@leosong.bsky.social
Reposted
During my postdoc in @therubinlab.bsky.social, @leosong.bsky.social and I aimed to make CRISPR-associated transposons more efficient for editing bacteria.
Couldn’t have done it w/o a CAST of characters at IGI and beyond @innovativegenomics.bsky.social, @cresslab.bsky.social, @doudna-lab.bsky.social
Couldn’t have done it w/o a CAST of characters at IGI and beyond @innovativegenomics.bsky.social, @cresslab.bsky.social, @doudna-lab.bsky.social
Happy New Year from the Rubin Lab! 🎇
We're excited to start 2026 off with a fresh publication at @science.org Advances. Here, we identified a cast (😉) of host factors affecting VchCAST using genome-wide screens and validated their improvement or inhibition of CAST activity. (1/2)
We're excited to start 2026 off with a fresh publication at @science.org Advances. Here, we identified a cast (😉) of host factors affecting VchCAST using genome-wide screens and validated their improvement or inhibition of CAST activity. (1/2)
Identification of proteins influencing CRISPR-associated transposases for enhanced genome editing
Whole-genome screening reveals strategies to boost CRISPR-associated transposase genome editing efficiency.
www.science.org
January 5, 2026 at 9:39 PM
During my postdoc in @therubinlab.bsky.social, @leosong.bsky.social and I aimed to make CRISPR-associated transposons more efficient for editing bacteria.
Couldn’t have done it w/o a CAST of characters at IGI and beyond @innovativegenomics.bsky.social, @cresslab.bsky.social, @doudna-lab.bsky.social
Couldn’t have done it w/o a CAST of characters at IGI and beyond @innovativegenomics.bsky.social, @cresslab.bsky.social, @doudna-lab.bsky.social
Reposted
Our identification of homologous recombination effectors RecD and RecA guided coupling λ-Red recombineering with CAST, boosting editing efficiency in model (E. coli) and non-model (P. putida, K. michiganesis) Gammaprotebacteria, expanding CAST’s utility as a precise bacterial genome editor. (2/2)
January 5, 2026 at 6:45 PM
Our identification of homologous recombination effectors RecD and RecA guided coupling λ-Red recombineering with CAST, boosting editing efficiency in model (E. coli) and non-model (P. putida, K. michiganesis) Gammaprotebacteria, expanding CAST’s utility as a precise bacterial genome editor. (2/2)
Reposted
New in Science Magazine Science Advances from the Doudna Lab, Rubin Lab and Cress Lab —Identification of proteins influencing #CRISPR-associated #transposases for enhanced #GenomeEditing. Read here: https://ow.ly/U0s450XS82n
January 5, 2026 at 7:23 PM
New in Science Magazine Science Advances from the Doudna Lab, Rubin Lab and Cress Lab —Identification of proteins influencing #CRISPR-associated #transposases for enhanced #GenomeEditing. Read here: https://ow.ly/U0s450XS82n
Reposted
Happy New Year from the Rubin Lab! 🎇
We're excited to start 2026 off with a fresh publication at @science.org Advances. Here, we identified a cast (😉) of host factors affecting VchCAST using genome-wide screens and validated their improvement or inhibition of CAST activity. (1/2)
We're excited to start 2026 off with a fresh publication at @science.org Advances. Here, we identified a cast (😉) of host factors affecting VchCAST using genome-wide screens and validated their improvement or inhibition of CAST activity. (1/2)
Identification of proteins influencing CRISPR-associated transposases for enhanced genome editing
Whole-genome screening reveals strategies to boost CRISPR-associated transposase genome editing efficiency.
www.science.org
January 5, 2026 at 6:45 PM
Happy New Year from the Rubin Lab! 🎇
We're excited to start 2026 off with a fresh publication at @science.org Advances. Here, we identified a cast (😉) of host factors affecting VchCAST using genome-wide screens and validated their improvement or inhibition of CAST activity. (1/2)
We're excited to start 2026 off with a fresh publication at @science.org Advances. Here, we identified a cast (😉) of host factors affecting VchCAST using genome-wide screens and validated their improvement or inhibition of CAST activity. (1/2)
Reposted
Grad school panel event for the @innovativegenomics.bsky.social undergrad and tech journal club!
December 7, 2024 at 12:48 AM
Grad school panel event for the @innovativegenomics.bsky.social undergrad and tech journal club!