lwaleryszak.bsky.social
Léa Monge-Waleryszak
@lwaleryszak.bsky.social
34 followers 35 following 3 posts
PhD in Plant-Microbe Molecular Interactions
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lwaleryszak.bsky.social
Léa Monge-Waleryszak @lwaleryszak.bsky.social · May 26
Love uncovering effector virulence strategies! 😀
Our work on PopP2 targeting core components of the PEAT chromatin-remodeling complexes is now out @theplantjournal.bsky.social.
doi.org/10.1111/tpj....
Three ARID proteins involved in chromatin remodeling PEAT complexes are targeted by the Ralstonia solanacearum effector PopP2 and contribute to bacterial wilt disease
The Ralstonia solanacearum effector PopP2 is a YopJ family acetyltransferase. PopP2 is known to dampen basal immune responses by acetylating defensive WRKY transcription factors, and probably by targ...
doi.org
4 6
Reposted by Léa Monge-Waleryszak
natplants.nature.com
Nature Plants @natplants.nature.com · Aug 18
New Article: "Vacuolar sorting receptors coordinate lytic vacuolar and autophagic transport for plant effector-triggered immunity" rdcu.be/eBbOG

VSRs orchestrate the vacuolar sorting of immune-related proteins and autophagic degradation of bacterial effectors in ETI.
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Reposted by Léa Monge-Waleryszak
mesny.bsky.social
Fantin Mesny @mesny.bsky.social · Aug 15
📣 NEW PREPRINT 📝

We identified evolutionary origins of many fungal effectors!
We show that fungi secrete lots of antimicrobial proteins, and that some of them were repurposed by plant pathogens for host immune suppression.
www.biorxiv.org/content/10.1...

cc @teamthomma.bsky.social
Plant-associated fungi co-opt ancient antimicrobials for host manipulation
Evolutionary histories of effector proteins secreted by fungal pathogens to mediate plant colonization remain largely elusive. While most functionally characterized effectors modulate plant immunity, ...
www.biorxiv.org
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Reposted by Léa Monge-Waleryszak
madic.bsky.social
Marcel Dickmanns | 🌿❄️🔬 @madic.bsky.social · Jul 26
New preprint: In situ Architecture of #Plasmodesmata.

Using #cryoET, #AlphaFold & proteomics, we uncover the native organization of plant intercellular nanopores.

🔗 doi.org/10.1101/2025...

🧪🧵1/n
#teamtomo #PlantScience #Physcomitrium #Arabidopsis #cryoEM
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Reposted by Léa Monge-Waleryszak
hodgeshc.bsky.social
H. Courtney Hodges @hodgeshc.bsky.social · Jul 22
How do chromatin remodelers use #IDRs to find TF binding partners? In our new Molecular Cell paper, we show that β-catenin is an adaptor that links SWI/SNF (cBAF) subunit ARID1A with binding partners via IDR-domain interactions.
www.cell.com/molecular-ce...
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lwaleryszak.bsky.social
Léa Monge-Waleryszak @lwaleryszak.bsky.social · Jul 15
Are chromatin remodelling complexes targets of bacterial effectors PopP2 & XopJ6 ? Check out our work at #2025ISMPMI ! P-163 presented Wednesday afternoon by my amazing PhD supervisors Laurent Deslandes & Valerie Pacquit. @lipme-toulouse.bsky.social @ismpmi.bsky.social
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Reposted by Léa Monge-Waleryszak
philcarella.bsky.social
Phil Carella @philcarella.bsky.social · Apr 1
Conserved effectors underpin the virulence of liverwort-isolated Pseudomonas in divergent plants

Very happy to share the published version of our work on natural Marchantia-Pseudomonas interactions.

Out now in Current Biology: www.cell.com/current-biol...
Conserved effectors underpin the virulence of liverwort-isolated Pseudomonas in divergent plants
Robinson et al. identify pathogenic Pseudomonas viridiflava in wild Marchantia polymorpha liverworts and interrogate the mechanisms enabling virulence in non-flowering and flowering plants. Their resu...
www.cell.com
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lwaleryszak.bsky.social
Léa Monge-Waleryszak @lwaleryszak.bsky.social · May 26
Love uncovering effector virulence strategies! 😀
Our work on PopP2 targeting core components of the PEAT chromatin-remodeling complexes is now out @theplantjournal.bsky.social.
doi.org/10.1111/tpj....
Three ARID proteins involved in chromatin remodeling PEAT complexes are targeted by the Ralstonia solanacearum effector PopP2 and contribute to bacterial wilt disease
The Ralstonia solanacearum effector PopP2 is a YopJ family acetyltransferase. PopP2 is known to dampen basal immune responses by acetylating defensive WRKY transcription factors, and probably by targ...
doi.org
4 6
Reposted by Léa Monge-Waleryszak
thesainsburylab.bsky.social
The Sainsbury Laboratory @thesainsburylab.bsky.social · May 22
Direct link to review @newphyt.bsky.social

nph.onlinelibrary.wiley.com/doi/10.1111/...
Exploring the untapped potential of single‐cell and spatial omics in plant biology
Advances in single-cell and spatial omics technologies have revolutionised biology by revealing the diverse molecular states of individual cells and their spatial organization within tissues. The fie...
nph.onlinelibrary.wiley.com
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Reposted by Léa Monge-Waleryszak
maudbernoux.bsky.social
Maud Bernoux @maudbernoux.bsky.social · Mar 3
Very glad to see #HéloïseDemont PhD work online in @cp-cellreports.bsky.social! @lipme-toulouse.bsky.social #REACHteam

Downstream signaling induced by several plant Toll/interleukin-1 receptor-containing immune proteins is stable at elevated temperature: www.cell.com/cell-reports...
Downstream signaling induced by several plant Toll/interleukin-1 receptor-containing immune proteins is stable at elevated temperature
Demont et al. show that immune signaling induced by Toll/interleukin-1 receptor (TIR) domains, including EDS1 and the SA sector, is maintained at elevated temperatures (30°C), in contrast to signaling...
www.cell.com
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lwaleryszak.bsky.social
Léa Monge-Waleryszak @lwaleryszak.bsky.social · Feb 2
My PhD defense was an amazing moment. Many thanks to members of my jury for examining my work and for this very enjoyable discussion:

C. Segonzac
@ifudal.bsky.social
MH. Lebrun
B. Szurek
V. Cotelle

Huge thanks to my increadible supervisors L. Deslandes & V. Pacquit for their unfailing support.
Results presentation Annoncement of the obtention of the PhD by the president of the jury following the defense Camille Puginier (PhD since January 17th 2025) and Léa Monge-Waleryszak (PhD since January 31st 2025) Celebrations
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Reposted by Léa Monge-Waleryszak
lipme-toulouse.bsky.social
Laboratoire des Interactions Plantes, Microbes et Environnement @lipme-toulouse.bsky.social · Jan 31
[#PhD] 👩‍🎓 Today Léa Monge Waleryszak defends his PhD on "Investigating the proximal proteomes of 2 YopJ family acetyltrasferases from 2 plant vascular pathogenic bacteria"
@ifudal.bsky.social
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