The Molecular Biology Society of Japan (MBSJ)
@mbsj-official.bsky.social
Official account of The Molecular Biology Society of Japan (MBSJ).
日本分子生物学会の公式アカウントです。
MBSJ Website:
EN https://www.mbsj.jp/en/
JP https://www.mbsj.jp/
日本分子生物学会の公式アカウントです。
MBSJ Website:
EN https://www.mbsj.jp/en/
JP https://www.mbsj.jp/
Genes to Cells
Volume 30, Issue 6, 2025.
"Removing Extracellular Matrix From the Cell Surface Prior to Seeding Enhances the Adhesion of Primary Human Hepatocytes to the Culture Vessel"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 6, 2025.
"Removing Extracellular Matrix From the Cell Surface Prior to Seeding Enhances the Adhesion of Primary Human Hepatocytes to the Culture Vessel"
doi.org/10.1111/gtc....
Author's Comment ➡️
Removing Extracellular Matrix From the Cell Surface Prior to Seeding Enhances the Adhesion of Primary Human Hepatocytes to the Culture Vessel
The variable adhesiveness of primary human hepatocytes to culture vessels limits their utility. We demonstrate that removing the extracellular matrix from the cell surface (denudation) enables suspen...
doi.org
December 16, 2025 at 1:40 AM
Genes to Cells
Volume 30, Issue 6, 2025.
"Removing Extracellular Matrix From the Cell Surface Prior to Seeding Enhances the Adhesion of Primary Human Hepatocytes to the Culture Vessel"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 6, 2025.
"Removing Extracellular Matrix From the Cell Surface Prior to Seeding Enhances the Adhesion of Primary Human Hepatocytes to the Culture Vessel"
doi.org/10.1111/gtc....
Author's Comment ➡️
Genes to Cells
Volume 30, Issue 6, 2025.
"Quantitative Imaging Analysis of Internal Structural Complexity in Mouse Heart Organoids; Comparison to Mouse Embryonic Hearts"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 6, 2025.
"Quantitative Imaging Analysis of Internal Structural Complexity in Mouse Heart Organoids; Comparison to Mouse Embryonic Hearts"
doi.org/10.1111/gtc....
Author's Comment ➡️
Quantitative Imaging Analysis of Internal Structural Complexity in Mouse Heart Organoids; Comparison to Mouse Embryonic Hearts
Illustration of the proposed machine learning model for analyzing the internal structures of mouse embryonic hearts and mouse heart organoids (mHOs). The autofluorescence images of tissue-cleared E11....
doi.org
December 16, 2025 at 1:38 AM
Genes to Cells
Volume 30, Issue 6, 2025.
"Quantitative Imaging Analysis of Internal Structural Complexity in Mouse Heart Organoids; Comparison to Mouse Embryonic Hearts"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 6, 2025.
"Quantitative Imaging Analysis of Internal Structural Complexity in Mouse Heart Organoids; Comparison to Mouse Embryonic Hearts"
doi.org/10.1111/gtc....
Author's Comment ➡️
Genes to Cells
Volume 30, Issue 6, 2025.
"An Upstream RUNX3 Enhancer, eR3 (-18m/-28h), Regulates the Development of Gut-Associated Anti-Tumorigenic CD8+CD103+ Cytotoxic T Lymphocytes in Mouse and Human"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 6, 2025.
"An Upstream RUNX3 Enhancer, eR3 (-18m/-28h), Regulates the Development of Gut-Associated Anti-Tumorigenic CD8+CD103+ Cytotoxic T Lymphocytes in Mouse and Human"
doi.org/10.1111/gtc....
Author's Comment ➡️
An Upstream RUNX3 Enhancer, eR3 (−18m/−28h), Regulates the Development of Gut‐Associated Anti‐Tumorigenic CD8+CD103+ Cytotoxic T Lymphocytes in Mouse and Human
(A) Numbers of spleen CD8+ T cells and CD8+ intraepithelial lymphocytes (IEL) and their anti-tumor function are affected in eR3−/− and Runx3−/− mice. (B) In human individuals with SNP in eR3, CD8+ CD...
doi.org
December 16, 2025 at 1:34 AM
Genes to Cells
Volume 30, Issue 6, 2025.
"An Upstream RUNX3 Enhancer, eR3 (-18m/-28h), Regulates the Development of Gut-Associated Anti-Tumorigenic CD8+CD103+ Cytotoxic T Lymphocytes in Mouse and Human"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 6, 2025.
"An Upstream RUNX3 Enhancer, eR3 (-18m/-28h), Regulates the Development of Gut-Associated Anti-Tumorigenic CD8+CD103+ Cytotoxic T Lymphocytes in Mouse and Human"
doi.org/10.1111/gtc....
Author's Comment ➡️
Genes to Cells
Volume 30, Issue 6, 2025.
"Decreased Mitochondrial Translation Suppresses 3,3′-Diindolylmethane-Induced Reactive Oxygen Species Generation in Schizosaccharomyces Pombe"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 6, 2025.
"Decreased Mitochondrial Translation Suppresses 3,3′-Diindolylmethane-Induced Reactive Oxygen Species Generation in Schizosaccharomyces Pombe"
doi.org/10.1111/gtc....
Author's Comment ➡️
Decreased Mitochondrial Translation Suppresses 3,3′‐Diindolylmethane‐Induced Reactive Oxygen Species Generation in Schizosaccharomyces Pombe
3,3′-diindolylmethane induces growth defects by increasing ROS levels in mitochondria, which are suppressed via inhibition of mitochondrial translation in Schizosaccharomyces pombe. The study highlig...
doi.org
December 16, 2025 at 1:31 AM
Genes to Cells
Volume 30, Issue 6, 2025.
"Decreased Mitochondrial Translation Suppresses 3,3′-Diindolylmethane-Induced Reactive Oxygen Species Generation in Schizosaccharomyces Pombe"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 6, 2025.
"Decreased Mitochondrial Translation Suppresses 3,3′-Diindolylmethane-Induced Reactive Oxygen Species Generation in Schizosaccharomyces Pombe"
doi.org/10.1111/gtc....
Author's Comment ➡️
【NEWS】Announcement for the International Workshop on Bacterial Flagella and BioMachinery www.mbsj.jp/en/ads/meeti...
Related Meetings - MBSJ: The Molecular Biology Society of Japan
www.mbsj.jp
December 1, 2025 at 8:28 AM
【NEWS】Announcement for the International Workshop on Bacterial Flagella and BioMachinery www.mbsj.jp/en/ads/meeti...
【NEWS】Postdoctoral Fellow Position in Regenerative Biology and Extreme Physiology University of California San Francisco, San Francisco, USA
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November 14, 2025 at 7:40 AM
【NEWS】Postdoctoral Fellow Position in Regenerative Biology and Extreme Physiology University of California San Francisco, San Francisco, USA
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【NEWS】 Postdoctoral Position, Thomas Jefferson University Sidney Kimmel Medical College
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November 10, 2025 at 8:41 AM
【NEWS】 Postdoctoral Position, Thomas Jefferson University Sidney Kimmel Medical College
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【NEWS】 The Meeting for Advanced Synthetic Biology and Systems Bioengineering in Vancouver (MASSIV 1.0)
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October 28, 2025 at 6:46 AM
【NEWS】 The Meeting for Advanced Synthetic Biology and Systems Bioengineering in Vancouver (MASSIV 1.0)
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【NEWS】 RIKEN BDR Symposium 2026: Calling for participants & presenters!
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October 24, 2025 at 9:05 AM
【NEWS】 RIKEN BDR Symposium 2026: Calling for participants & presenters!
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Genes to Cells
Volume 30, Issue 5, 2025.
"Knockdown of Cav2.2 Calcium Channel in Macrophages Aggravates Colitis Induced by Dextran Sodium Sulfate"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 5, 2025.
"Knockdown of Cav2.2 Calcium Channel in Macrophages Aggravates Colitis Induced by Dextran Sodium Sulfate"
doi.org/10.1111/gtc....
Author's Comment ➡️
Knockdown of Cav2.2 Calcium Channel in Macrophages Aggravates Colitis Induced by Dextran Sodium Sulfate
Cav2.2KD mice are transgenic mice, where Cav2.2 expression is suppressed in macrophages by RNAi. Dextran sodium sulfate (DSS)—induced colitis was more severe in Cav2.2KD mice, with larger accumulatio...
doi.org
October 10, 2025 at 1:51 AM
Genes to Cells
Volume 30, Issue 5, 2025.
"Knockdown of Cav2.2 Calcium Channel in Macrophages Aggravates Colitis Induced by Dextran Sodium Sulfate"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 5, 2025.
"Knockdown of Cav2.2 Calcium Channel in Macrophages Aggravates Colitis Induced by Dextran Sodium Sulfate"
doi.org/10.1111/gtc....
Author's Comment ➡️
Genes to Cells
Volume 30, Issue 5, 2025.
"Transcriptional Regulation of the Interferon Alpha-Inducible Protein-27 Like 2b by the Peroxisome Proliferator-Activated Receptor γ in Fatty Liver Disease"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 5, 2025.
"Transcriptional Regulation of the Interferon Alpha-Inducible Protein-27 Like 2b by the Peroxisome Proliferator-Activated Receptor γ in Fatty Liver Disease"
doi.org/10.1111/gtc....
Author's Comment ➡️
Transcriptional Regulation of the Interferon Alpha‐Inducible Protein‐27 Like 2b by the Peroxisome Proliferator‐Activated Receptor γ in Fatty Liver Disease
PPARγ directly regulates the interferon-inducible Ifi27l2b gene through a PPRE in the fatty liver. Its expression is elevated in obese and alcohol-fed mice, enhanced by PPARγ ligands, and suppressed ...
doi.org
October 10, 2025 at 1:49 AM
Genes to Cells
Volume 30, Issue 5, 2025.
"Transcriptional Regulation of the Interferon Alpha-Inducible Protein-27 Like 2b by the Peroxisome Proliferator-Activated Receptor γ in Fatty Liver Disease"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 5, 2025.
"Transcriptional Regulation of the Interferon Alpha-Inducible Protein-27 Like 2b by the Peroxisome Proliferator-Activated Receptor γ in Fatty Liver Disease"
doi.org/10.1111/gtc....
Author's Comment ➡️
Genes to Cells
Volume 30, Issue 5, 2025.
"Staphylococcal γ-Hemolysin AB and γ-Hemolysin CB Differentially Activate Murine Bone Marrow-Derived Mast Cells"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 5, 2025.
"Staphylococcal γ-Hemolysin AB and γ-Hemolysin CB Differentially Activate Murine Bone Marrow-Derived Mast Cells"
doi.org/10.1111/gtc....
Author's Comment ➡️
Staphylococcal γ‐Hemolysin AB and γ‐Hemolysin CB Differentially Activate Murine Bone Marrow‐Derived Mast Cells
The staphylococcal γ-hemolysins HlgAB and HlgCB activate mast cells in different ways. HlgAB induces and augments mast cell degranulation in a pore-formation-dependent manner, whereas HlgCB augments ...
doi.org
October 10, 2025 at 1:48 AM
Genes to Cells
Volume 30, Issue 5, 2025.
"Staphylococcal γ-Hemolysin AB and γ-Hemolysin CB Differentially Activate Murine Bone Marrow-Derived Mast Cells"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 5, 2025.
"Staphylococcal γ-Hemolysin AB and γ-Hemolysin CB Differentially Activate Murine Bone Marrow-Derived Mast Cells"
doi.org/10.1111/gtc....
Author's Comment ➡️
Genes to Cells
Volume 30, Issue 5, 2025.
"Loss of Nuclear Protein Dyro Causes Abnormalities in Nurse Cell Nuclei and Abort Oogenesis at Mid-Oogenesis Checkpoint"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 5, 2025.
"Loss of Nuclear Protein Dyro Causes Abnormalities in Nurse Cell Nuclei and Abort Oogenesis at Mid-Oogenesis Checkpoint"
doi.org/10.1111/gtc....
Author's Comment ➡️
Loss of Nuclear Protein Dyro Causes Abnormalities in Nurse Cell Nuclei and Abort Oogenesis at Mid‐Oogenesis Checkpoint
In Dyro mutant ovaries, oogenesis is aborted during Stage 8–9, corresponding to the mid-oogenesis checkpoint. In Dyro mutant nurse cells, the nucleoli were confined to small spaces between thickened ...
doi.org
October 10, 2025 at 1:47 AM
Genes to Cells
Volume 30, Issue 5, 2025.
"Loss of Nuclear Protein Dyro Causes Abnormalities in Nurse Cell Nuclei and Abort Oogenesis at Mid-Oogenesis Checkpoint"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 5, 2025.
"Loss of Nuclear Protein Dyro Causes Abnormalities in Nurse Cell Nuclei and Abort Oogenesis at Mid-Oogenesis Checkpoint"
doi.org/10.1111/gtc....
Author's Comment ➡️
Genes to Cells
Volume 30, Issue 5, 2025.
"Maturation Status of Rat Lung Epithelial Cells in Interspecies Chimeras Generated by Blastocyst Complementation"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 5, 2025.
"Maturation Status of Rat Lung Epithelial Cells in Interspecies Chimeras Generated by Blastocyst Complementation"
doi.org/10.1111/gtc....
Author's Comment ➡️
Maturation Status of Rat Lung Epithelial Cells in Interspecies Chimeras Generated by Blastocyst Complementation
Interspecies chimeras generated by blastocyst complementation using rat ES cells injected into Fgfr2b-knockout mouse embryos—lacking lung epithelium—are gestated by a mouse surrogate and delivered at...
doi.org
October 10, 2025 at 1:46 AM
Genes to Cells
Volume 30, Issue 5, 2025.
"Maturation Status of Rat Lung Epithelial Cells in Interspecies Chimeras Generated by Blastocyst Complementation"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 5, 2025.
"Maturation Status of Rat Lung Epithelial Cells in Interspecies Chimeras Generated by Blastocyst Complementation"
doi.org/10.1111/gtc....
Author's Comment ➡️
Genes to Cells
Volume 30, Issue 5, 2025.
"ERSAtool: A User-Friendly R/Shiny Comprehensive Transcriptomic Analysis Interface Suitable for Education"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 5, 2025.
"ERSAtool: A User-Friendly R/Shiny Comprehensive Transcriptomic Analysis Interface Suitable for Education"
doi.org/10.1111/gtc....
Author's Comment ➡️
ERSAtool: A User‐Friendly R/Shiny Comprehensive Transcriptomic Analysis Interface Suitable for Education
The Educational RNA-Seq Analysis tool (ERSAtool) provides a comprehensive R/Shiny interface with an intuitive graphical visualization of the entire RNA-seq analysis pipeline, enabling users to perfor...
doi.org
October 10, 2025 at 1:44 AM
Genes to Cells
Volume 30, Issue 5, 2025.
"ERSAtool: A User-Friendly R/Shiny Comprehensive Transcriptomic Analysis Interface Suitable for Education"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 5, 2025.
"ERSAtool: A User-Friendly R/Shiny Comprehensive Transcriptomic Analysis Interface Suitable for Education"
doi.org/10.1111/gtc....
Author's Comment ➡️
Genes to Cells
Volume 30, Issue 5, 2025.
"The meeting report on the 5th international conference of the chromosomal SMC complexes"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 5, 2025.
"The meeting report on the 5th international conference of the chromosomal SMC complexes"
doi.org/10.1111/gtc....
Author's Comment ➡️
The Meeting Report on the Fifth International Conference of the Chromosomal SMC Complexes
The fifth international meeting, entitled “SMC Complexes: Orchestrating Diverse Genome Functions,” took place in Numazu, Japan to further our understanding of large-scale chromosome organization and ....
doi.org
October 10, 2025 at 1:41 AM
Genes to Cells
Volume 30, Issue 5, 2025.
"The meeting report on the 5th international conference of the chromosomal SMC complexes"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 5, 2025.
"The meeting report on the 5th international conference of the chromosomal SMC complexes"
doi.org/10.1111/gtc....
Author's Comment ➡️
Genes to Cells
Volume 30, Issue 5, 2025.
"Paralog-Dependent Specialization of Paf1C Subunit, Ctr9, for Sex Chromosome Gene Regulation and Male Germline Differentiation in Drosophila"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 5, 2025.
"Paralog-Dependent Specialization of Paf1C Subunit, Ctr9, for Sex Chromosome Gene Regulation and Male Germline Differentiation in Drosophila"
doi.org/10.1111/gtc....
Author's Comment ➡️
Paralog‐Dependent Specialization of Paf1C Subunit, Ctr9, for Sex Chromosome Gene Regulation and Male Germline Differentiation in Drosophila
We show that Drosophila melanogaster genome maintains testis-specific paralogs encoding components of the transcription regulator Paf1C. One of the paralog products, Ctr9t, forms a unique compartment....
doi.org
October 10, 2025 at 1:39 AM
Genes to Cells
Volume 30, Issue 5, 2025.
"Paralog-Dependent Specialization of Paf1C Subunit, Ctr9, for Sex Chromosome Gene Regulation and Male Germline Differentiation in Drosophila"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 5, 2025.
"Paralog-Dependent Specialization of Paf1C Subunit, Ctr9, for Sex Chromosome Gene Regulation and Male Germline Differentiation in Drosophila"
doi.org/10.1111/gtc....
Author's Comment ➡️
【NEWS】 Professor / Division of Biological Science, Graduate School of Science, Nagoya University
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September 8, 2025 at 8:22 AM
【NEWS】 Professor / Division of Biological Science, Graduate School of Science, Nagoya University
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【NEWS】 Announcement of an assistant professor position （Department of Histology and Cell Biology, Faculty of Medicine, Kanazawa University, Japan） www.mbsj.jp/en/ads/recru...
September 3, 2025 at 7:02 AM
【NEWS】 Announcement of an assistant professor position （Department of Histology and Cell Biology, Faculty of Medicine, Kanazawa University, Japan） www.mbsj.jp/en/ads/recru...
【NEWS】 【Last Call! Registration for GloBIAS2025 is extended】Registration for GloBIAS Bioimage Analysis Conference 2025 is open
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August 29, 2025 at 8:20 AM
【NEWS】 【Last Call! Registration for GloBIAS2025 is extended】Registration for GloBIAS Bioimage Analysis Conference 2025 is open
www.mbsj.jp/en/ads/meeti...
www.mbsj.jp/en/ads/meeti...
[📢] #MBSJ2025 Late-breaking Abstracts Submission Period:
📅 Sep 1 (Mon) - 30 (Tue) 2025, JST 17:00
👉Submission Details:
www.aeplan.jp/mbsj2025/en-...
📅 Sep 1 (Mon) - 30 (Tue) 2025, JST 17:00
👉Submission Details:
www.aeplan.jp/mbsj2025/en-...
August 29, 2025 at 5:25 AM
[📢] #MBSJ2025 Late-breaking Abstracts Submission Period:
📅 Sep 1 (Mon) - 30 (Tue) 2025, JST 17:00
👉Submission Details:
www.aeplan.jp/mbsj2025/en-...
📅 Sep 1 (Mon) - 30 (Tue) 2025, JST 17:00
👉Submission Details:
www.aeplan.jp/mbsj2025/en-...
【NEWS】Team Director: Laboratory for Intracellular Dynamic Structure of Molecules (tentative) and NMR Operation Team, Advanced Multi-Omics Technology Division, RIKEN Center for Integrative Medical Sciences
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August 25, 2025 at 12:49 AM
【NEWS】Team Director: Laboratory for Intracellular Dynamic Structure of Molecules (tentative) and NMR Operation Team, Advanced Multi-Omics Technology Division, RIKEN Center for Integrative Medical Sciences
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【NEWS】Staff Position Openings: Faculty Position in the Graduate School of Science, The University of Osaka/Professor
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August 21, 2025 at 1:21 AM
【NEWS】Staff Position Openings: Faculty Position in the Graduate School of Science, The University of Osaka/Professor
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【MBSJ Topics】 Pre-Event Survey for The Career Development Committee Lunchtime Seminar 2025
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docs.google.com/forms/d/e/1F...
Pre-Event Survey for The Career Development Committee Lunchtime Seminar 2025
At the 48th Annual Meeting of the Molecular Biology Society of Japan (MBSJ2025), we will host two lunchtime seminars titled “A Researcher’s Life without Worrying about Livelihood” and “Strategies Chan...
docs.google.com
August 8, 2025 at 7:39 AM
【MBSJ Topics】 Pre-Event Survey for The Career Development Committee Lunchtime Seminar 2025
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Genes to Cells
Volume 30, Issue 4, 2025.
"Meeting Report on the 1st Asia & Pacific Bioinformatics Joint Conference (APBJC 2024)"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 4, 2025.
"Meeting Report on the 1st Asia & Pacific Bioinformatics Joint Conference (APBJC 2024)"
doi.org/10.1111/gtc....
Author's Comment ➡️
August 6, 2025 at 9:31 AM
Genes to Cells
Volume 30, Issue 4, 2025.
"Meeting Report on the 1st Asia & Pacific Bioinformatics Joint Conference (APBJC 2024)"
doi.org/10.1111/gtc....
Author's Comment ➡️
Volume 30, Issue 4, 2025.
"Meeting Report on the 1st Asia & Pacific Bioinformatics Joint Conference (APBJC 2024)"
doi.org/10.1111/gtc....
Author's Comment ➡️