Lawrence Lynn
@lawrencelynn.bsky.social
Pulmonary and Critical Care Research Physician.
Pinned
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the "RCT mimic" - PubMed
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly produced non-reproducible results, at times leading to high-impact reversals of global protocols when …
pubmed.ncbi.nlm.nih.gov
If you are a young critical care scientist do not miss this critical care review. The landscape of critical care science is about to change. Be sure to stay ahead of the wave.
@sccmcriticalcare.bsky.social
@criticalcare.bsky.social
@criticalcarereviews.com
pubmed.ncbi.nlm.nih.gov/41402862/
@sccmcriticalcare.bsky.social
@criticalcare.bsky.social
@criticalcarereviews.com
pubmed.ncbi.nlm.nih.gov/41402862/
@basakcoruh.bsky.social
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:59 PM
@basakcoruh.bsky.social
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
@janhansel.bsky.social
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:59 PM
@janhansel.bsky.social
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
@biosepsis.bsky.social
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:58 PM
@biosepsis.bsky.social
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
@criticalcare.bsky.social
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:57 PM
@criticalcare.bsky.social
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
@dilipj1.bsky.social
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:56 PM
@dilipj1.bsky.social
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
@stephen-t-webb.bsky.social
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:56 PM
@stephen-t-webb.bsky.social
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
@ics-updates.bsky.social
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:54 PM
@ics-updates.bsky.social
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the patient safety need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
@critcarescience.bsky.social
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:51 PM
@critcarescience.bsky.social
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
@sccm-research.bsky.social
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:50 PM
@sccm-research.bsky.social
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
@sccm-pediatrics.bsky.social
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:49 PM
@sccm-pediatrics.bsky.social
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
@sccmmw.bsky.social
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:49 PM
@sccmmw.bsky.social
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
@sccm-research.bsky.social
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:48 PM
@sccm-research.bsky.social
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for critical care clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
@jclinepi.bsky.social
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:46 PM
@jclinepi.bsky.social
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
@jci.org
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:46 PM
@jci.org
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
@erc.europa.eu
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:45 PM
@erc.europa.eu
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
@cochrane.org
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:44 PM
@cochrane.org
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
@cantrain.bsky.social
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:43 PM
@cantrain.bsky.social
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
@primarycaretrials.bsky.social
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:43 PM
@primarycaretrials.bsky.social
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
@imperialctu.bsky.social
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:42 PM
@imperialctu.bsky.social
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for clinical trial reform by forwarding this review.
pssjournal.biomedcentral.com/articles/10....
@southamptonctu.bsky.social
Help raise awareness of the need for reform in clinical trials by forwarding this analysis of critical care clinical trial science.,
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for reform in clinical trials by forwarding this analysis of critical care clinical trial science.,
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:41 PM
@southamptonctu.bsky.social
Help raise awareness of the need for reform in clinical trials by forwarding this analysis of critical care clinical trial science.,
pssjournal.biomedcentral.com/articles/10....
Help raise awareness of the need for reform in clinical trials by forwarding this analysis of critical care clinical trial science.,
pssjournal.biomedcentral.com/articles/10....
@scharr-msg.bsky.social
Help us reform critical care science and clinical trials. Forward to raise awareness
pssjournal.biomedcentral.com/articles/10....
Help us reform critical care science and clinical trials. Forward to raise awareness
pssjournal.biomedcentral.com/articles/10....
pssjournal.biomedcentral.com
January 6, 2026 at 1:31 PM
@scharr-msg.bsky.social
Help us reform critical care science and clinical trials. Forward to raise awareness
pssjournal.biomedcentral.com/articles/10....
Help us reform critical care science and clinical trials. Forward to raise awareness
pssjournal.biomedcentral.com/articles/10....
Reposted by Lawrence Lynn
Quand beaucoup de d'etudes randomisees dans votre spécialité sont des échecs, il faut se poser des questions...
@lawrencelynn.bsky.social l'a fait
@lawrencelynn.bsky.social l'a fait
@damienbarraudmd.bsky.social @load-dependent.bsky.social
Most respectfully, & I genuinely mean that, show some intellectual spine!
Retire safely colonized, or act & spare the next generation of critical-care mentees from repeating your fate, decades spent safely agonizing above the epistemic deck
Most respectfully, & I genuinely mean that, show some intellectual spine!
Retire safely colonized, or act & spare the next generation of critical-care mentees from repeating your fate, decades spent safely agonizing above the epistemic deck
Bone showed us that you could take many different diseases, pass them through a shared disease agnostic triage threshold, and study them as one population. That made large trials easier but it also disconnected them from causation. The world was intellectually colonized by US critical care science
January 6, 2026 at 1:25 PM
Quand beaucoup de d'etudes randomisees dans votre spécialité sont des échecs, il faut se poser des questions...
@lawrencelynn.bsky.social l'a fait
@lawrencelynn.bsky.social l'a fait
@oxfordstatistics.bsky.social
Help us reform critical care science and clinical trials. Forward to raise awareness
pssjournal.biomedcentral.com/articles/10....
Help us reform critical care science and clinical trials. Forward to raise awareness
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:26 PM
@oxfordstatistics.bsky.social
Help us reform critical care science and clinical trials. Forward to raise awareness
pssjournal.biomedcentral.com/articles/10....
Help us reform critical care science and clinical trials. Forward to raise awareness
pssjournal.biomedcentral.com/articles/10....
@clevelandclinicmls.bsky.social
Help us reform critical care science and clinical trials. Forward to raise awareness
pssjournal.biomedcentral.com/articles/10....
Help us reform critical care science and clinical trials. Forward to raise awareness
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:25 PM
@clevelandclinicmls.bsky.social
Help us reform critical care science and clinical trials. Forward to raise awareness
pssjournal.biomedcentral.com/articles/10....
Help us reform critical care science and clinical trials. Forward to raise awareness
pssjournal.biomedcentral.com/articles/10....
@medsci.ox.ac.uk
Help us reform critical care science and clinical trials. Forward to raise awareness
pssjournal.biomedcentral.com/articles/10....
Help us reform critical care science and clinical trials. Forward to raise awareness
pssjournal.biomedcentral.com/articles/10....
Flawed design and selection bias in critical care randomized controlled trials (RCTs): the patient safety risk of the “RCT mimic” - Patient Safety in Surgery
Over three decades, randomized controlled trials (RCTs) for critical care syndromes such as acute respiratory distress syndrome (ARDS), sepsis, and community acquired pneumonia (CAP) have repeatedly p...
pssjournal.biomedcentral.com
January 6, 2026 at 1:24 PM
@medsci.ox.ac.uk
Help us reform critical care science and clinical trials. Forward to raise awareness
pssjournal.biomedcentral.com/articles/10....
Help us reform critical care science and clinical trials. Forward to raise awareness
pssjournal.biomedcentral.com/articles/10....