Lightnews — Scholar-powered news

Ludwig Cancer Research

@ludwigcancer.bsky.social

2.9K followers 42 following 130 posts

We fund cutting-edge scientific research across multiple Branches and Centers to better understand cancer and eliminate the suffering caused by the disease.

Posts Media Videos Starter Packs

Pinned

Ludwig Cancer Research @ludwigcancer.bsky.social · May 29

The May 2025 edition of the Ludwig Link is here! Catch up on the latest from Ludwig researchers, including awards, new leadership and a gallery of beautiful (and fascinating) micrographs. Check it out online here bit.ly/3Fo6LJR or download the PDF bit.ly/3Sq6Uze

#CanSky #OncoSky

1 4

Reposted by Ludwig Cancer Research

Sarah Cherkaoui @cherkaos.bsky.social · 9d

🚨 Excited to share our new paper is out in Nature!
🔗 Reprogramming neuroblastoma by diet-enhanced polyamine depletion

Nature @nature.com · 9d

Nature research paper: Reprogramming neuroblastoma by diet-enhanced polyamine depletion

go.nature.com/4nLY0to

Reprogramming neuroblastoma by diet-enhanced polyamine depletion - Nature

Enhanced polyamine depletion in neuroblastoma models decreases translation of mRNA codons with adenosine in the third position, reprogramming the tumour proteome away from cell cycle progression and towards differentiation.

go.nature.com

1 4 8

Reposted by Ludwig Cancer Research

Nuffield Department of Medicine @ndm.ox.ac.uk · 23d

Today marks the start of #PostdocAppreciationWeek, so we're kicking it off by sharing our first of three videos celebrating postdocs here at NDM 📽️🥼

Watch @whitefishlab.bsky.social and two postdocs in his research group at @ludwigcancer.bsky.social Oxford in the video below 👀👇

#NPAW2025

2 4

Reposted by Ludwig Cancer Research

Beth Psaila @bethpsaila.bsky.social · 29d

‼️See below terrific opportunity for a postdoc post with a leading group in Oxford, super exciting science! 🔥🔥👇

Marketa Tomkova @marketatomkova.bsky.social · Sep 5

Please share: we’re recruiting a postdoctoral fellow – applications open until September 15!

To lead genomics data analysis of an exciting translational project in sAML cancer, supportive environment, and access to unique in-house technologies.

my.corehr.com/pls/uoxrecru...

Job Details

my.corehr.com

1 1 1

Ludwig Cancer Research @ludwigcancer.bsky.social · 14d

Congrats to Ludwig Institute Scientific Director Chi Van Dang, Ludwig Oxford Director Xin Lu, Ludwig Lausanne’s Mikael Pittet and Ludwig Stanford’s @michellemonje.bsky.social, whose teams have been picked as one of a dozen finalists for the prestigious @cancergrand.bsky.social award.
bit.ly/4mAhFvE

Ludwig Cancer Research @ludwigcancer.bsky.social · 15d

A team led by Ludwig Lausanne’s @johannajoyce.bsky.social & former postdoc @alvarezprado.bsky.social reports a potential drug target whose loss in certain GBM cells triggers antiviral alarms to stall cell proliferation & makes GBM tumors in mice more amenable to anti-cancer immunity.
bit.ly/4nhZ7Bj

5 10

Reposted by Ludwig Cancer Research

Richard White @whitefishlab.bsky.social · Aug 28

Cancer cells are notoriously plastic, but what triggers the changes in cell state? In our new Nature (@nature.com)‬ paper, Miranda Hunter (@mrndhntr.bsky.social‬) found that mechanical pressure is a key to this switch. Check it out here: go.nature.com/47iwDm2

7 21 59

Reposted by Ludwig Cancer Research

Nuffield Department of Medicine @ndm.ox.ac.uk · Aug 19

Platelets are known for blood clotting, but that's not all. Researchers at @ludwigcancer.bsky.social Oxford have discovered another function - suppressing systemic inflammation. This information has the potential to improve cancer detection going forward 🩸

Find out more 👉 buff.ly/tzbL1yh

5 2

Reposted by Ludwig Cancer Research

Johanna Joyce @johannajoyce.bsky.social · Sep 3

How can we reawaken the body’s own anti-viral defenses to fight brain cancer?

Delighted to share our new study where we now answer this question, led by the brilliant @alvarezprado.bsky.social who is now an independent PI at LIH Luxembourg 👏👏

#BrainTIME 🧠🦠🧪
🧵

www.sciencedirect.com/science/arti...

3 20 64

Ludwig Cancer Research @ludwigcancer.bsky.social · Sep 3

Researchers led Ludwig Princeton’s Yujiao Han and Yibin Kang have discovered how metastatic breast cancer cells employ mimicry and manipulation to thrive in the low-oxygen microenvironment of bone marrow—and how this trickery likely causes anemia in patients. bit.ly/4ncN2wM

#CanSky #OncoSky

Ludwig Cancer Research @ludwigcancer.bsky.social · Aug 19

Researchers led by Ludwig @ox.ac.uk’s @bethpsaila.bsky.social & @l-cmurphy.bsky.social have discovered that platelets help suppress systemic inflammation. The way they do so can be harnessed to improve the minimally invasive detection of cancer & the sensitivity of prenatal screening. bit.ly/4mOWVk4

Ludwig Cancer Research @ludwigcancer.bsky.social · Aug 8

Congratulations to Ludwig @unil.bsky.social's George Coukos on his election to the 2025 class of Fellows of the Academy of Immuno-Oncology!

#CanSky #OncoSky

Ludwig Cancer Research @ludwigcancer.bsky.social · Aug 7

Study co-led by Ludwig @weillcornell.bsky.social’s Tao Shi & Taha Merghoub with researchers in China shows how neutrophils are reprogrammed by bone metastases to suppress anti-tumor immune responses. Blocking that process restores the tumors’ sensitivity to immunotherapy. bit.ly/457Uwez

#CanSky

Ludwig Cancer Research @ludwigcancer.bsky.social · Jul 31

Researchers led by Ludwig @unil.bsky.social’s Denarda Dangaj Laniti & Eleonora Ghisoni have identified four immunologic subtypes of recurrent ovarian cancers and detailed how the gene expression and immune landscape of each evolve upon relapse to drive therapeutic resistance. bit.ly/3INfir8

#CanSky

Ludwig Cancer Research @ludwigcancer.bsky.social · Jul 30

Researchers led by Ludwig Princeton’s @lydialynch.bsky.social have discovered that in obese people, who are at high risk for many cancers, a diet rich in animal fats—but not plant-derived fats—suppresses antitumor immunity and promotes cancer progression. bit.ly/4fcfWu9

#CanSky #OncoSky

Ludwig Cancer Research @ludwigcancer.bsky.social · Jul 18

A team co-led by Ludwig ‪Weill Cornell’s Tao Shi and Taha Merghoub & colleagues in China has identified precursors of neutrophils that suppress anti-tumor immunity & drive tumor growth. They also propose a strategy to alter the developmental path of the cells for therapy. bit.ly/40Zz6xx

#CanSky

Ludwig Cancer Research @ludwigcancer.bsky.social · Jul 17

Researchers led by Ludwig @unil.bsky.social’s Ping-Chih Ho, Xiaoyun Li and Sofie Hedlund Møller report that cancer cells secrete fats that prompt fibroblasts to flip macrophages into a pro-cancer state. Disrupting this process impairs tumor growth in mouse models of melanoma. Details: bit.ly/3U5WYfj

Ludwig Cancer Research @ludwigcancer.bsky.social · Jul 10

Congrats to Ludwig Princeton’s Vanha Nhat Pham, who has been named the first Ludwig Cancer Research-Jane Coffin Childs Fellow @jcchildsfund.bsky.social. Pham plans to explore the roles molecular components of cell membranes known as phospholipids play in cellular physiology. bit.ly/463HJdQ

#CanSky

1 4

Ludwig Cancer Research @ludwigcancer.bsky.social · Jul 8

Ludwig @mit.edu’s Amy Wisdom sat down with us at the Center’s 2025 retreat to discusses her research on coaxing the immune system to target a deadly brain cancer and how collaboration has been essential to her studies. Check it out here: youtu.be/EyW9Fz4gG9c

#CanSky #OncoSky

Amy Wisdom

YouTube video by Ludwig Cancer Research

youtu.be

1 4

Ludwig Cancer Research @ludwigcancer.bsky.social · Jul 7

We congratulate Ludwig @ox.ac.uk’s Helen Byrne on her receipt of the Naylor Prize and Lectureship in Applied Mathematics from the London Mathematical Society for her incisive modeling of the heterogeneity, topological features and immune landscapes of tumors. bit.ly/4eysUlG

#CanSky #OncoSky

1 12

Ludwig Cancer Research @ludwigcancer.bsky.social · Jul 2

At the Ludwig @mit.edu 2025 retreat, @fsrmit.bsky.social took us through his lab’s scientific focus and his journey in cancer research, including his years in the Ludwig MIT community as, initially, a trainee and now a principal investigator. youtu.be/BvMZ8ETu6sM

#CanSky #OncoSky

Francisco Sánchez Rivera

YouTube video by Ludwig Cancer Research

youtu.be

Ludwig Cancer Research @ludwigcancer.bsky.social · Jun 30

A team led by Ludwig Lausanne’s Camilla Jandus identified a subset of CD4+ T cells that not only support the killing of cancer cells expressing a common cancer antigen but kill those cells themselves. They also harness these cells to devise a potential cancer immunotherapy. bit.ly/3TUtksY

#CanSky

Ludwig Cancer Research @ludwigcancer.bsky.social · Jun 30

We hosted the first in-person meeting of the multi-institutional Ludwig immunometabolism initiative in New York for a day of exciting discussions on their recent discoveries and ongoing studies exploring the interface of diet, cancer metabolism and anti-tumor immunity. bit.ly/4nGFkMG

#CanSky

Ludwig Cancer Research @ludwigcancer.bsky.social · Jun 27

Ludwig @mit.edu Co-director Tyler Jacks spoke with us at the Center’s 2025 retreat about his career and how interdisciplinary collaboration fuels cancer research at Ludwig MIT. Check it out here: youtu.be/dHJgSbvCc5Y

#CanSky #OncoSky

Tyler Jacks, Ludwig MIT

YouTube video by Ludwig Cancer Research

youtu.be

1 3

Ludwig Cancer Research @ludwigcancer.bsky.social · Jun 26

Check out the latest issue of eLudwigNews conta.cc/3TCMjbp and sign up for our newsletter to stay up to date on all Ludwig news bit.ly/LCRnews

#CanSky #OncoSky

Ludwig Cancer Research @ludwigcancer.bsky.social · Jun 12

Congratulations on 20 years @johannajoyce.bsky.social!

Johanna Joyce @johannajoyce.bsky.social · Jun 11

Celebrating 2️⃣0️⃣ years of the Joyce Lab 🎉

We had an amazing reunion, bringing together past & present lab members from Lausanne & NYC 🏔️🗽

Huge thanks to everyone who came from around the world, shared science & happy memories and together made this milestone really special 😍

#JoyceLab20 #ProudMentor