Michael Weissman
@mbweissman.bsky.social
91 followers 120 following 240 posts
physicist, does some stats etc. https://scholar.google.com/citations?user=FHa6WX4AAAAJ&hl=en https://michaelweissman.substack.com/ https://www.dailykos.com/users/docmidwest https://x.com/mbw61567742
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A slightly revised version is now up.
The corrections to the Pekar 2022 Science paper claiming multiple SARS-CoV-2 introductions are factorizable and simple, using data contained in the paper and minimal assumptions. Their data and model imply that a single introduction was more likely.
arxiv.org/abs/2510.01484
Bayesian Re-Analysis of the Phylogenetic Topology of Early SARS-CoV-2 Case Sequences
A much-cited 2022 paper by Pekar et al. claimed that Bayesian analysis of the molecular phylogeny of early SARS-CoV-2 cases indicated that it was more likely that two successful introductions to human...
arxiv.org
Those differences are not all "rewards", i.e. causal effects. Economists these days are supposed to be more into finding methods of doing causal inference. (This is aside from the issue of allowing for costs in time and $.)
The genome level. That's all part of standard evolutionary models. It's part of why incremental additive fitness gets selected for more readily than incremental fitness from interactions- the latter can get lost pretty quickly, especially if the interactions are between distant genes.
Genomes are pretty stable. The basic rules of evolution by differential reproductive rates do not depend on semantics.
As you say, RFK is a liar (and a lunatic). Just saying so will not convince people who sort of like him. Why believe us rather than him? A mixed strategy including careful factual work makes sense. Science can be better than competing authoritarian cults.
My guess would be a small mammal that eats low-calorie foods, due to surface/volume scaling setting metabolic rates.
With troops being employed for domestic suppression and war looming, I briefly escaped into nostalgic family memories.
michaelweissman.substack.com/p/more-stori...
More stories from my dad
focus on Los Alamos.
michaelweissman.substack.com
This sounds like a useful advance. Major advances (nasal vax, t-cell stimulating vax targeting conserved epitopes,..) are going to be slowed by Trump's attacks on public health.
This is urgent. We have until noon Sat. to get 10 k alumni signers for this amicus brief. Harvard may suck, but this is where the front lines are in the defense against Trump's attacks on science and education. Please sign if you're eligible. and circulate!
docs.google.com/forms/d/e/1F...
Harvard Alumni Amicus Brief Sign On
This is the sign-on form for an amicus curiae ("friend of the court") brief from Harvard alumni. The brief will be filed in support of Harvard, in its lawsuit challenging the U.S. government's unlawf...
docs.google.com
There was more interest than I expected in this niche substack answering Scott Alexander on Covid origins. It may be more generally useful for its brief discussion of how hierarchical Bayes is needed in messy practical problems.
michaelweissman.substack.com/p/open-lette...
Open Letter to Scott Alexander
It's ok to change your mind
michaelweissman.substack.com
The other side is indeed overt fascism, which is why it's necessary to tack to win support. Probably left on some economic issues and right on some social issues. The econ-right, social-left quadrant is almost unpopulated except for big donors.
Why does it matter now? Partly to avoid dragging credibility down on the public health issues by tying it to the weak zoo story. I try to explain here.
michaelweissman.substack.com/p/open-lette...
Open Letter to Scott Alexander
It's ok to change your mind
michaelweissman.substack.com
Your criticisms of Immerwahr on the response to Covid mostly look on target. Unfortunately, he's closer to being right on the origin question. There's a reason groups like the French Academy of Medicine are now leaning toward lab leak. michaelweissman.substack.com/p/an-inconve...
An Inconvenient Probability v5.11
Bayesian analysis of the probable origins of Covid. Quantifying "friggin' likely"
michaelweissman.substack.com
Reposted by Michael Weissman
carlbergstrom.com
tl;dr — this EO co-opts the language of open science to implement a system of political control wherein presidential appointees are given broad latitude to designate any number of reasonable scientific activities and inferences as scientific misconduct, and to penalize those involved accordingly.
Restoring Gold Standard Science
By the authority vested in me as President by the Constitution and the laws of the United States of America, including section 7301 of title 5, United
www.whitehouse.gov
All the analyses say that B is not ancestral, which is the fact used in my HSM side calculation. I discuss 1 vs 2 spills not for a BF but to illustrate the shocking illogic of a prominent paper, P2022.
Rare events happen but they're rare. So that goes into the probabilities.
No. That's not how conditional probabilities under competing hypotheses work.
Sure. But the incorrect way you wrote it indicates that you haven't bothered to start to think about the method. No one who had read even the briefest intro would write about negative BFs.
Reposted by Michael Weissman
carlbergstrom.com
Harvard today, your institution tomorrow.

It's all part of the Project 2025 plan to destroy high education in America.

All leading US universities depend on federal funding and tuition dollars from international students. They severely curtailed the former. Now they're eliminating the latter.
The Trump administration on Thursday halted Harvard University’s ability to enroll international students, taking aim at a crucial funding source for the nation’s oldest and wealthiest college in a major escalation in the administration’s efforts to pressure the elite school to fall in line with the president’s agenda.
There is no such thing as a negative BF. If their BF was 0.0 then they would have been 100% sure that it was not a lab leak. Math isn't just another form of free association.