Laura Orian
@laura-orian.bsky.social
🔥Designing probes for TrxR! 🔥Check our collaborative paper in Angewandte Chemie with Oliver Thorn-Seshold and Elias Arner
Excellent work Lukas and Andrea! doi.org/10.1002/anie...
Excellent work Lukas and Andrea! doi.org/10.1002/anie...
Bicyclic Selenenyl Sulfides with Tuned Bioreductive Step Rates Reveal Constraints for Probes Targeting Thioredoxin Reductase
Thiol reductants activate dichalcogenide probes by a cascade of partly reversible steps. Careful dichalcogenide engineering can tune the rates of these steps separately, to aim at probes that are kin....
doi.org
July 28, 2025 at 6:31 AM
🔥Designing probes for TrxR! 🔥Check our collaborative paper in Angewandte Chemie with Oliver Thorn-Seshold and Elias Arner
Excellent work Lukas and Andrea! doi.org/10.1002/anie...
Excellent work Lukas and Andrea! doi.org/10.1002/anie...
Today 🔥I Magi Chimici🔥 playing at Liceo artistico Modigliani! Mora than 300 students from the secondary school with their teachers enjoy lots of magic tricks … well chemical experiments! @discunipd @UniPadova PIANO LAUREE SCIENTIFICHE Chimica 2021-23
May 31, 2025 at 8:38 AM
Today 🔥I Magi Chimici🔥 playing at Liceo artistico Modigliani! Mora than 300 students from the secondary school with their teachers enjoy lots of magic tricks … well chemical experiments! @discunipd @UniPadova PIANO LAUREE SCIENTIFICHE Chimica 2021-23
☀️accurate benchmark on (oxidized) organodichalcogenides!! ☀️ Organodichalcogenide Structure and Stability: Hierarchical Ab Initio Benchmark and DFT Performance Study - Beutick - 2025 - Journal of Computational Chemistry - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/...
Organodichalcogenide Structure and Stability: Hierarchical Ab Initio Benchmark and DFT Performance Study
We performed a double-hierarchical ab initio benchmark study of CH3Ch1<span class='icomoon'></span>Ch2(O)nCH3 (Ch1, Ch2 = S, Se; n = 0, 1, 2). Assessment of 33 DFT functionals showed M06 and MN15 provide accurate geometries and...
onlinelibrary.wiley.com
May 27, 2025 at 6:06 AM
☀️accurate benchmark on (oxidized) organodichalcogenides!! ☀️ Organodichalcogenide Structure and Stability: Hierarchical Ab Initio Benchmark and DFT Performance Study - Beutick - 2025 - Journal of Computational Chemistry - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/...
Activation of H2O2: Tellurium better than Selenium?👀 Glutathione Peroxidase-Like Activity of Functionalized Tellurides: Insights into the Oxidation Mechanism Through Activation Strain Analysis | Inorganic Chemistry pubs.acs.org/doi/10.1021/...
Glutathione Peroxidase-Like Activity of Functionalized Tellurides: Insights into the Oxidation Mechanism Through Activation Strain Analysis
The recent synthesis of a series of diorganotellurides as glutathione peroxidase mimics has prompted our in silico investigation on their oxidation mechanism by H2O2 at the ZORA-M06/TZ2P-ae//ZORA-OLYP...
pubs.acs.org
May 10, 2025 at 7:58 AM
Activation of H2O2: Tellurium better than Selenium?👀 Glutathione Peroxidase-Like Activity of Functionalized Tellurides: Insights into the Oxidation Mechanism Through Activation Strain Analysis | Inorganic Chemistry pubs.acs.org/doi/10.1021/...
👀Interested in fundamental mechanistic details on halogens binding and activation by model anti hyperthyroidism drugs?in silico … 💻All in this in our recent paper!😊💪 doi.org/10.1002/chem...
Dihalogens Binding and Activation by Imidazoline‐2‐Chalcogenone Model Derivatives: Insight from a Computational Approach
Chalcogenone donors represent a fundamental chemical class of compounds in the treatment of hyperthyroidism; particularly, imidazoline-based systems are associated with the strongest affinity for I2....
doi.org
May 4, 2025 at 10:29 AM
👀Interested in fundamental mechanistic details on halogens binding and activation by model anti hyperthyroidism drugs?in silico … 💻All in this in our recent paper!😊💪 doi.org/10.1002/chem...
☀️New interesting piece of research about Pd based antitumor drugs! ☀️Strongly collaborative work!💪 doi.org/10.1039/D5RA...
Influence of the charge of 1,3,5-triaza-7-phosphaadamantane-based ligands on the anticancer activity of organopalladium complexes
In this study, we report the synthesis and characterization of novel organopalladium complexes featuring 1,3,5-triaza-7-phosphaadamantane (PTA)-based ligands, including several cationic derivatives pr...
doi.org
May 4, 2025 at 10:26 AM
☀️New interesting piece of research about Pd based antitumor drugs! ☀️Strongly collaborative work!💪 doi.org/10.1039/D5RA...
Let’s read a book! 📕More than 200 students of the secondary school read the book ☀️L’interpretazione chimica del vivente ☀️by Giovanni Villani and presented and commented the different chapters at Istituto Scalcerle in Padova! With Valentina Domenici and Giovanni Villani
April 16, 2025 at 6:03 AM
Let’s read a book! 📕More than 200 students of the secondary school read the book ☀️L’interpretazione chimica del vivente ☀️by Giovanni Villani and presented and commented the different chapters at Istituto Scalcerle in Padova! With Valentina Domenici and Giovanni Villani
With Saverio Santi @discunipd.bsky.social and Luigi Biasetto, Massimiliano Alajmo and Lorenzo Dante Ferro… it’s a pity that the perfumes 🌺 , the essences 🌺 and the flavors 🌺 we tasted yesterday with the teachers of the secondary school cannot be posted and shared 🤷🏻♀️
April 12, 2025 at 2:31 PM
With Saverio Santi @discunipd.bsky.social and Luigi Biasetto, Massimiliano Alajmo and Lorenzo Dante Ferro… it’s a pity that the perfumes 🌺 , the essences 🌺 and the flavors 🌺 we tasted yesterday with the teachers of the secondary school cannot be posted and shared 🤷🏻♀️
ESU 2025 prize! Piano nazionale lauree scientifiche chimica @UniPadova @CaFoscari 200 students and teachers from the secondary school and staff from the univ departments! Tired … but happy!
April 8, 2025 at 5:10 AM
ESU 2025 prize! Piano nazionale lauree scientifiche chimica @UniPadova @CaFoscari 200 students and teachers from the secondary school and staff from the univ departments! Tired … but happy!
Reposted by Laura Orian
Bicyclic selenenyl sulfides tune stepwise rates of thiol/selenol addition, resolution, and cyclisation, to reveal cellular constraints for bioreductive probes targeting mammalian thioredoxin reductase
Authors: Lukas Zeisel, Lucas Dessen-Weissenhorn, ...
DOI: 10.26434/chemrxiv-2025-6vbn2
Authors: Lukas Zeisel, Lucas Dessen-Weissenhorn, ...
DOI: 10.26434/chemrxiv-2025-6vbn2
February 25, 2025 at 1:24 PM
Bicyclic selenenyl sulfides tune stepwise rates of thiol/selenol addition, resolution, and cyclisation, to reveal cellular constraints for bioreductive probes targeting mammalian thioredoxin reductase
Authors: Lukas Zeisel, Lucas Dessen-Weissenhorn, ...
DOI: 10.26434/chemrxiv-2025-6vbn2
Authors: Lukas Zeisel, Lucas Dessen-Weissenhorn, ...
DOI: 10.26434/chemrxiv-2025-6vbn2
Sperimentando exhibition: great science for great school students 👍
This year the topic is … water!
This year the topic is … water!
March 30, 2025 at 6:50 PM
Sperimentando exhibition: great science for great school students 👍
This year the topic is … water!
This year the topic is … water!
200 students and chemistry teachers from the secondary schools, students, staff and professors from UNIPD and UNIVE chemistry departments … discovering the beauties of art and chemistry in Venice. 12 km, 49 bridges … su e zo per i ponti 45 ed! 💪
March 25, 2025 at 7:01 AM
200 students and chemistry teachers from the secondary schools, students, staff and professors from UNIPD and UNIVE chemistry departments … discovering the beauties of art and chemistry in Venice. 12 km, 49 bridges … su e zo per i ponti 45 ed! 💪
☀️ Chalcogen Role in the ROS Scavenging Mechanism of Model Phenyl Compounds☀️ Great work by Davide Zeppilli, Veronica Pedergnana and Matteo Filippi ☀️ doi.org/10.3390/mole...
doi.org
March 25, 2025 at 6:48 AM
☀️ Chalcogen Role in the ROS Scavenging Mechanism of Model Phenyl Compounds☀️ Great work by Davide Zeppilli, Veronica Pedergnana and Matteo Filippi ☀️ doi.org/10.3390/mole...