@ksumigray.bsky.social
Reposted
💡 Cancer cells don’t just mutate—they reorganize their DNA in 3D space.
Our new study shows how the genome’s folding pattern shifts as tumors progress, cell by cell 🧩🧬.
It’s the first 3D genome atlas of cancer progression.
Thread 👇
Our new study shows how the genome’s folding pattern shifts as tumors progress, cell by cell 🧩🧬.
It’s the first 3D genome atlas of cancer progression.
Thread 👇
August 26, 2025 at 1:20 PM
💡 Cancer cells don’t just mutate—they reorganize their DNA in 3D space.
Our new study shows how the genome’s folding pattern shifts as tumors progress, cell by cell 🧩🧬.
It’s the first 3D genome atlas of cancer progression.
Thread 👇
Our new study shows how the genome’s folding pattern shifts as tumors progress, cell by cell 🧩🧬.
It’s the first 3D genome atlas of cancer progression.
Thread 👇
Villi maximize absorptive surface area in the gut. By using mulitcolor lineage reporters (magenta and yellow), we've been watching cells march up the villus to their ultimate death when they reach the top.
August 26, 2025 at 6:05 PM
Villi maximize absorptive surface area in the gut. By using mulitcolor lineage reporters (magenta and yellow), we've been watching cells march up the villus to their ultimate death when they reach the top.
Caco2 cells are human colon adenomacarcinoma cell line - we love them for their robust junction formation and cute microvilli (phalloidin labeling stains F-actin here!). In collaborations with some friends, we are investigating novel regulatory mechanisms of junctional integrity & barrier function
July 9, 2025 at 12:07 PM
Caco2 cells are human colon adenomacarcinoma cell line - we love them for their robust junction formation and cute microvilli (phalloidin labeling stains F-actin here!). In collaborations with some friends, we are investigating novel regulatory mechanisms of junctional integrity & barrier function
Science is pretty yall
June 27, 2025 at 6:42 PM
Science is pretty yall