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Yuval Nir
@labnir.bsky.social
· 13d
Arousal as a universal embedding for spatiotemporal brain dynamics - Nature
Reframing of arousal as a latent dynamical system can reconstruct multidimensional measurements of large-scale spatiotemporal brain dynamics on the timescale of seconds in mice.
www.nature.com
Reposted by Yuval Nir
Yuval Nir
@labnir.bsky.social
· 27d
Yuval Nir
@labnir.bsky.social
· 28d
Yuval Nir
@labnir.bsky.social
· 29d
Aperiodic EEG Activity Provides a Linear, Bidirectional, and Spatially Uniform Marker of Subjective and Objective Vigilance in Humans, Both Within and Across States
Vigilance is increasingly conceived as a continuum, ranging from full alertness to deep sleep. Despite its fundamental role in cognition, behaviour, and health, reliable physiological markers of vigil...
www.biorxiv.org
Yuval Nir
@labnir.bsky.social
· 29d
Sleep-like slow waves during wakefulness uncover a malignant form of Parkinson’s disease
Slow waves during sleep are fundamental for neural homeostasis, metabolic regulation, and waste clearance, and are known to be altered in neurodegenerative diseases. Sleep-like slow waves (SLSW) have ...
www.medrxiv.org
Yuval Nir
@labnir.bsky.social
· Aug 30
Human hippocampal ripples align new experiences with a grid-like schema
Xiao et al. show that brief bursts of hippocampal activity (ripples) help the brain
link new experiences into an internal “mental map.” During rest, ripples engage a
medial frontal brain region that o...
www.cell.com
Yuval Nir
@labnir.bsky.social
· Aug 20
Enhancement of Sleep Slow Wave Activity using Transcranial Electrical Stimulation with Temporal Interference
Slow waves mediate restorative functions of non-rapid eye movement (NREM) sleep. To enhance slow wave activity (SWA, 0.5-4 Hz) non-invasively, we employed a novel neuromodulatory tool, Transcranial El...
www.medrxiv.org
Reposted by Yuval Nir
Omer Sharon
@omersharon.bsky.social
· Aug 11
Anticipatory eye gaze as a marker of memory - Communications Psychology
Anticipatory eye movements during repeated movie viewing reveal when and what is remembered. Gaze patterns correlate with explicit reports, offering a method to detect memory for events without verbal...
www.nature.com
Yuval Nir
@labnir.bsky.social
· Aug 11
Temporal drift of sleep-wake representations in hypothalamic neuronal ensembles
Correlative and causal evidence implicate distinct genetically-defined and evolutionary-conserved hypothalamic neurons in regulating wakefulness, non-rapid eye movement (NREM), and rapid eye movement ...
www.researchsquare.com
Yuval Nir
@labnir.bsky.social
· Aug 5
Closed-loop electrical stimulation prevents focal epilepsy progression and long-term memory impairment
Nature Neuroscience - Pathological neural communication drives the spread of the epileptic network and contributes to memory impairment in focal epilepsy. The authors show that closed-loop...
rdcu.be
Yuval Nir
@labnir.bsky.social
· Aug 4
Sleep-like Slow Waves During Wakefulness Mediate Attention and Vigilance Difficulties in Adult Attention-Deficit/Hyperactivity Disorder
Background Attention-Deficit/Hyperactivity Disorder (ADHD) is characterised by behavioural variability and heightened inattention associated with increased mind wandering (MW) and mind blanking (MB). ...
www.biorxiv.org
Yuval Nir
@labnir.bsky.social
· Aug 3
A role for the thalamus in danger evoked awakening during sleep - Nature Communications
The extent to which the sleeping brain can discern safety from danger is poorly understood. In mice, the authors show that centro-medial thalamic neurons detect threat-related sounds and selectively t...
www.nature.com
Yuval Nir
@labnir.bsky.social
· Jun 26
Closed-loop electrical stimulation prevents focal epilepsy progression and long-term memory impairment - Nature Neuroscience
Pathological neural communication drives the spread of the epileptic network and contributes to memory impairment in focal epilepsy. The authors show that closed-loop electrical stimulation in rodents...
www.nature.com
Yuval Nir
@labnir.bsky.social
· Jun 19
Sleep need–dependent plasticity of a thalamic circuit promotes homeostatic recovery sleep
Prolonged wakefulness leads to persistent, deep recovery sleep (RS). However, the neuronal circuits that mediate this process remain elusive. From a circuit screen in mice, we identified a group of th...
www.science.org
