Li-Bo ZHANG
@li-bo-zhang.bsky.social
Weeb scientist studying pain.
TIL
Introducing ParTIpy, a python package for Pareto Task Inference that scales to large-scale datasets, including single-cell and spatial transcriptomics.
🔗 Manuscript: www.biorxiv.org/content/10.1...
💻 Code: partipy.readthedocs.io
🔗 Manuscript: www.biorxiv.org/content/10.1...
💻 Code: partipy.readthedocs.io
December 28, 2025 at 2:20 AM
TIL
Today is the day "mind-blowing" makes sense.
No contest. Just read the first two sentences of the abstract. www.nature.com/articles/s41...
All right it’s time for the annual “please tell us about one (or a few if you are ambitious) paper from 2025 that really impressed you and why we should all read it“! Go! If you tell us how it changed your view of the world and what makes it so powerful and consequential It would be excellent.
December 21, 2025 at 11:45 PM
Today is the day "mind-blowing" makes sense.
How I lost and found my scientific creativity | Science | AAAS www.science.org/content/arti...
How I lost and found my scientific creativity
“I now encourage my graduate students and postdocs to disconnect and take time out to think, to play, to have fun with their research,” this professor writes
www.science.org
December 20, 2025 at 3:17 AM
How I lost and found my scientific creativity | Science | AAAS www.science.org/content/arti...
Reposted by Li-Bo ZHANG
E.B. White’s Beautiful Letter to a Man Who Had Lost Faith in Humanity
"As long as there is one upright man, as long as there is one compassionate woman, the contagion may spread and the scene is not desolate." x.com/themarginali... #humanity #faith
"As long as there is one upright man, as long as there is one compassionate woman, the contagion may spread and the scene is not desolate." x.com/themarginali... #humanity #faith
Maria Popova on X: ""As long as there is one upright man, as long as there is one compassionate woman, the contagion may spread and the scene is not desolate." E.B. White's beautiful letter to a man who had lost faith in humanity https://t.co/s4D5FQu9af" / X
"As long as there is one upright man, as long as there is one compassionate woman, the contagion may spread and the scene is not desolate." E.B. White's beautiful letter to a man who had lost faith in humanity https://t.co/s4D5FQu9af
x.com
December 8, 2025 at 6:26 PM
E.B. White’s Beautiful Letter to a Man Who Had Lost Faith in Humanity
"As long as there is one upright man, as long as there is one compassionate woman, the contagion may spread and the scene is not desolate." x.com/themarginali... #humanity #faith
"As long as there is one upright man, as long as there is one compassionate woman, the contagion may spread and the scene is not desolate." x.com/themarginali... #humanity #faith
"If you want to do biological research, you have to be prepared to fail."
November 27, 2025 at 4:01 AM
"If you want to do biological research, you have to be prepared to fail."
Reposted by Li-Bo ZHANG
🎓Recruiting Ph.D. students for Fall 2026!🎓
The Feilong Lab @sc.edu studies commonalities & differences across brains, and how they relate to cognition, language, & disorders.
We develop brain templates, improve hyperalignment, and compare human brains with monkey brains & DNNs.
feilonglab.github.io
The Feilong Lab @sc.edu studies commonalities & differences across brains, and how they relate to cognition, language, & disorders.
We develop brain templates, improve hyperalignment, and compare human brains with monkey brains & DNNs.
feilonglab.github.io
Feilong Lab @ UofSC — Feilong Lab
feilonglab.github.io
November 7, 2025 at 5:55 PM
🎓Recruiting Ph.D. students for Fall 2026!🎓
The Feilong Lab @sc.edu studies commonalities & differences across brains, and how they relate to cognition, language, & disorders.
We develop brain templates, improve hyperalignment, and compare human brains with monkey brains & DNNs.
feilonglab.github.io
The Feilong Lab @sc.edu studies commonalities & differences across brains, and how they relate to cognition, language, & disorders.
We develop brain templates, improve hyperalignment, and compare human brains with monkey brains & DNNs.
feilonglab.github.io
Reposted by Li-Bo ZHANG
Variability in #NeuralActivity is associated with cognition, but how does it relate to pain? @li-bo-zhang.bsky.social &co show that neural variability correlates with how individuals perceive #pain intensity in different contexts @plosbiology.org 🧪 plos.io/48QPR2S
![Neural variability does not encode interindividual sensory sensitivity but reflects intraindividual sensory perception. (A) Point-by-point partial correlations between trial-averaged SD ([High + Low]/2) and sensitivity measured by mean ratings ([High + Low]/2) to sensory stimuli of four modalities in Dataset 1 (N = 141). No significant correlations were found in any modality. Note that no gray bars are shown because none of the partial correlation coefficients survived FDR correction (all P values > 0.05). The color bars underneath display the corresponding Bayes factor values for the correlations. Note that part-corr is short for partial correlation. The light-colored “bursty” curves represent the subject-averaged residuals of mean SD after regressing out mean amplitude. (B) Point-by-point intraindividual correlations between neural variability and ratings to sensory stimuli for each trial in Dataset 1 (N = 141). The gray bars represent t-statistics at time points where significant differences were observed after FDR correction. (C) Point-by-point partial correlations between trial-averaged SD and mean ratings to sensory stimuli of four modalities in Datasets 2&3 (N = 225). (D) Point-by-point intraindividual correlations between neural variability and ratings to sensory stimuli for each trial in Datasets 2&3 (N = 225). These results illustrate that neural variability encodes sensory perception at the intraindividual level, but does not encode sensory sensitivity at the interindividual level.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:5522ztebtekoor5efelihqhb/bafkreibkwvpnw2iome7ah4acvcmfp3bfihj6y4ga6drnzrrpz5sumwfjzu@jpeg)
October 28, 2025 at 5:25 PM
Variability in #NeuralActivity is associated with cognition, but how does it relate to pain? @li-bo-zhang.bsky.social &co show that neural variability correlates with how individuals perceive #pain intensity in different contexts @plosbiology.org 🧪 plos.io/48QPR2S
Reposted by Li-Bo ZHANG
People are thinking about what is not happening almost as often as they are thinking about what is.
Doing so typically makes them unhappy.
www.science.org/doi/10.1126/...
Doing so typically makes them unhappy.
www.science.org/doi/10.1126/...
October 13, 2025 at 2:33 AM
People are thinking about what is not happening almost as often as they are thinking about what is.
Doing so typically makes them unhappy.
www.science.org/doi/10.1126/...
Doing so typically makes them unhappy.
www.science.org/doi/10.1126/...
Reposted by Li-Bo ZHANG
Randomized controlled trials are a key tool to study cause and effect. Why do they matter and how do they work?
September 24, 2025 at 2:15 PM
Randomized controlled trials are a key tool to study cause and effect. Why do they matter and how do they work?