Langridge Lab
@langridgelab.bsky.social
640 followers 520 following 320 posts
Dr Gemma Langridge's bacterial niche adaptation lab group based @quadraminstitute.bsky.social
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eh-hayles.bsky.social
Lovely reminder from @langridgelab.bsky.social that today’s actually the first day of the final year of my PhD – only a slightly daunting prospect…
langridgelab.bsky.social
We are so pleased to share that our @stevenrudder.bsky.social passed his viva with flying colours today 🥳 👏🎉 Congratulations Dr Rudder!! Huge thank you to Adrain Egli & @alisonmather.bsky.social for examining #PhDone #AcademicChatter You have definitely left your mark on the group & will be missed🦆
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gemma-langridge.bsky.social
Delighted to share that @stevenrudder.bsky.social has passed his viva today!! Congratulations Dr Rudder, and a huge thank you to @alisonmather.bsky.social and Prof Adrian Egli for examining. Steven, this is so well deserved, we're all super proud of you #PhDone
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emmabeansworth.bsky.social
Delighted to celebrate with @stevenrudder.bsky.social, who has passed his viva today!! Cannot believe your time with the @langridgelab.bsky.social is already over but this is a long time coming & you deserve this so much! Go forth & do your 💩 but please stay in touch #PhDone #academicsky #PhD
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emmabeansworth.bsky.social
Well that's a wrap @biochemsoc.bsky.social #BioPhyChrom2025 thank you to the organisers & everyone here for contributing to a wonderful week. Looking forward to hopefully seeing you all again in Paris 🇫🇷

@danielabarilla.bsky.social
@damelab.bsky.social
@graingerlab.bsky.social
@vslioy.bsky.social
langridgelab.bsky.social
We couldn't really let this #postdocappreciationweek pass without pointing out that we've doubled our awesome postdoc quota this year 💪💪 Between Claire and @emmabeansworth.bsky.social this group runs like a well oiled machine and we can't thank you enough for it 🤩 #NPAW2025
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emmabeansworth.bsky.social
It's #postdocappreciationweek! this year for the 1st time I have a special shout out to the @langridgelab.bsky.social's other VIP (Very Important Postdoc). Claire Hill you are immense addition with your CHill nature. Thank you for taking a good share of the load in looking after the group🐧 #NPAW2025
langridgelab.bsky.social
We have been hearing great things about @biochemsoc.bsky.social #BioPhyChrom2025 & it looks like our Emma is having fun.. maybe too much?😉

Don't worry when she's back she will be writing a paper on this work showing that genomic rearrangement can impact #virulence & #AMR. Find Poster 9 to hear more
emmabeansworth.bsky.social
What a great 1st session @biochemsoc.bsky.social #BioPhyChrom2025. A great mix of talks & discussion points from all speakers

I am looking forward to sharing my work showing that genome structure variation can influence #virulence & #AMR. Come see me at poster 009
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emmabeansworth.bsky.social
What a great 1st session @biochemsoc.bsky.social #BioPhyChrom2025. A great mix of talks & discussion points from all speakers

I am looking forward to sharing my work showing that genome structure variation can influence #virulence & #AMR. Come see me at poster 009
langridgelab.bsky.social
We are looking forward to @vslioy.bsky.social visiting @quadraminstitute.bsky.social tomorrow and hearing about her work on aquired genes shape #Salmonella's chromatin.

We are also looking forward to Vicky taking @emmabeansworth.bsky.social to #BioPhyChrom2025... Peace & quite for a whole week!🤫
emmabeansworth.bsky.social
Ready for a week of thinking about DNA's 3rd dimension @biochemsoc.bsky.social's #BioPhyChrom2025. But 1st I'm excited to be hosting @i2bcparissaclay.bsky.social's @vslioy.bsky.social. I am sure her talk on Salmonella chromatin will bring exciting chats & opportunies to @quadraminstitute.bsky.social
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vslioy.bsky.social
UK mode ON 🇬🇧 #BioPhyChrom2025 ahead! First stop @quadraminstitute.bsky.social for some Salmonella chromatin chats with @emmabeansworth.bsky.social & @langridgelab.bsky.social
langridgelab.bsky.social
Eleanor's paper explores the #genomic #epidemiology of #COVID in Norfolk, UK during the #pandemic, showing the powers of #sequence surveillance

Also just happens to be featuring as 1 of the most read articles in @microbiologysociety.org's #MicrobialGenomics this month!

What a team! What a year!
Genomic epidemiology of SARS-CoV-2 in Norfolk, UK, March 2020–December 2022
In the UK, the COVID-19 Genomics UK Consortium (COG-UK) established a real-time national genomic surveillance system during the COVID-19 pandemic, producing centralized data for monitoring severe acut...
www.microbiologyresearch.org
langridgelab.bsky.social
Both papers are in @microbiologysociety.org's #MicrobialGenomics...

Steven's reveals within-host genome diversity of #Salmonella whilst highlighting the limits of single-colony #sequencing, showing diversity which impacts #AMR & transmission💊

He also submitted his thesis last week #PhDachievements
Genomic diversity of non-typhoidal Salmonella found in patients suffering from gastroenteritis in Norfolk, UK
Salmonella is a significant public health pathogen responsible for a wide spectrum of diseases, ranging from gastroenteritis to invasive non-typhoidal salmonellosis and enteric fever. Although advance...
www.microbiologyresearch.org
langridgelab.bsky.social
As we leave late summer behind & enter autumn & some normality, we have been able to get together to celebrate some awesome achievements by our @stevenrudder.bsky.social & @eh-hayles.bsky.social. In a Langridge lab tradition, both received their coasters of their 1st author papers in the group!🎉🥳🎊
langridgelab.bsky.social
Once you have read that gem why not treat yourself to another from Cailean's PhD with @gemma-langridge.bsky.social

This preprint uses genome-scale #metabolicmodelling to see how #trimethoprim effects 𝘌. 𝘤𝘰𝘭𝘪's metabolism & how these can be selectively counteracted with growth media supplementation
Genome-scale metabolic modelling of trimethoprim’s mode of action reveals free ATP salvaged to restore purine pool
Trimethoprim is a clinically important antibiotic for treating urinary tract infections yet its mechanism of killing remains elusive due to a cascade of effected metabolic reactions. Metabolites avail...
www.biorxiv.org
langridgelab.bsky.social
Big news! @quadraminstitute.bsky.social Microbe of the Month is Salmonella Typhi! A tiny troublemaker with a big history🦠 Check out Typhi's reel to learn about its genetic gymnastics and long-term love for Mary Mallon 💝 #MicrobeoftheMonth #SalmonellaSlay See @quadraminstitute on instagram for more!
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emmabeansworth.bsky.social
We heard a lot about how #COVID impacted the nation, but what happened locally?

Here @eh-hayles.bsky.social discusses her research exploring & understanding how #SARS-CoV-2 spread & evolved in #Norfolk during the #COVID-19 pandemic 🦠 & shows how we can use the past to be prepared for the future💪
How SARS-CoV-2 impacted Norfolk: What a three year study taught us - Quadram Institute
“In the five years since COVID-19 was declared a pandemic, we’ve learnt a lot – not just about the virus that causes COVID-19 (SARS-CoV-2) but also how to track the spread and evolution of microbes th...
quadram.ac.uk
langridgelab.bsky.social
Waiting for the rain to stop? ⛈️ Need a good read? 📃

Our @eh-hayles.bsky.social has written a blog discussing her research exploring & understanding how SARS-CoV-2 spread & evolved in #Norfolk during the #COVID-19 pandemic 🦠

She shows the powers of #sequence surveillance & #epidemiology💪
How SARS-CoV-2 impacted Norfolk: What a three year study taught us - Quadram Institute
“In the five years since COVID-19 was declared a pandemic, we’ve learnt a lot – not just about the virus that causes COVID-19 (SARS-CoV-2) but also how to track the spread and evolution of microbes th...
quadram.ac.uk
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quadraminstitute.bsky.social
🆕 Blog! Our PhD student @eh-hayles.bsky.social discusses her research exploring and understanding how SARS-CoV-2 spread and evolved in #Norfolk during the COVID-19 pandemic 🦠

➡️ buff.ly/YgTTNVG
Reposted by Langridge Lab
langridgelab.bsky.social
Prefer to hear about the latest, awesome science in podcast summary instead of reading the entire paper?

Our @eh-hayles.bsky.social's @microbiologysociety.org paper has already been turned into a podcast episode!

Listen here or read the paper here www.microbiologyresearch.org/content/jour...
Genomic epidemiology of SARS-CoV-2 in Norfolk, UK, March 2020–December 2022
ReSay · Episode
open.spotify.com
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emmabeansworth.bsky.social
During the #COVID19 pandemic @quadraminstitute.bsky.social, sequenced >87,000 #SARSCoV2 samples, with an emphasis on East Anglia, supporting local hospitals with data informed insights on the emerging pandemic with #COGUK. This paper explores the #genomic #epidemiology of SARS-CoV-2 in Norfolk, UK
Genome sequencing SARS-CoV-2 plays a critical role in informing national and international COVID-19 public health responses - Quadram Institute
Quadram Institute researchers contributed to genomic surveillance of COVID-19, supporting national and international response to the pandemic
quadram.ac.uk