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Mark Rossi

@markrossi.bsky.social

470 followers 270 following 15 posts

Neuroscientist studying brain control of motivation and obesity. markrossilab.org

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Mark Rossi @markrossi.bsky.social · Jul 14

The posting is now live. Apply today to join our group as a research assistant. Perfect for a recent grad looking to go to grad/med school. Message me for more info. Apply here: jobs.rutgers.edu/postings/256...

Mark Rossi @markrossi.bsky.social · 24d

🚨 New preprint from an ongoing collaboration with the Pang lab. Project led by rising stars @rohansavani.bsky.social and @lewang1.bsky.social showing how individual GLP-1R neurons in the paraventricular hypothalamus track ingestion across energy states.

Preprint: papers.ssrn.com/sol3/papers....

Individual Paraventricular Hypothalamic GLP-1R Neurons Track Ingestion Across Energy States

Energy homeostasis is tightly regulated to ensure metabolic health in the face of uncertain environments. Changes in energy states or circulating hormonal signa

papers.ssrn.com

Mark Rossi @markrossi.bsky.social · Jul 14

The posting is now live. Apply today to join our group as a research assistant. Perfect for a recent grad looking to go to grad/med school. Message me for more info. Apply here: jobs.rutgers.edu/postings/256...

Reposted by Mark Rossi

Lex Kravitz @kravitzlab.com · Jun 19

This was a really fun project: We blocked obesity in mice by making them do a tiny bit of work for their food. www.sciencedirect.com/science/arti...

A simple action reduces high-fat diet intake and obesity in mice

Diets that are high in fat cause overeating and weight gain in multiple species of animals, suggesting that high dietary fat is sufficient to cause ob…

www.sciencedirect.com

Mark Rossi @markrossi.bsky.social · Jun 16

We are hiring a new research assistant! Official job post to follow. Please reach out or visit markrossilab.org if you are interested.

Mark Rossi @markrossi.bsky.social · Jun 10

A nice write up about the new work coming out of the Rutgers Center for NeuroMetabolism www.rutgers.edu/news/two-rut...

Two Rutgers Teams Trace Brain Circuits That Tell Us When to Eat – and When to Stop

Back-to-back studies map complementary hunger and satiety pathways, offering clues to refine weight-loss drugs.

www.rutgers.edu

Reposted by Mark Rossi

Rhiana Simon, PhD @rhianasimon.bsky.social · May 16

Thrilled to announce that our paper is now finally out! 🎉We combine scRNAseq, 2p imaging, ephys, and behavior to understand the role of lateral septal Nts neurons in opioid withdrawal. Curious about the septum and addiction? Give it a read👇

www.cell.com/neuron/fullt...

Opioid-driven disruption of the septum reveals a role for neurotensin-expressing neurons in withdrawal

Opioid withdrawal produces a dysphoric state that can lead to relapse. Simon et al. reveal that lateral septal neurotensin-expressing neurons are selectively activated by naloxone and drive changes in...

Mark Rossi @markrossi.bsky.social · May 14

This was a team effort from everyone in the lab. A huge thank you to all involved. The project was made possible by generous support from the NIH.
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Mark Rossi @markrossi.bsky.social · May 14

These processes are influenced by hunger and satiety hormones, which modulate the BNST→LHA pathway to align food-seeking behavior with current energy needs.
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Mark Rossi @markrossi.bsky.social · May 14

We found that synaptic strength and neuronal function within this pathway are dynamically regulated based on the animal’s energy state, guiding reward-seeking behavior accordingly.
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Mark Rossi @markrossi.bsky.social · May 14

Using a combination of optogenetics, in vivo 2p calcium imaging, and electrophysiology, we show that the BNST→LHA pathway promotes reward seeking in an energy state-dependent manner.
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Mark Rossi @markrossi.bsky.social · May 14

We focused on the GABAergic pathway from the bed nucleus of the stria terminalis (BNST) to glutamatergic neurons of the lateral hypothalamic area (LHA), specifically examining how this circuit modulates reward-seeking behavior based on energy state.
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Mark Rossi @markrossi.bsky.social · May 14

Excited to share our latest paper led by Kuldeep Shrivastava out now in @natcomms.nature.com
www.nature.com/articles/s41...
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Energy state guides reward seeking via an extended amygdala to lateral hypothalamus pathway - Nature Communications

The lateral hypothalamic area (LHA) mediates reward seeking. Here, the authors show how LHA afferent connections promote reward seeking by shaping synaptic strength according to energy state, processe...

Mark Rossi @markrossi.bsky.social · Apr 12

The new Rutgers Center for NeuroMetabolism is officially hiring faculty at all levels! Come be my colleague!

jobs.rutgers.edu/postings/248...

Assistant/Associate/Full Professor

The newly launched Rutgers Center for NeuroMetabolism (CNM), in collaboration with the Child Health Institute of New Jersey (CHINJ), the Department of Neuroscience and Cell Biology (NCB), and the Rutg...

jobs.rutgers.edu

Mark Rossi @markrossi.bsky.social · Mar 12

Now is a great time to support basic research. Consider making a donation to the newly established Rutgers Center for Neurometabolism for giving day. Donations will support our wonderful trainees as they navigate a challenging funding landscape give.rutgersfoundation.org/neurometabol...

RWJMS Center for NeuroMetabolism Research Fund | Support Rutgers University Foundationlabel.header.loginSubmit search keywordsSubmit search keywordsView CartView CartsearchView CartSubmit search keywo...

The Rutgers Center for NeuroMetabolism (CNM), a division of the Child Health Institute of New Jersey, is a world-renowned leader in researching the neurological aspects of metabolic health and disease...

give.rutgersfoundation.org

Mark Rossi @markrossi.bsky.social · Mar 5

Big things happening at the new Rutgers Center for NeuroMetabolism! www.rutgers.edu/news/rutgers...

Rutgers Launches Center to Tackle Barriers to Weight Loss and Other Causes of Disease

www.rutgers.edu

Mark Rossi @markrossi.bsky.social · Mar 3

There's still time to apply. Come present your work at Rutgers!

Mark Rossi @markrossi.bsky.social · Feb 7

The Brain Health Institute at Rutgers is hosting a postdoc recruitment event April 22-23. Grad students and postdocs looking for postdoc positions, apply today to present your work, network with colleagues, and connect with potential mentors. brainhealthinstitute.rutgers.edu/2025-bhi-pos...

2025 BHI Postdoc Recruitment Event - BHI

brainhealthinstitute.rutgers.edu

Mark Rossi @markrossi.bsky.social · Feb 7

The Brain Health Institute at Rutgers is hosting a postdoc recruitment event April 22-23. Grad students and postdocs looking for postdoc positions, apply today to present your work, network with colleagues, and connect with potential mentors. brainhealthinstitute.rutgers.edu/2025-bhi-pos...

2025 BHI Postdoc Recruitment Event - BHI

brainhealthinstitute.rutgers.edu

Reposted by Mark Rossi

John Speakman @johnspeakman4.bsky.social · Dec 4

PhD or post doc? attending a meeting about metabolism in 2025? Need some financial support? Consider applying for one of these travel grants from @lifemetabolism.bsky.social 750 US$ for a half page application.

Life Metabolism @lifemetabolism.bsky.social · Dec 2

Win our Travel Prize for 2025 meetings！Learn more: academic.oup.com/lifemeta/pag...

Are you a PhD student or a postdoc fellow working on metabolism? Are you intending to present a talk or poster at an upcoming conference during 2025? Do you nee

academic.oup.com

Reposted by Mark Rossi

Randy J Seeley @seeleyrj.bsky.social · Dec 4

Latest from our group in collaboration with Lotte Bjerre Knudsen and other Novo scientists. They developed a GLP-1/Leptin co-agonist that we put through its paces in a number of mouse models to prove that both parts of the molecule matter. More options on the table!
www.science.org/doi/10.1126/...

Glp1r-Lepr coexpressing neurons modulate the suppression of food intake and body weight by a GLP-1/leptin dual agonist

Orthogonal murine models demonstrate the bioactivity and neuronal targets of a GLP-1/leptin coagonist in relation to food intake and body weight.

www.science.org

Reposted by Mark Rossi

Mike Krashes @mikekrashes.bsky.social · Dec 3

New work stemming from an amazing collaboration with @addisonwebster0 and @AUGCsoup using a combination of rabies mapping and single cell sequencing to identify a GLP1R-expressing local input to AgRP cells that curbs appetite rdcu.be/d2gB5

Molecular connectomics reveals a glucagon-like peptide 1-sensitive neural circuit for satiety

Nature Metabolism - Combining rabies-based connectomics with single-nucleus transcriptomics, the authors identify a neural circuit through which GLP-1 receptor agonists suppress appetite in mice.

Reposted by Mark Rossi

Tibor Rohacs @rohacstibor.bsky.social · Nov 29

The deadline to apply to our Cell Biology, Neuroscience and Physiology (CBNP) PhD program is January 3 for in person interviews. Better to apply earlier as in person slots tend to fill up sooner.
njms.rutgers.edu/sgs/prospect...

Reposted by Mark Rossi

Staci Bilbo @sbilbo.bsky.social · Nov 19

Excited to share my contribution to this free to all, open access Behavioral Neuroscience textbook including the FIRST EVER Neuroimmunology chapter! please share and let us know what you think.

Dr. Liz Kirby @thekirbylab.bsky.social · Nov 15

Announcing a new open access textbook for entry level behavioral neuro. Funded by NSF. Written by a collection of 26 neuro experts. Method demonstration videos and author interviews too. Consider using it in your courses to reduce financial barriers to education.

openstax.org/details/book...

Picture of textbook cover with title "Introduction to Behavioral Neuroscience"

Reposted by Mark Rossi

Shelly Flagel @flagel-lab.bsky.social · Nov 18

OPEN RANK #FACULTY #POSITION in #Pharmacology & #Neuroscience with expertise in #behavioral pharmacology/neuroscience of relevance to substance use disorders. Review of applications will start immediately. Target start date is Fall 2025. Come join us!

Apply here: careers.umich.edu/job_detail/2...

Professor / Associate Professor / Assistant Professor | U-M Careers

careers.umich.edu