Margaret Frame
@margaretframe.bsky.social
Director Institute of Genetics and Cancer, Univ of Edinburgh until end of 2024 ! Then, who knows….. 😀
Reposted by Margaret Frame
Roza Masalmeh, @margaretframe.bsky.social & co uncover a FAK–ROCK-driven mechanism that links #ExtracellularMatrix mechanical cues to the rewiring of energy #metabolism, affecting mitochondrial function and malignant behaviour.
#mitochondria #cancer
Read doi.org/10.1242/dmm....
#mitochondria #cancer
Read doi.org/10.1242/dmm....
FAK modulates glioblastoma stem cell energetics via regulation of glycolysis and glutamine oxidation
Summary: The key adhesion protein focal adhesion kinase (FAK) transduces adhesion signals to enhance glycolysis and oxidative phosphorylation in a glioblastoma stem-cell model, highlighting a…
doi.org
December 16, 2025 at 8:02 AM
Roza Masalmeh, @margaretframe.bsky.social & co uncover a FAK–ROCK-driven mechanism that links #ExtracellularMatrix mechanical cues to the rewiring of energy #metabolism, affecting mitochondrial function and malignant behaviour.
#mitochondria #cancer
Read doi.org/10.1242/dmm....
#mitochondria #cancer
Read doi.org/10.1242/dmm....
@rorycj.bsky.social hi Rory - thought this might be of interest to you, www.ukri.org/news/mrc-cen...
MRC centre to develop brain stimulation device-based therapies
A new MRC centre aims to develop brain stimulation devices to treat conditions such as Parkinson’s disease, dementia, stroke and childhood epilepsy.
www.ukri.org
June 29, 2025 at 7:34 PM
@rorycj.bsky.social hi Rory - thought this might be of interest to you, www.ukri.org/news/mrc-cen...
Reposted by Margaret Frame
Whenever you welcome guests, treat them with kindness, grace and respect. Simple as that.
February 28, 2025 at 7:36 PM
Whenever you welcome guests, treat them with kindness, grace and respect. Simple as that.
Reposted by Margaret Frame
BREAKING—FDA suddenly cancels meeting to update next season’s flu vaccines, with zero explanations. Any delays will jeopardize next year’s vaccine supply chain.
February 27, 2025 at 2:29 AM
BREAKING—FDA suddenly cancels meeting to update next season’s flu vaccines, with zero explanations. Any delays will jeopardize next year’s vaccine supply chain.
Reposted by Margaret Frame
Today's university slashing and burning is Edinburgh, where about 10% of the budget will be cut. There'll be another case every single day until UK govts actually do something. A country so stupid it actively trashes one of things it's good at and famous for.
www.bbc.com/news/article...
www.bbc.com/news/article...
Edinburgh University to seek £140m in savings
Unions said the plans would result in "devastating cuts" and called for Edinburgh University to use some of its assets instead.
www.bbc.com
February 25, 2025 at 8:41 PM
Today's university slashing and burning is Edinburgh, where about 10% of the budget will be cut. There'll be another case every single day until UK govts actually do something. A country so stupid it actively trashes one of things it's good at and famous for.
www.bbc.com/news/article...
www.bbc.com/news/article...
Reposted by Margaret Frame
Just one more comment - As a researcher from across the pond who looks at the research that American scientists produce with amazement and awe, it is nothing short of heartbreaking to see what is happening with US research.
February 8, 2025 at 1:27 PM
Just one more comment - As a researcher from across the pond who looks at the research that American scientists produce with amazement and awe, it is nothing short of heartbreaking to see what is happening with US research.
Reposted by Margaret Frame
Very glad I live in a country where the head of state can’t overrule the judiciary to pardon convicted criminals or unilaterally withdraw the country from international organisations. What a ridiculous political system.
January 21, 2025 at 11:50 PM
Very glad I live in a country where the head of state can’t overrule the judiciary to pardon convicted criminals or unilaterally withdraw the country from international organisations. What a ridiculous political system.