mardegeus.bsky.social
Mark de Geus
@mardegeus.bsky.social
56 followers 55 following 2 posts
NWO Veni Fellow @TUDelft - (Dissociative) Bioorthogonal Chemistry | Bioconjugation | Antibody-Drug Conjugates (ADCs)
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mardegeus.bsky.social
Mark de Geus @mardegeus.bsky.social · Jun 10
Excited to see this beautiful cover art by @barthvanrossum.bsky.social, which clearly illustrates our new bioconjugation chemistry for precise antibody modification in @jacs.acspublications.org! A big thank you to all co-authors @fmp-berlin.de & Tubulis GmbH and @humboldt-foundation.de for funding!
jacs.acspublications.org
Journal of the American Chemical Society (JACS) @jacs.acspublications.org · Jun 6
On the cover of this week's #JACS: "Orthogonal Site-Specific Dual Bioconjugation of Aryl and Alkyl Thiols"

Read it here 🔗 buff.ly/FJkPjYc
#ChemSky
jacs-covers-25
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mardegeus.bsky.social
Mark de Geus @mardegeus.bsky.social · May 7
Happy to share the publication of my postdoc research in the Hackenberger lab in @jacs.acspublications.org. Privileged to have worked alongside colleagues at @fmp-berlin.de and Tubulis GmbH. A big thank you to @humboldt-foundation.de for funding this exciting project!!
pubs.acs.org/doi/10.1021/...
Orthogonal Site-Specific Dual Bioconjugation of Aryl and Alkyl Thiols
We introduce aryl thiols as nucleophiles for site-specific protein and antibody bioconjugation, which allows the orthogonal labeling of native cysteines for double modification strategies. In a high-y...
pubs.acs.org
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