Kurt
@kurtprins.bsky.social
42 followers
39 following
12 posts
Husband, father, physician-scientists who loves metabolism, cytoskeleton, inflammation, and organ crosstalk
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Kurt
@kurtprins.bsky.social
· May 16
Lactobacillus Restructures the Micro/Mycobiome to Combat Inflammation-Mediated Right Ventricular Dysfunction in Pulmonary Arterial Hypertension | Circulation: Heart Failure
BACKGROUND: Inflammation suppresses right ventricular (RV) function in pulmonary arterial hypertension
(PAH). In particular, we showed GP130 (glycoprotein-130) signaling promotes pathological
microtub...
www.ahajournals.org
Kurt
@kurtprins.bsky.social
· Mar 29
Proteomic and Metabolomic Profiling Nominates Druggable Targets and Biomarkers for Pulmonary Arterial Hypertension-Associated Myopathy and Exercise Intolerance
Background: Pulmonary arterial hypertension (PAH) is a rare but debilitating condition that causes exercise intolerance and ultimately death. Skeletal muscle derangements contribute to depressed exerc...
www.biorxiv.org
Reposted by Kurt
Kurt
@kurtprins.bsky.social
· Mar 8
Reposted by Kurt
Kurt
@kurtprins.bsky.social
· Nov 11
Ferroptosis-Mediated Inflammation Promotes Pulmonary Hypertension | Circulation Research
BACKGROUND: Mitochondrial dysfunction, characterized by impaired lipid metabolism and heightened
reactive oxygen species generation, results in lipid peroxidation and ferroptosis.
Ferroptosis is an in...
www.ahajournals.org