 26 people are prescribed cannabis. The UK needs to catch up!
A 12-month study of Australian patients who were prescribed cannabis oil has shown that the benefits to health-related quality of life could be long-lasting.
www.leafie.co.uk/new...
www.leafie.co.uk/new...
Medical cannabis linked to long-term benefits in health - leafie
A 12 month study of Australian patients who were prescribed cannabis has shown that the benefits to health-related quality of life could be long-lasting.
www.leafie.co.uk
April 8, 2025 at 7:31 AM
Did you know that there are more than 1 million medical cannabis patients in Australia? There are only 26.5 million, so 1 in 26 people are prescribed cannabis. The UK needs to catch up!
There is stacks of evidence to suggest cannabis was used extensively by women throughout history for purposes associated with pregnancy and childbirth.
The study of nearly 1,500 mother-child pairs found no significant cognitive or developmental differences in two-year-olds whose mothers used cannabis while pregnant.
www.leafie.co.uk/new...
www.leafie.co.uk/new...
Prenatal cannabis use does not impact early-years child development, study finds - leafie
The study of nearly 1,500 mother-child pairs found no significant cognitive or developmental differences in two-year-olds whose mothers used cannabis while pregnant.
www.leafie.co.uk
April 4, 2025 at 6:37 AM
There is stacks of evidence to suggest cannabis was used extensively by women throughout history for purposes associated with pregnancy and childbirth.
Wow, I thought teens were taking it easy these days!
Experiencing negative consequences from drinking does not significantly reduce teenagers' willingness to continue consuming alcohol, a UK study has shown.
www.leafie.co.uk/new...
www.leafie.co.uk/new...
Teens undeterred by alcohol's negative effects, UK study finds - leafie
Experiencing negative consequences from drinking does not significantly reduce teenagers' willingness to continue consuming alcohol, challenging conventional harm-reduction approaches.
www.leafie.co.uk
April 3, 2025 at 6:43 AM
Wow, I thought teens were taking it easy these days!
Did you know that you can be prescribed cannabis edibles containing THC here in the UK?
The effects of cannabis edibles are notoriously stronger than smoking or vaporising, creating a much more intense and longer-lasting high.
Why does eating weed get us so stoned?
www.leafie.co.uk/art...
Why does eating weed get us so stoned?
www.leafie.co.uk/art...
Why are cannabis edibles so strong? - leafie
The effects of cannabis edibles are notoriously stronger than smoking or vaporising, but why does eating weed get us so high?
www.leafie.co.uk
April 2, 2025 at 6:55 AM
Did you know that you can be prescribed cannabis edibles containing THC here in the UK?
I like the way the Swiss are going about their cannabis business.
The Weed-Care pilot has shown that participants who were given access to legally obtainable cannabis for the ‘purpose of pleasure’ reported better mental health outcomes.
www.leafie.co.uk/new...
www.leafie.co.uk/new...
Swiss recreational cannabis trial shows positive mental health results - leafie
The Weed-Care pilot has shown that participants who were given access to legally obtainable cannabis for the ‘purpose of pleasure’ reported better mental health outcomes.
www.leafie.co.uk
March 31, 2025 at 7:58 PM
I like the way the Swiss are going about their cannabis business.
The rise in ketamine use seems a bit steep to me.
Government analysis of wastewater samples has found a sharp increase in ketamine, MDMA and cocaine use in England.
www.leafie.co.uk/new...
www.leafie.co.uk/new...
Party drug consumption up in England, wastewater study finds - leafie
Government analysis of wastewater samples has found a sharp increase in ketamine, MDMA and cocaine use in England
www.leafie.co.uk
March 20, 2025 at 7:40 AM
The rise in ketamine use seems a bit steep to me.
Decriminalisation didn’t turn cannabis consumers into violent offenders, not only that, it turns out that the police were able to spend more time actually policing.
Who would have thought?
Who would have thought?
After decriminalising cannabis in 2017, the US city of Atlanta saw a 20% reduction in violent crime as police could concentrate on more serious offences.
www.leafie.co.uk/new...
www.leafie.co.uk/new...
Violent crime fell 20% after cannabis decriminalisation - leafie
After decriminalising cannabis in 2017, the US city of Atlanta saw a 20% reduction in violent crime as police could concentrate on more serious offences.
www.leafie.co.uk
March 19, 2025 at 7:38 AM
Decriminalisation didn’t turn cannabis consumers into violent offenders, not only that, it turns out that the police were able to spend more time actually policing.
Who would have thought?
Who would have thought?
Seems like it’s bureaucracy getting the way again.
A survey of 250 practicing UK doctors has revealed that most would be willing to prescribe medical cannabis to manage chronic pain if it were part of the NHS toolkit.
www.leafie.co.uk/new...
www.leafie.co.uk/new...
UK doctors would prescribe cannabis if NHS allowed it - leafie
A survey of 250 practicing UK doctors has revealed that most would be willing to prescribe medical cannabis to manage chronic pain if it were part of the NHS toolkit.
www.leafie.co.uk
March 10, 2025 at 10:36 PM
Seems like it’s bureaucracy getting the way again.
Who would like to see a wider variety of cultivars available on the UK medicinal market?
Cali strains are dominating the cannabis world right now, from your local shottas menu to the formularies of clinics. Is the UK medical cannabis industry meeting the needs of patients with these strains, or are they putting profit above all else?
www.leafie.co.uk/art...
www.leafie.co.uk/art...
Is the UK medical cannabis industry too reliant on American genetics? - leafie
Cali strains are dominating the cannabis world right now, from your local shottas menu to the formularies of clinics. Is the UK medical cannabis industry meeting the needs of patients with these strains, or are they putting profit above all else?
www.leafie.co.uk
February 28, 2025 at 8:45 AM
Who would like to see a wider variety of cultivars available on the UK medicinal market?
This is something that me and my family know well. Using things to help take the edge of life and assist you to be a better parent, especially at the moment, is in my view, highly commendable.
A government-funded study has found mothers report being present and patient with their children with the help of cannabis, helping them to cope better with the stresses of parenthood.
www.leafie.co.uk/new...
www.leafie.co.uk/new...
Cannabis helps mothers be more positive parents, study finds - leafie
A government-funded study has found mothers report being present and patient with their children with the help of cannabis, helping them to cope better with the stresses of parenthood
www.leafie.co.uk
February 25, 2025 at 7:33 AM
This is something that me and my family know well. Using things to help take the edge of life and assist you to be a better parent, especially at the moment, is in my view, highly commendable.
What a feeling that must be, from no chance of parole to being out on the streets. I never thought I would say this, but, Go Donald!
On his first day in office, President Trump has pardoned Ross Ulbricht, aka Dread Pirate Roberts, founder of the darknet marketplace Silk Road.
Ulbricht has served 11 years of his double life plus 40-year sentence.
www.leafie.co.uk/new...
Ulbricht has served 11 years of his double life plus 40-year sentence.
www.leafie.co.uk/new...
Silk Road Founder Ross Ulbricht released from prison after Trump pardon - leafie
On his first day in office President Trump has pardoned Ross Ulbricht, aka Dread Pirate Roberts, founder of the darknet marketplace Silk Road. Ulbricht has served 11 years of his double life plus 40-year sentence.
www.leafie.co.uk
January 22, 2025 at 2:36 PM
What a feeling that must be, from no chance of parole to being out on the streets. I never thought I would say this, but, Go Donald!