Background Pancreatic cancer (PANC) is often diagnosed at late stages due to the absence of specific early symptoms, resulting in one of the highest cancer mortality rates. While imaging modalities su...

Diabetes mellitus (DM) represents a significant global public health challenge, as economic development and changes in modern dietary habits have contributed to a rising prevalence of DM patients. Pancreatic cancer (PC), a highly aggressive malignancy, exhibits a 5-year survival rate of approximately 10%. The intricate and perilous relationship between DM and the onset and progression of PC is increasingly being elucidated, revealing a complex underlying network that encompasses multiple dimensions, including molecular signaling, metabolism, endocrinology, immunity, microbiota, and tumor microenvironment formation. Consequently, this review aims to delineate the overarching framework of the extensive relational network between DM and PC, focusing on the aforementioned aspects. Specifically, this review highlights the promoting effects of DM on the carcinogenic process of PC, emphasizing the complexity of the DM-PC interaction and identifying potential therapeutic targets for intervention. Graphic abstract

Femtosecond laser acts on collagen for selective ablation leaving healthy tissue intact.

450Background: Pancreatic cancer (PC) remains one of the deadliest malignancies, due to late-stage presentation and limited risk-reduction strategies. Certain high-penetrance germline variants increas...

This study attempts to determine the long-term oncological outcome of minimally invasive left pancreatectomy vs open left pancreatectomy in patients with upfront resectable left-sided pancreatic cance...

374Background: Pancreatic cancer is an aggressive disease which requires comprehensive care. Complex treatment paradigms require coordination of care amongst medical oncologists, radiation oncologists...

Innovative dual treatment shows promise in tackling deadly cancer

Study Demonstrated a Sensitivity of 100% and Specificity of 95%Mainz Biomed N.V. (NASDAQ:MYNZ) (“Mainz Biomed” or the “Company”), a molecular genetics diagnostic company specializing in the early dete...

Pancreatic neuroendocrine neoplasms (PNENs) are a rare form of cancer that affects hormone-producing cells in the pancreas. Although uncommon, their incidence has been rising steadily over the past fe...

In the relentless search for reliable prognostic markers in pancreatic ductal adenocarcinoma (PDAC), a new light has been shed on the role of fibroblast growth factor receptors (FGFRs). Recently

Cell Death & Disease - IRE1α translational suppression potentiates STING-dependent chemoresistance in pancreatic cancer

UT Southwestern Medical Center researchers have identified two distinct populations of cells known as antigen-presenting cancer-associated fibroblasts (apCAFs) that appear to support the survival and ...

My cancer journey began with a surgical oncologist who extracted my one-inch pancreatic tumor, taking with it the top third of my pancreas.

Martin F. Dietrich, MD, PhD, discusses the potential role of atebimetinib plus chemotherapy in frontline pancreatic cancer.

A new laser-based technique targets pancreatic ductal adenocarcinoma (PDAC) while leaving healthy tissue intact. 

Every cell in the human body operates on an intricate internal schedule, governed by circadian rhythms that synchronize our biological processes with

UCLA and the Hirshberg Foundation will host the UCLA Scientific Symposium on Pancreatic Cancer on Oct. 10, 2025, at UCLA Faculty Club

Learn about the immunotherapy success rate for pancreatic cancer, current outcomes, rare MSI-H responses, and future directions in treatment.

Cancer patients say the new centre will be

At the recent American Association for Cancer Research (AACR) Special Conference on Advances in Pancreatic Cancer Research, researchers from Cellectar Biosciences Inc. presented preclinical data on [2...

KRAS activating mutations occur in 90%-95% of pancreatic adenocarcinoma (PC) and contribute to tumor progression and resistance to therapy, including radiotherapy. A screen in isogenic cells revealed ...