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Massive Photonics @massivephotonics.bsky.social · 14d

Why our DNA-PAINT Halo Kits?
✔️ Ultra-precise labeling with small single-domain antibodies (~15 kDa)
✔️ Full compatibility with the Halo system - no interference with Halo-ligand binding
✔️ Unmatched resolution with DNA-PAINT (10–20 nm)
✔️ Seamless integration into existing super-resolution workflows

Massive Photonics @massivephotonics.bsky.social · 14d

⭐ Anti-Halo single-domain antibodies licensed from @nanotag.bsky.social, where they’re available unmodified and fluorophore-coupled.

🧬 Curious about starting DNA-PAINT super-resolution microscopy? Reach out: [email protected]

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Massive Photonics @massivephotonics.bsky.social · 14d

🧬 𝗡𝗲𝘄 𝗣𝗿𝗼𝗱𝘂𝗰𝘁 𝗟𝗮𝘂𝗻𝗰𝗵! 🧬The highly-requested 𝗮𝗻𝘁𝗶-𝗛𝗮𝗹𝗼 𝗗𝗡𝗔-𝗣𝗔𝗜𝗡𝗧 𝗸𝗶𝘁 is finally here!
Reveal nanoscale organization of Halo-tagged proteins with our plug-and-play DNA-PAINT kit.

🔗Learn More: www.massive-photonics.com/product-cate...

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Massive Photonics @massivephotonics.bsky.social · 20d

💡 𝗣𝗿𝗼 𝗧𝗶𝗽: For maximum resolution use imager dye 𝗖𝘆𝟯𝗕.

Speed or resolution: which will drive your next discovery?

Massive Photonics @massivephotonics.bsky.social · 20d

𝗦𝘁𝗮𝗻𝗱𝗮𝗿𝗱 𝘀𝗲𝗾𝘂𝗲𝗻𝗰𝗲𝘀 (in DNA-PAINT Kits)
🔹 Resolution: ~20 nm
🔹 Imaging time: 30–60 min/target
🔹 Exposure: 150–250 ms
👉 Compatible with 𝗠𝗜𝗡𝗙𝗟𝗨𝗫 𝗗𝗡𝗔-𝗣𝗔𝗜𝗡𝗧

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Massive Photonics @massivephotonics.bsky.social · 20d

𝗙𝗔𝗦𝗧-𝗟𝗕 𝘀𝗲𝗾𝘂𝗲𝗻𝗰𝗲𝘀 (option in FAST Kits)
🔹 Resolution: ~10 nm
🔹 Imaging time: 10–30 min/target
🔹 Exposure: 100–150 ms
👉 Best for 𝗵𝗶𝗴𝗵𝗲𝘀𝘁 𝗿𝗲𝘀𝗼𝗹𝘂𝘁𝗶𝗼𝗻
👉 Compatible with 𝗠𝗜𝗡𝗙𝗟𝗨𝗫 𝗗𝗡𝗔-𝗣𝗔𝗜𝗡𝗧

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Massive Photonics @massivephotonics.bsky.social · 20d

𝗙𝗔𝗦𝗧 𝘀𝗲𝗾𝘂𝗲𝗻𝗰𝗲𝘀 (option in FAST Kits)
🔹 Resolution: ~15 nm
🔹 Imaging time: 5–15 min/target
🔹 Exposure: 30–75 ms
👉 Best for 𝗳𝗮𝘀𝘁𝗲𝗿 𝗶𝗺𝗮𝗴𝗶𝗻𝗴

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Massive Photonics @massivephotonics.bsky.social · 20d

🔬 𝗪𝗵𝗶𝗰𝗵 𝗗𝗡𝗔-𝗣𝗔𝗜𝗡𝗧 𝘀𝗲𝗾𝘂𝗲𝗻𝗰𝗲 𝗶𝘀 𝗿𝗶𝗴𝗵𝘁 𝗳𝗼𝗿 𝘆𝗼𝘂?
Our #DNAPAINT Labeling Kits let you choose the balance of 𝘀𝗽𝗲𝗲𝗱 𝗮𝗻𝗱 𝗿𝗲𝘀𝗼𝗹𝘂𝘁𝗶𝗼𝗻 that fits your research.

⭐DNA-PAINT kits: www.massive-photonics.com/product-cate...
⭐FAST DNA-PAINT kits: www.massive-photonics.com/product-cate...

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Massive Photonics @massivephotonics.bsky.social · 20d

💡 𝗣𝗿𝗼 𝗧𝗶𝗽: For maximum resolution use imager dye 𝗖𝘆𝟯𝗕.

Speed or resolution: which will drive your next discovery?

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Massive Photonics @massivephotonics.bsky.social · 20d

✨ 𝗦𝘁𝗮𝗻𝗱𝗮𝗿𝗱 𝘀𝗲𝗾𝘂𝗲𝗻𝗰𝗲𝘀 (in DNA-PAINT Kits)
🔹 Resolution: ~20 nm
🔹 Imaging time: 30–60 min/target
🔹 Exposure: 150–250 ms
👉 Compatible with 𝗠𝗜𝗡𝗙𝗟𝗨𝗫 𝗗𝗡𝗔-𝗣𝗔𝗜𝗡𝗧

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Massive Photonics @massivephotonics.bsky.social · 20d

✨ 𝗙𝗔𝗦𝗧-𝗟𝗕 𝘀𝗲𝗾𝘂𝗲𝗻𝗰𝗲𝘀 (option in FAST Kits)
🔹 Resolution: ~10 nm
🔹 Imaging time: 10–30 min/target
🔹 Exposure: 100–150 ms
👉 Best for 𝗵𝗶𝗴𝗵𝗲𝘀𝘁 𝗿𝗲𝘀𝗼𝗹𝘂𝘁𝗶𝗼𝗻
👉 Compatible with 𝗠𝗜𝗡𝗙𝗟𝗨𝗫 𝗗𝗡𝗔-𝗣𝗔𝗜𝗡𝗧

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Massive Photonics @massivephotonics.bsky.social · 20d

✨ 𝗙𝗔𝗦𝗧 𝘀𝗲𝗾𝘂𝗲𝗻𝗰𝗲𝘀 (option in FAST Kits)
🔹 Resolution: ~15 nm
🔹 Imaging time: 5–15 min/target
🔹 Exposure: 30–75 ms
👉 Best for 𝗳𝗮𝘀𝘁𝗲𝗿 𝗶𝗺𝗮𝗴𝗶𝗻𝗴

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Massive Photonics @massivephotonics.bsky.social · 27d

🤔 Not sure where to start? Email us at [email protected]

anti-ALFA single-domain antibodies licensed from @nanotag.bsky.social where it's available unmodified and fluorophore-coupled

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Massive Photonics @massivephotonics.bsky.social · 27d

The 𝗔𝗟𝗙𝗔-𝘁𝗮𝗴 𝗶𝘀 𝗮 𝘀𝗺𝗮𝗹𝗹 𝗿𝗮𝘁𝗶𝗼𝗻𝗮𝗹𝗹𝘆 𝗱𝗲𝘀𝗶𝗴𝗻𝗲𝗱 𝗽𝗿𝗼𝘁𝗲𝗶𝗻 𝘁𝗮𝗴 that facilitates highly specific labeling when combined with the anti-ALFA single-domain antibody (rdcu.be/eFy86 ).

The ALFA-tag is a highly versatile tool for nanobody-based bioscience applications

Nature Communications - Epitope tags are widely used in various applications, but often lack versatility. Here, the authors introduce a small, alpha helical tag, which is recognized by a high...

rdcu.be

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Massive Photonics @massivephotonics.bsky.social · 27d

𝗥𝗘𝗦𝗜 𝗶𝘀 𝗮 𝗗𝗡𝗔-𝗣𝗔𝗜𝗡𝗧 𝗯𝗮𝘀𝗲𝗱 𝗺𝗲𝘁𝗵𝗼𝗱 that achieves sub-nanometer spatial-resolution in cells, enabling precise imaging of individual proteins (rdcu.be/eFy7c).

Ångström-resolution fluorescence microscopy

Nature - The authors introduce a single-molecule DNA-barcoding method, resolution enhancement by sequential imaging, that improves the resolution of fluorescence microscopy down to the...

rdcu.be

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Massive Photonics @massivephotonics.bsky.social · 27d

🔬 𝗢𝘂𝗿 𝗥𝗘𝗦𝗜 𝗞𝗶𝘁𝘀 𝗱𝗲𝗹𝗶𝘃𝗲𝗿:
✔️ Single-protein resolution even in dense formations like dimers and clusters
✔️ Full field-of-view imaging for robust statistics and whole-cell investigations
✔️ Compatibility with widefield-TIRF and commercial SMLM microscopes

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Massive Photonics @massivephotonics.bsky.social · 27d

🚀 New Product Launch! 🚀
Ready to push your imaging to 𝘀𝘂𝗯-𝗻𝗮𝗻𝗼𝗺𝗲𝘁𝗲𝗿 𝘀𝗽𝗮𝘁𝗶𝗮𝗹 𝗿𝗲𝘀𝗼𝗹𝘂𝘁𝗶𝗼𝗻? Introducing our newest 𝗥𝗘𝗦𝗜 𝗞𝗶𝘁 𝗳𝗼𝗿 𝗔𝗟𝗙𝗔-𝘁𝗮𝗴𝗴𝗲𝗱 𝗽𝗿𝗼𝘁𝗲𝗶𝗻𝘀!
🔗 www.massive-photonics.com/product-cate...

#SMLM #RESI #DNAPAINT #Microscopy #nuclearpore

DNA-PAINT and RESI imaging of ALFA-tagged nuclear pore protein Nup96 using the RESI anti-ALFA kit. For RESI imaging, four Exchange-PAINT rounds were performed using a mixture of anti-ALFA single-domain antibodies carrying docking strands F1, F2, F3, and F4 (10,000 frames per round,100 ms integration time, ~ 80 min total imaging time). Image post-processing was carried out using the open-source DNA-PAINT analysis software Picasso's RESI module.
For classic DNA-PAINT, all four imager strands were added to the sample simultaneously.

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Massive Photonics @massivephotonics.bsky.social · Sep 4

Start revealing cellular structures with nanoscale precision today!

#SMLM #Microscopy #DNAPAINT #MassivePhotonics

Massive Photonics @massivephotonics.bsky.social · Sep 4

🔬 DNA-PAINT is compatible with widefield-TIRF and commercial SMLM microscopes
💻 Analyze your data with SMLM software or the open-source Picasso toolkit (www.biochem.mpg.de/jungmann/sof...)

👉 www.massive-photonics.com/technology/

DNA-PAINT Labeling Kits for Super-Resolution Imaging

Massive-Photonics offers ready-to-use labelling kits for DNA-PAINT based super-resolution imaging.

massive-photonics.com

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Massive Photonics @massivephotonics.bsky.social · Sep 4

🚀 New to DNA-PAINT? We make getting started simple.

Check out our 𝗽𝗹𝘂𝗴-𝗮𝗻𝗱-𝗽𝗹𝗮𝘆 #DNAPAINT 𝗹𝗮𝗯𝗲𝗹𝗶𝗻𝗴 𝗮𝗻𝗱 𝗶𝗺𝗮𝗴𝗶𝗻𝗴 𝗸𝗶𝘁𝘀:
✅ Seamless integration into immunostaining workflows
✅ Wide range of kits designed for various targets
✅ Includes all labeling & imaging reagents needed

🔗 massive-photonics.com

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Massive Photonics @massivephotonics.bsky.social · Aug 28

📢 Don’t forget to stop by our booth at #SMLMS2025!

We’re excited to share how our #DNAPAINT solutions and labeling kits can help you unlock nanoscale insights 🔬🧬

📍WP Building Foyer, near the windows

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Massive Photonics @massivephotonics.bsky.social · Aug 25

📢 We're heading to Single Molecule Localization Microscopy Symposium 2025 in Bonn!

📍 Stop by our booth in the foyer of the WP building to say hello and discuss how our DNA-PAINT kits and solutions enable multiplexed nanoscale imaging.

#SMLM #SMLMS2025 #DNAPAINT

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Massive Photonics @massivephotonics.bsky.social · Aug 7

🧬 DNA-PAINT is compatible with widefield-TIRF and standard SMLM microscopes. Analyze your data using SMLM software or dive in with the open-source DNA-PAINT analysis tool, Picasso.

🤔 Don’t know where to start? Request a consultation via [email protected]

Massive Photonics @massivephotonics.bsky.social · Aug 7

Kits available for:
⭐ Mouse kLc, IgG2a/b, IgG1, IgG
⭐ Rabbit IgG
⭐ Rat IgG
⭐ Human IgG
⭐ Goat IgG
⭐ Guinea pig IgG
⭐ Custom requests

Kits using secondary sdABs (single-domain antibodies) licensed from @nanotag.bsky.social, where they're available unmodified and fluorophore-coupled.

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Massive Photonics @massivephotonics.bsky.social · Aug 7

I𝗺𝗺𝘂𝗻𝗼𝗹𝗮𝗯𝗲𝗹𝗶𝗻𝗴 𝘆𝗼𝘂𝗿 𝘀𝗮𝗺𝗽𝗹𝗲𝘀 𝘂𝘀𝗶𝗻𝗴 𝗽𝗿𝗶𝗺𝗮𝗿𝘆 𝗮𝗻𝘁𝗶𝗯𝗼𝗱𝗶𝗲𝘀? Take your imaging to nanoscale resolution with our 𝗽𝗹𝘂𝗴-𝗮𝗻𝗱-𝗽𝗹𝗮𝘆 𝗗𝗡𝗔-𝗣𝗔𝗜𝗡𝗧 𝘀𝗲𝗰𝗼𝗻𝗱𝗮𝗿𝘆 𝗯𝗶𝗻𝗱𝗲𝗿 𝗸𝗶𝘁𝘀.

🔗 www.massive-photonics.com/product-cate...

#DNAPAINT #SuperResolution #SMLM #Microscopy

DNA-PAINT samples/images generated using our secondary binder kits:
🔹 Paxillin & Vimentin – Massive-sdAB-FAST 2-Plex Kit
🔹 Tom20 & HSP60 – Massive-AB 2-Plex Kit
🔹 Tom20 – Massive-sdAB 1-Plex Kit
🔹 Tubulin –= Massive-sdAB-FAST 1-Plex Kit
AB = antibody | sdAB = single-domain antibody

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