Jason McLellan
@mclellanlab.bsky.social
3.6K followers 200 following 470 posts
Structural virology / Structure-based vaccine design mclellanlab.org Professor of Molecular Biosciences The University of Texas at Austin Opinions are my own and not the views of my employer
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mclellanlab.bsky.social
Thanks Marija! Drinks on me in Freiburg!
mclellanlab.bsky.social
Thanks Alex! The work we do really is soo collaborative.
mclellanlab.bsky.social
I'm honored to receive a MacArthur Fellowship. As always, I extend my sincerest thanks to all my wonderful mentors, colleagues, collaborators, admins, and trainees who make this work possible. #MacFellow
texasscience.bsky.social
UT Austin has a new “genius grant” recipient!

Texas Science professor Jason McLellan has been awarded a MacArthur Fellowship — aka the “genius grant” — by The MacArthur Foundation.

#TexasScience @mclellanlab.bsky.social #MacArthurGenius @utaustin.bsky.social
cns.utexas.edu/news/accolad...
Virus Slayer Awarded ‘Genius Grant’ by MacArthur Foundation
The award recognizes Jason McLellan’s work to investigate how viruses infect our cells and to develop new treatments for infectious disease.
cns.utexas.edu
mclellanlab.bsky.social
Wow, congratulations Jamie!!
mclellanlab.bsky.social
In addition, 7/8 antibodies targeting MPXV cross-reacted with VARV (smallpox) OPG153. We mapped 3 epitopes on OPG153 by cryo-EM and showed that immunization with the globular domain of OPG153 can elicit significantly higher nAb titers than MVA-BN against VACV and MPXV. doi.org/10.1101/2025....
mclellanlab.bsky.social
Our preprint, in collaboration with Rino Rappuoli & Emanuele Andreano, is out! Co-led by colleagues at TLS, my grad student Ling Zhou @lingzhou.bsky.social, and postdoc Emily Rundlet @cryoemily.bsky.social, we identified OPG153 as a poxvirus bnAb target via B cell isolation & AlphaFold3 prediction.