Really excited to be part of these Research Talks at @ucf.bsky.social Will be sharing some stories 🙂: "From Protein Domains to Cancer Subtypes: Harnessing the Power of Classification Algorithms to Advance Biology" #UCF #computerscience #bioinformatics #computationalbiology

DrugDomain 2.0 (drugdomain.cs.ucf.edu) paper is out @csbj.org: doi.org/10.1016/j.cs... The new version of DB is an updated comprehensive resource, that extends earlier releases by linking evolutionary domain classifications to ligand binding events across the entire Protein Data Bank #bioinformatics

DrugDomain v2.0 is out - drugdomain.cs.ucf.edu The database reports the interactions of structural protein domains with a wide array of small organic (including drugs) and inorganic compounds, covering the full breadth of the Protein Data Bank. doi.org/10.1101/2025... #drugdiscovery #alphafold

Thrilled to share that I'll be joining @ucf.bsky.social as an Assistant Professor.
Medvedev Lab (medvedev-lab.cs.ucf.edu) will open in August 2025. Our work will address critical biological questions in Structural and Cancer Biology. Stay tuned 😉

We used AI to study how post-translational modifications (PTMs) affect drug binding and protein structure. Using AF3, RFAA and Chai-1, we generated > 14,000 models with > 6,000 of ligand-related PTMs. Paper is out in J. of Chemoinformatics rdcu.be/ekFlo #drugdiscovery #alphafold #bioinformatics #AI

Excited to share my recent research related to interactions between small molecule drugs and protein domains. @biophysicalsoc.bsky.social #bps2025 #computationalbiology #bioinformatics #drugdiscovery

📜 Our new preprint is out: www.biorxiv.org/content/10.1...

💡 We explored the role of post-translational modifications (PTMs) in modulating drug binding, with a focus on understanding the structural consequences of PTMs using advanced AI methods.