Michael Anderson
@md-dew.bsky.social
Microscopist and staff scientist. Into automation, electronic design, all things microscopes and electrophysiology. Currently in abusive relationship with the Miami Dolphins.
Sorry, I mean his chosen Qb. I can see Mike being a good hc for a different franchise to target and give him that second chance.
January 4, 2026 at 5:16 PM
Sorry, I mean his chosen Qb. I can see Mike being a good hc for a different franchise to target and give him that second chance.
IMO Tua was good chosen Qb. I get he fell apart at an unprecedented rate which is why I'm more willing to give Mike a pass. With the said, while I like Mike and think he deserves more chances, I don't believe enough in him to compromise doing a full reset in order to give him that next chance.
January 4, 2026 at 5:15 PM
IMO Tua was good chosen Qb. I get he fell apart at an unprecedented rate which is why I'm more willing to give Mike a pass. With the said, while I like Mike and think he deserves more chances, I don't believe enough in him to compromise doing a full reset in order to give him that next chance.
This was helpful. I am asking because I am working on a project related to what you published and knew you would have helpful info. I do work with oxidative bleaching BTW. I actually suspect it's bubble formation that disrupts tissue and not oxidation itself.
January 3, 2026 at 5:30 AM
This was helpful. I am asking because I am working on a project related to what you published and knew you would have helpful info. I do work with oxidative bleaching BTW. I actually suspect it's bubble formation that disrupts tissue and not oxidation itself.
I work with a bubble free oxidative agent and have published FFPE duodenal tissue having no detectable tissue loss after 40 cycles. In unpublished work I have seen 0.5um slices from a PF fixed cell spheroid with no support matrix, have no detectable loss after 10 cycles.
January 3, 2026 at 5:28 AM
I work with a bubble free oxidative agent and have published FFPE duodenal tissue having no detectable tissue loss after 40 cycles. In unpublished work I have seen 0.5um slices from a PF fixed cell spheroid with no support matrix, have no detectable loss after 10 cycles.
@kevin-dean.bsky.social thank you for the answer. Just to clarify, did you ever experimentally try it or did you hypothesize it won't be as robust and had success with the other method and never tried it?
January 3, 2026 at 1:02 AM
@kevin-dean.bsky.social thank you for the answer. Just to clarify, did you ever experimentally try it or did you hypothesize it won't be as robust and had success with the other method and never tried it?
Just read the paper and I'm impressed! I am curious though. You mentioned techniques like CyCIF and then used antibody stripping. Why is that? Did you ever try CYCIF?
January 2, 2026 at 9:11 PM
Just read the paper and I'm impressed! I am curious though. You mentioned techniques like CyCIF and then used antibody stripping. Why is that? Did you ever try CYCIF?
This looks great! Such an underappreciated, but important topic. I am going to read it right now.
December 15, 2025 at 6:48 PM
This looks great! Such an underappreciated, but important topic. I am going to read it right now.
Perfect response. I just gdpted a question yesterday and I know the answer to it because I just published the paper on it and even though the paper exists online, it still omitted it. The internet embolden the stupid and unfortunately AI is doubling down on that.
July 17, 2025 at 9:38 AM
Perfect response. I just gdpted a question yesterday and I know the answer to it because I just published the paper on it and even though the paper exists online, it still omitted it. The internet embolden the stupid and unfortunately AI is doubling down on that.
My institution gave us all unlimited gdrives for long term storage so I have been uploading a ton of multiplex data sets and it's possible that it's unlimited size, but I hit an item count limit. So now I have about 2 months of work to take them off, make them until tar folders and re-upload. Fun!
July 8, 2025 at 10:12 AM
My institution gave us all unlimited gdrives for long term storage so I have been uploading a ton of multiplex data sets and it's possible that it's unlimited size, but I hit an item count limit. So now I have about 2 months of work to take them off, make them until tar folders and re-upload. Fun!
That's true! The size has changed, but the struggle to store it has remained constant.
July 7, 2025 at 10:05 PM
That's true! The size has changed, but the struggle to store it has remained constant.
At this point, this is what Texas wants. It's Texas so I'm pretty sure they have more than enough boot straps laying around to pull themselves up by.
July 5, 2025 at 5:05 PM
At this point, this is what Texas wants. It's Texas so I'm pretty sure they have more than enough boot straps laying around to pull themselves up by.
Woah, we got that sweet 200 extra dollars in cold tax credit. That's a government that really values baby making and not just saying it does. I for one am planning on buying a single package of diapers with it, lol.
July 5, 2025 at 4:46 PM
Woah, we got that sweet 200 extra dollars in cold tax credit. That's a government that really values baby making and not just saying it does. I for one am planning on buying a single package of diapers with it, lol.
You have the best taste in movies. The fear street prom one was a good recommendation and I'm pumped about this one too. Love the troma stuff.
June 21, 2025 at 3:07 AM
You have the best taste in movies. The fear street prom one was a good recommendation and I'm pumped about this one too. Love the troma stuff.
If this had merit to it, Elon would be furious that liberal view points arent prevelant enough on Twitter. Just like Elon, you also dont actually care about equal representation and just want conservative talking points to dominate everything and in this moment it's convienent to use representation
June 10, 2025 at 1:55 PM
If this had merit to it, Elon would be furious that liberal view points arent prevelant enough on Twitter. Just like Elon, you also dont actually care about equal representation and just want conservative talking points to dominate everything and in this moment it's convienent to use representation
I am totally going to watch this over the weekend! I didn't realize a new fear street was out.
June 6, 2025 at 5:54 PM
I am totally going to watch this over the weekend! I didn't realize a new fear street was out.
Maybe we need to start presenting the exact ante idea with different terms. It's possible they have a list of nono words and phrases and simply avoiding those is good. It's stupid, but maybe. Maga in general are very sensitive to words and get triggered very easily.
May 31, 2025 at 12:56 PM
Maybe we need to start presenting the exact ante idea with different terms. It's possible they have a list of nono words and phrases and simply avoiding those is good. It's stupid, but maybe. Maga in general are very sensitive to words and get triggered very easily.
No problem. I appreciate that they made a Matlab executable for it. I want it in python though, so I just cloned the repository and I'm working on converting it into python right now. After that, I'll compare results to my approximated method.
May 29, 2025 at 2:45 PM
No problem. I appreciate that they made a Matlab executable for it. I want it in python though, so I just cloned the repository and I'm working on converting it into python right now. After that, I'll compare results to my approximated method.
Fantastic that it's out! I saw the preprint last year and loved the idea behind it. I wasnt able to use the code from it as they were waiting until the nature method paper of its was published, so I made a nice approximation method for it and I've been very impressed. Def the way to go for dehazing.
May 29, 2025 at 1:31 PM
Fantastic that it's out! I saw the preprint last year and loved the idea behind it. I wasnt able to use the code from it as they were waiting until the nature method paper of its was published, so I made a nice approximation method for it and I've been very impressed. Def the way to go for dehazing.
I'm thinking she fully knows what it is. What she did was just a display of loyalty.
May 21, 2025 at 10:41 AM
I'm thinking she fully knows what it is. What she did was just a display of loyalty.
Yup. People are too sensitive and freedom of speech is absolute when it benefits them. Snowflake level freak outs about speech when it doesn't. It's almost like no real principles exist and it's just them co-opting whatever can further their agenda.
May 17, 2025 at 3:47 PM
Yup. People are too sensitive and freedom of speech is absolute when it benefits them. Snowflake level freak outs about speech when it doesn't. It's almost like no real principles exist and it's just them co-opting whatever can further their agenda.
Here is the link article: www.nature.com/articles/s42...
SPECTREPlex: an automated, fast, high-resolution enabled approach for multiplexed cyclic imaging and tissue spatial analysis - Communications Biology
A fast, automated, high-resolution, low-cost multiplex immunofluorescence method to understand spatial organization of tissue.
www.nature.com
April 24, 2025 at 8:19 PM
Here is the link article: www.nature.com/articles/s42...
I don't remember people ever calling for Pat to be canceled. I'd believe it if Pat said that he has said 1000 statements where he prefaced them by saying this is going to get me canceled.
April 12, 2025 at 11:54 PM
I don't remember people ever calling for Pat to be canceled. I'd believe it if Pat said that he has said 1000 statements where he prefaced them by saying this is going to get me canceled.
I think it's because Grier drafted him. Fans assume he can't draft and that he is especially bad at picking olinemen. Grier drafted Paul, thus Paul is a bum. This is just a guess though.
April 7, 2025 at 8:07 PM
I think it's because Grier drafted him. Fans assume he can't draft and that he is especially bad at picking olinemen. Grier drafted Paul, thus Paul is a bum. This is just a guess though.
This makes total sense. I would 100% love it if the nfl did this.
March 19, 2025 at 10:07 PM
This makes total sense. I would 100% love it if the nfl did this.