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Reposted by The Lancet Child & Adolescent Health

The Lancet Neurology @thelancetneuro.bsky.social · 19d

Our October issue is out - featuring biomarkers for sudden unexpected death in epilepsy, developments in the diagnosis of multiple sclerosis, climate change & brain health and much more!

Check it out here: tinyurl.com/3z5u36e7

#Neurology #BrainHealth

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Reposted by The Lancet Child & Adolescent Health

The Lancet @thelancet.com · 19d

With global obesity prevalence surpassing that of underweight among children & adolescents, harmful food environments & weak policies threaten lifelong health.

What can we do to address this global health crisis?

Find out more in our latest Editorial: tinyurl.com/3cnvctkv

Girl with healthy meal on tray at school cafeteria. Copyright: Westend61/Getty Images.

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Reposted by The Lancet Child & Adolescent Health

The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 18d

Published in The Lancet @thelancet.com:

The future of type 1 #diabetes therapy www.thelancet.com/journals/lan...
#T1D
#OpenAccess

#MedSky #EndoSky

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Reposted by The Lancet Child & Adolescent Health

The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 18d

In The Lancet @thelancet.com:
Minimum effective low dose of antithymocyte globulin in people aged 5–25 years with recent-onset stage 3 type 1 #diabetes (MELD-ATG): a phase 2, multicentre, double-blind, randomised, placebo-controlled, adaptive dose-ranging trial www.thelancet.com/journals/lan... #T1D

Minimum effective low dose of antithymocyte globulin in people aged 5–25 years with recent-onset stage 3 type 1 diabetes (MELD-ATG): a phase 2, multicentre, double-blind, randomised, placebo-controlle...

In young people with recent-onset, clinical type 1 diabetes, 2·5 mg/kg and 0·5 mg/kg ATG reduced loss of β-cell function, showing the potential of an affordable, repurposed agent, ATG, in a low and sa...

www.thelancet.com

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Reposted by The Lancet Child & Adolescent Health

The Lancet @thelancet.com · 15d

Join Zoë Mullan and other Lancet Group editors to learn more about the SAGER guidelines for sex- and gender-based analyses, explore real research examples, and gain practical tips for responding to the guidelines.

📅 21 October, 2pm BST
👉 Register: hubs.li/Q03FQ_6l0

Join our Lancet Webinar on the importance of analysing, reporting, and interpreting data according to sex and gender. Copyright: Elsevier Ltd.

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Reposted by The Lancet Child & Adolescent Health

The Lancet Rheumatology @thelancetrheum.bsky.social · 15d

Our October issue is live!

Including research on #vaccination in #rheumatoidarthritis and
#hydroxychloroquine during #pregnancy, two Reviews on #VEXAS, plus much more! thelancet.com/journals/lan...
Cover by Sara Gironi Carnevale #Medsky #Rheumsky

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Reposted by The Lancet Child & Adolescent Health

The Lancet @thelancet.com · 13d

NCDs affect more than 2 billion children and adolescents each year.

In a new letter, authors call for a shift from generalised #NCD strategies to specific, child-centred commitments backed by:
➡️ Global frameworks
➡️ Measurable targets
➡️ Long-term investment

🔗 tinyurl.com/3ryn7w74

Quote from a correspondence published in The Lancet entitled 'Improving survival and reducing suffering for children with NCDs.' Quote reads: [The Fourth High-level Meeting of the UN General Assembly6 on the prevention and control of NCDs] is an opportunity to galvanise a global movement for children with chronic and catastrophic diseases, especially cancers and sickle cell disease, and ensure they are no longer left behind.

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Reposted by The Lancet Child & Adolescent Health

The Lancet Infectious Diseases @thelancetinfdis.bsky.social · 13d

Read our October issue!

Featuring a trial testing moxidectin for lymphatic filariasis, bedaquiline resistance and tuberculosis outcomes, and a recombinant influenza vaccine for children.

www.thelancet.com/issue/S1473-...

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The Lancet Child & Adolescent Health @lancetchildadol.bsky.social · 12d

Read the linked Comment by Maria Antonietta De Ioris & Franco Locatelli: Long-term sequelae in survivors of high-risk neuroblastoma: the price of success

www.thelancet.com/journals/lan...

Long-term sequelae in survivors of high-risk neuroblastoma: the price of success

Until 2000, neuroblastoma was one of the deadliest tumours of childhood, with probabilities of long-term survival not exceeding 30%. In the past two decades, children with high-risk neuroblastoma have...

www.thelancet.com

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The Lancet Child & Adolescent Health @lancetchildadol.bsky.social · 12d

New online: Late effects after high-risk #neuroblastoma (LEAHRN): a multicentre, cross-sectional cohort study from the Children's Oncology Group

bit.ly/48zRnpK

@danafarber.bsky.social @sickkidsto.bsky.social @childrensphila.bsky.social @stjuderesearch.bsky.social @cityofhope.bsky.social

Late effects after high-risk neuroblastoma (LEAHRN): a multicentre, cross-sectional cohort study from the Children's Oncology Group

Survivors of high-risk neuroblastoma treated with modern therapies demonstrated a substantial burden of late effects, providing crucial information for future care and clinical trial design.

www.thelancet.com

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The Lancet Child & Adolescent Health @lancetchildadol.bsky.social · 12d

Explore the new data on the global burden of #cancer in children, adolescents, & young adults

"Childhood cancers occurring in the 0–14 year age range comprised 1·4% of all cancer cases and 1·0% of all cancer deaths globally in 2023, but 3·2% of all cancer DALYs"

Childhood Cancer Awareness Month

The Lancet @thelancet.com · 13d

Cancer deaths expected to rise to over 18 million in 2050—an increase of nearly 75% from 2024, study forecasts.

Explore the data ▶️ tinyurl.com/5n7dfnws @ihmeuw.bsky.social #NCDs

Figure: Global age-specific cancer (A) incidence and (B) mortality in 2023 for all sexes combined. Results are presented by 5-year age group. Left panels present age-specific incidence and mortality rates. Right panels present age-specific new case and death proportions. Copyright: 2025 Elsevier Ltd. All rights are reserved.

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The Lancet Child & Adolescent Health @lancetchildadol.bsky.social · 12d

Our editorial, published in advance of our November issue, discusses challenges around quality of life in #childhoodcancer in the context of global child & adolescent health

#free to read

www.thelancet.com/journals/lan...

Childhood Cancer Awareness Month #PedSky #OncSky

Surviving and thriving after childhood cancer

Without treatment, childhood cancer is fatal. However, in regions and settings with access to safe and effective therapies and supportive care, it is eminently survivable. But survival comes at the co...

www.thelancet.com

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Reposted by The Lancet Child & Adolescent Health

The Lancet @thelancet.com · 21d

📢 Join our webinar on sex and gender reporting in research

📅 Tues, 21 October, 2pm BST
👉 Register: hubs.li/Q03FQ_6l0

Our editors will guide you through our requirements for sex- and gender-based analyses, and share practical tips and examples of well-analysed research

Join our webinar on the importance of analysing, reporting, and interpreting data according to sex and gender on Tues, Oct 21, 2025 at 2pm BST/9am EDT. The Lancet Webinars. Copyright: Elsevier Ltd.

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Reposted by The Lancet Child & Adolescent Health

The Lancet Infectious Diseases @thelancetinfdis.bsky.social · 21d

New Research:

Safety, tolerability, and protective efficacy of a radiation-attenuated, whole sporozoite malaria vaccine in children in Gabon: a randomised, double-blind, placebo-controlled, phase 2 trial

www.thelancet.com/journals/lan...

Safety, tolerability, and protective efficacy of a radiation-attenuated, whole sporozoite malaria vaccine in children in Gabon: a randomised, double-blind, placebo-controlled, phase 2 trial

PfSPZ Vaccine is well tolerated and safe, but it did not prevent P falciparum infection in children in Gabon. Whether presumptive treatment during immunisation or more potent PfSPZ vaccines can establ...

www.thelancet.com

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The Lancet Child & Adolescent Health @lancetchildadol.bsky.social · 22d

All clinical research and review in child & adolescent health across @thelancet.com group conveniently in one place 👇

www.thelancet.com/collections/...

#PedSky

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Reposted by The Lancet Child & Adolescent Health

The Lancet @thelancet.com · 22d

Parent-focused programs insufficient to prevent obesity in toddlers, finds meta-analysis; authors call for a re-think of childhood obesity prevention approaches.

Explore the research ▶️ tinyurl.com/4mxaaypx

Parent-focused behavioural interventions for the prevention of early childhood obesity (TOPCHILD): a systematic review and individual participant data meta-analysis

These findings indicate that examined parent-focused behavioural interventions are insufficient to prevent obesity at age 24 months (±6 months). This evidence highlights a need to re-think childhood o...

tinyurl.com

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The Lancet Child & Adolescent Health @lancetchildadol.bsky.social · 22d

Linked Commentary by Anna Maria Mandalakasa & colleagues: Childhood tuberculosis: robust funding and integrated solutions needed now

www.thelancet.com/journals/lan...

Childhood tuberculosis: robust funding and integrated solutions needed now

The USA has led the world in global health activities, providing US$278 billion to low-income and middle-income countries (LMICs) for health since 2000.1 Despite being only 0·3% of US Government spend...

www.thelancet.com

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The Lancet Child & Adolescent Health @lancetchildadol.bsky.social · 22d

New research from Nicolas Menzies & colleagues: Potential #paediatric #tuberculosis incidence and deaths resulting from interruption in programmes supported by international health aid, 2025–34: a mathematical modelling study

www.thelancet.com/journals/lan...

#PedSky #InternationalAid

Potential paediatric tuberculosis incidence and deaths resulting from interruption in programmes supported by international health aid, 2025–34: a mathematical modelling study

Without actions to restore discontinued services, cuts to health aid for tuberculosis and HIV programmes could result in millions of additional childhood tuberculosis cases and deaths in low-income an...

www.thelancet.com

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Reposted by The Lancet Child & Adolescent Health

The Lancet @thelancet.com · 26d

Shigellosis is the most common cause of invasive bloody diarrhoea in children younger than 5 years.

The prevention of infection with vaccination & sanitation strategies remains a crucial step in reducing worldwide morbidity & mortality.

Find out more ▶️ tinyurl.com/ard69t83

Figure showing the immunopathogenesis of Shigella infection in the colon. MAMPs=microbe-associated molecular patterns. DAMPs=damage-associated molecular patterns. NK=natural killer. Adapted from Schnupf and Sansonetti. Copyright: 2025 Elsevier Ltd. All rights are reserved.

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The Lancet Child & Adolescent Health @lancetchildadol.bsky.social · 26d

💡A new systematic review & meta-analysis in @thelancet.com concludes that "parent-focused behavioural interventions are insufficient to prevent obesity at age 24 months" suggesting that childhood obesity prevention approaches "need a re-think"

www.thelancet.com/journals/lan...

#MedSky #PedSky

Parent-focused behavioural interventions for the prevention of early childhood obesity (TOPCHILD): a systematic review and individual participant data meta-analysis

These findings indicate that examined parent-focused behavioural interventions are insufficient to prevent obesity at age 24 months (±6 months). This evidence highlights a need to re-think childhood o...

www.thelancet.com

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The Lancet Child & Adolescent Health @lancetchildadol.bsky.social · 26d

In advance of #WorldSepsisDay, a Reflection from Akash Deep & Melissa Mead

www.thelancet.com/journals/lan...

#SepsisAwarenessMonth

Beyond sepsis awareness: why some children still fall through the cracks

In 2014, when William Mead unexpectedly died of sepsis at just 12 months old, his mother, Melissa, transformed her grief into a relentless mission. She stepped into a world she had never imagined: end...

www.thelancet.com

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Reposted by The Lancet Child & Adolescent Health

The Lancet Oncology @thelancetoncol.bsky.social · 26d

🚨Our Sept issue is live - 25 years! thelancet.com/journals/lan...

📊Articles #renalcellcarcinoma, #prostatecancer, #meningioma, #thymiccarcinoma, & #colorectalcancer

Reviews: 📰 ESTRO and ASTRO plus endorsed guidelines on vol delineation & 📰 Common Sense Oncology and EORTC on reporting QoL data

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The Lancet Child & Adolescent Health @lancetchildadol.bsky.social · 28d

*NEW* Health Policy from Morris Gordon & colleagues: European and North American guidelines for treating irritable bowel syndrome and functional abdominal pain in childhood: a guide for health-care professionals

www.thelancet.com/journals/lan...

#MedSky #PedSky #GastroSky

European and North American guidelines for treating irritable bowel syndrome and functional abdominal pain in childhood: a guide for health-care professionals

Abdominal pain-related disorders of gut–brain interaction (AP-DGBI; including irritable bowel syndrome, functional abdominal pain—not otherwise specified, abdominal migraine, and functional dyspepsia)...

www.thelancet.com

Reposted by The Lancet Child & Adolescent Health

The Lancet Rheumatology @thelancetrheum.bsky.social · 29d

NEW RESEARCH—Serum biomarkers associated with baricitinib response in patients with juvenile idiopathic arthritis: a post-hoc analysis of the phase 3 JUVE-BASIS trial bit.ly/4nrPIqK #JIA #Medsky #Rheumsky

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Reposted by The Lancet Child & Adolescent Health

The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 29d

Our October Issue is now online, featuring prediabetes remission, obesity, type 1 diabetes, biased GLP-1 receptor agonists, type 2 diabetes, prolactin-secreting adenomas, malnutrition-related diabetes, food system, NCDs & much more www.thelancet.com/journals/lan...

#MedSky #EndoSky #OncSky

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