Lew Lab @ WashU
@lewlab.com
630 followers
470 following
19 posts
Playing with #singlemolecules, bending light, and algorithms to see really small things. Led by Matthew Lew, Associate Professor @WashUESE @WashUengineers @WashU #superresolution #microscopy #SMLM #computationalimaging
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Lew Lab @ WashU
@lewlab.com
· 20d
Single-molecule orientation and localization microscopy - Nature Photonics
The Review discusses recent advances in single-molecule orientation and localization microscopy (SMOLM) along with remaining challenges and promises for future developments of the field.
doi.org
Lew Lab @ WashU
@lewlab.com
· Apr 11
Rohit V. Pappu
@rohitpappu68.bsky.social
· Apr 11
Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates - Nature Communications
Experiments and computations show that the organization and dynamics of molecules within and at interfaces of biomolecular condensates are governed by differential interaction strengths leading to the...
www.nature.com
Lew Lab @ WashU
@lewlab.com
· Mar 21
Resolving the Orientations of and Angular Separation Between a Pair of Dipole Emitters
We prove that it is impossible to distinguish two spatially coinciding fluorescent molecules from a single rotating molecule using polarization-sensitive imaging, even if one modulates the polarizatio...
doi.org
Reposted by Lew Lab @ WashU
Reposted by Lew Lab @ WashU
Leah Shaffer
@leahshaffer.bsky.social
· Mar 14
Single-fluorogen imaging reveals distinct environmental and structural features of biomolecular condensates - Nature Physics
Experiments confirm the prediction that fluid-like biomolecular condensates are defined by spatially inhomogeneous organization of the underlying molecules.
www.nature.com
Lew Lab @ WashU
@lewlab.com
· Mar 14
Lew Lab @ WashU
@lewlab.com
· Mar 14
Reposted by Lew Lab @ WashU
Lew Lab @ WashU
@lewlab.com
· Jan 29
Fake papers are contaminating the world’s scientific literature, fueling a corrupt industry and slowing legitimate lifesaving medical research
‘Paper mills’ are contaminating the world’s scholarly output with fake papers that hinder research. Lifesaving biomedical fields are especially hard hit.
theconversation.com
Lew Lab @ WashU
@lewlab.com
· Dec 27
Lew Lab @ WashU
@lewlab.com
· Dec 26
Six-dimensional single-molecule imaging with isotropic resolution using a multi-view reflector microscope - Nature Photonics
A multi-view reflector microscope based on polarization modulation and pupil splitting enables single-molecule orientation-localization microscopy with precisions of 10.9 nm and 2.0°.
doi.org
Lew Lab @ WashU
@lewlab.com
· Dec 26
POLCAM: instant molecular orientation microscopy for the life sciences - Nature Methods
Combining localization and polarization microscopy can yield detailed insights into subcellular structures. POLCAM uses a polarization camera and wide-field microscopy for rapid measurement of super-r...
doi.org
