Lia Obinu
liaobinu.bsky.social
Lia Obinu
@liaobinu.bsky.social
🌱🍄
🌱 🧬 New preprint out!

We built and annotated the first reference-free #pangenome of #Arabidopsis thaliana using PGGB (Pan-Genome Graph Builder), spanning 93 assemblies!

Check it out here 👉 www.biorxiv.org/content/10.1...

#Genomics #Bioinformatics
The reference-free pangenome of Arabidopsis thaliana
For several decades, scientists relied on unique reference genomes as the basis for various genomic studies. This methodology presents multiple drawbacks, particularly for variation studies, often yie...
www.biorxiv.org
June 30, 2025 at 4:00 PM
So proud to see Colora published in #Bioinformatics! 🐍✨
Colora automatically generates chromosome-scale de novo #genome assemblies — organelles included!
It’s open and ready to support your #biodiversity research! 🧬🌱🍄‍🟫🐝
Huge thanks to the amazing team I had the pleasure of working with! ☀️
Colora: a Snakemake workflow for complete chromosome-scale de novo genome assembly
AbstractMotivation. De novo assembly creates reference genomes that underpin many modern biodiversity and conservation studies. Large numbers of new genome
academic.oup.com
May 11, 2025 at 9:31 AM