The Matile Group
@matilegroup.bsky.social
1.2K followers 110 following 22 posts
Supramolecular Systems (th)at Work www.unige.ch/sciences/chiorg/matile/
Posts Media Videos Starter Packs
matilegroup.bsky.social
In our new paper in Chem. Sci., we show that the replacement of one oxygen by one sulfur atom in phospholipids affords phosphorothioate liposomes that penetrate cells by thiol-mediated uptake in intact form and with contributions neither from fusion nor from endocytosis.
matilegroup.bsky.social
Congratulations for an intriguing PhD defence and very best wishes to Dr. Michael Cognet for a great future.

A big thank you to the members of the jury, Kurt Gothelf, Nicolas Winssinger and Clement Mazet.
matilegroup.bsky.social
Our new paper in Angew. Chem. introduces an enabling method to make catalysis with externally applied electric fields compatible with organic synthesis.

onlinelibrary.wiley.com/doi/10.1002/...
matilegroup.bsky.social
For a great start into the new academic year, we climbed up to the largest glacier in the Alps, a UNESCO World Heritage Site.
matilegroup.bsky.social
This invited commentary in Angew. Chem. highlights the importance of translational supramolecular chemistry, and the power of the big yellow sulfur atom in this context, despite its diabolic reputation.

onlinelibrary.wiley.com/doi/10.1002/...
matilegroup.bsky.social
Our new paper in Helv. Chim. Acta, the Journal of the Swiss Chemical Society, founded 1917, elaborates on unorthodox reversible Michael addition for cellular uptake; with the groups of @tbpoulsen.bsky.social‬ and @oliverthornseshold.bsky.social‬.

onlinelibrary.wiley.com/doi/10.1002/...
matilegroup.bsky.social
552 flippers and a few crabs, what a cover, please enjoy

Thank you, JACS Au: pubs.acs.org/doi/10.1021/...
matilegroup.bsky.social
Thank you so much for reading: Our new paper on photocatalytic microenvironment proteomics of thiol-mediated uptake still hangs on in the top 20 of JACS Au. It aims to give a better understanding of a process that might be more important than we all expected.

pubs.acs.org/doi/10.1021/...
matilegroup.bsky.social
Many thanks for your interest: The essence are sigma-hole interactions, chalcogen bonds, which cause the twisting and produce a push-pull system upon planarization.
matilegroup.bsky.social
In our new paper in JACS Au, with the Sagara group from the Institute of Science Tokyo, we introduce flippers than respond to stretching rather than compression and applicability to the materials rather than the life sciences (GOA).

pubs.acs.org/doi/10.1021/...
matilegroup.bsky.social
Photocatalytic microenvironment proteomics identifies proteins in thiol-mediated uptake by covalent labeling without disturbing exchange network dynamics. We hope our new paper will help the community to better understand, explore and use this enigmatic process.

pubs.acs.org/doi/10.1021/...
matilegroup.bsky.social
Violating the EDB rules, access to intrinsically disfavored products increases with increasing electric fields applied to electromicrofluidic reactors with carbon nanotubes (besides conversion going from 0 to 100%).

Now new in Chem. Sci., pubs.rsc.org/en/content/a..., Diamond Open Access, RSC
matilegroup.bsky.social
Thank you very much for highlighting our paper
chemicalscience.rsc.org
This week's #ChemSciPicks comes from @matilegroup.bsky.social (University of Geneva, Switzerland), who look at the response of reaction mechanisms to electric-field catalysis on carbon nanotubes in microfluidic reactors. Read the full paper here: pubs.rsc.org/doi/D5S...
matilegroup.bsky.social
Congratulations to Filipe Coelho for a great PhD defense, on uptake exchange partners, integrins, PDIs, cell motility, selenenylsulfides, and more. Many thanks for all and very best wishes for a bright future.

Special thanks also to jury members, specially C. Hackenberger, who came from far.
matilegroup.bsky.social
The intro:

Up springs the spout and, falling, fills
To brim the marble basin’s round,
Which, under veiling, over spills
Into a second basin’s ground;
The second one, too rich now, runs
Into the third its falling waves,
And each one takes and gives at once
And streams and stays.

C. F. Meyer
matilegroup.bsky.social
An update on dynamic covalent cascade exchange chemistry, thiol-mediated uptake and the CH-ERC AdG TIMEUP, now new in Chimia, the POA Journal of the Swiss Chemical Society.

www.chimia.ch/chimia/artic...
matilegroup.bsky.social
We have about 2-4 postdoc positions available per year, applications are welcome anytime, please see www.unige.ch/sciences/chi...
matilegroup.bsky.social
Congratulations, Angie - Dr. Gutiérrez-López

for an excellent PhD defense on “Microfluidic Electric-Field Catalysis on Carbon Nanotubes and the Origin of Anion-π Autocatalysis”

A big thank you for all and best wishes for the future!

Many thanks also to the jury, M. Prato, C. Mazet, J. Lacour
matilegroup.bsky.social
Hello #ChemSky, we are a research group in Geneva, Switzerland, interested in translating principles from supramolecular chemistry to address significant challenges at the interface of organic chemistry, chemical biology and materials.