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Melike Dönertaş @mdonertas.bsky.social · 2d

(4/4) Late registration + poster submissions remain open until we hit capacity.

👉 Register: amc25.leibniz-fli.de/registration/
👉 Full program: amc25.leibniz-fli.de/speakers-pro...

#Microbiome #Aging #Ageing #SystemsBiology #Metagenomics #Neuroscience #AMC2025 #Jena

Registration – AMC2025

amc25.leibniz-fli.de

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Melike Dönertaş @mdonertas.bsky.social · 2d

(3/4) 🤝 Networking & “Meet the Speaker” sessions
🔭 “Voyager” dome show at the Zeiss-Planetarium Jena
🍴 Conference dinner with integrated networking
🥇 Awards for best poster, talk, and “top connector”
💼 Sponsor interactions + sponsor bingo
👇

Registration – AMC2025

amc25.leibniz-fli.de

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Melike Dönertaş @mdonertas.bsky.social · 2d

(2/4) 🗣️ Keynotes: Karine Clément, Niranjan Nagarajan (online), Gianni Panagiotou
🗣️ Invited talks: Eran Blacher, Reena Debray, Daniel Erny, Christoph Kaleta, Yvonne Nolan, Veronica Witte, Bahtiyar Yilmaz
🗣️ Fantastic selected talks from abstracts
📊 Interactive poster sessions

👇

Registration – AMC2025

amc25.leibniz-fli.de

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Melike Dönertaş @mdonertas.bsky.social · 2d

#AMC2025 is almost here (Oct 28–29, Jena) and we’ve opened a few more seats! If you work on host-microbiome interactions, aging, or age-related diseases, bring a poster and join this amazing crowd!

amc25.leibniz-fli.de/registration/

✨ Highlights 👇 🧵 (1/4)

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Melike Dönertaş @mdonertas.bsky.social · Jul 19

Come find us if you are interested in applications of computational biology and statistical methods on #aging and #microbiome research!

Looking forward! #ISMBECCB2025 (3/3)

Melike Dönertaş @mdonertas.bsky.social · Jul 19

I will then participate in the ISCBSC Symposium, joining a panel discussion on multi-omics, organised by the amazing student group of ISCB.

Tayyaba Alvi and Mark Olenik will be presenting their posters in the Microbiome and Machine Learning COSI tracks. #ISMBECCB2025 (2/3)

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Melike Dönertaş @mdonertas.bsky.social · Jul 19

We are in Liverpool for the #ISMBECCB2025!

Tayyaba Alvi, Mark Olenik and I will be delivering a tutorial on Mendelian Randomization on the first day of the conference. (1/3)

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Reposted by Melike Dönertaş

Dilek Koptekin @dilekopter.bsky.social · Jun 26

Happy to share our new study from my PhD on the spread of farming across Anatolia and into the Aegean and then into Europe. @compevohumang.bsky.social

www.science.org/doi/10.1126/...

👇🏽

Out-of-Anatolia: Cultural and genetic interactions during the Neolithic expansion in the Aegean

West Anatolia has been a crucial yet elusive element in the Neolithic expansion from the Fertile Crescent to Europe. In this work, we describe the changing genetic and cultural landscapes of early Hol...

www.science.org

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Reposted by Melike Dönertaş

Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut @leibnizfli.bsky.social · Jun 23

📢 REMINDER ‼️ AMC - Abstract submission deadline: June 30, 2025

The Aging and Microbiome Conference 2025 #AMC2025 will take place from October 28-29, 2025 in #Jena. Join us for the latest developments and exciting discussions on #microbiome & #aging.

📅 amc25.leibniz-fli.de/registration/

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Reposted by Melike Dönertaş

Melike Dönertaş @mdonertas.bsky.social · Jun 16

📢 Update! The abstract submission deadline for the #AMC2025 Aging and Microbiome Conference has been extended to June 30, 2025!

🔗 amc25.leibniz-fli.de
📌 Jena, Germany
📆 Oct 28-29, 2025

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Melike Dönertaş @mdonertas.bsky.social · Jun 17

I'm attending #ISMBECCB2025 in Liverpool, United Kingdom from July 20-24. Who else is going? Register here and don't miss it! invt.io/1bxb8kd9bqu

I'm participating the ISMB/ECCB 2025 conference, join me!

Register now

invt.io

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Melike Dönertaş @mdonertas.bsky.social · Jun 16

📢 Update! The abstract submission deadline for the #AMC2025 Aging and Microbiome Conference has been extended to June 30, 2025!

🔗 amc25.leibniz-fli.de
📌 Jena, Germany
📆 Oct 28-29, 2025

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Melike Dönertaş @mdonertas.bsky.social · Jun 7

A blood-based epigenetic clock for intrinsic capacity predicts mortality and is associated with clinical, immunological and lifestyle factors - Nature Aging www.nature.com/articles/s43...

A blood-based epigenetic clock for intrinsic capacity predicts mortality and is associated with clinical, immunological and lifestyle factors - Nature Aging

Fuentealba and colleagues build and validate a DNA methylation clock of intrinsic capacity (IC) to bridge resource-intensive clinical assessments of IC with molecular readouts of aging, highlighting…

www.nature.com

Melike Dönertaş @mdonertas.bsky.social · May 29

Abstract submission deadline in two days!!

Melike Dönertaş @mdonertas.bsky.social · May 19

🚨 Aging and Microbiome Conference 2025
📌 Jena, Germany
📆 October 28-29, 2025
⏰ Abstract submission deadline: 31.05.2025
ℹ️ amc25.leibniz-fli.de

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Melike Dönertaş @mdonertas.bsky.social · May 26

Read the full study here: biorxiv.org/content/10.1...

We'd love feedback- especially from folks working on microbiomes, host aging, or evolutionary ecology! DMs open, feedback welcome!

Age-dependent gut microbiota dynamics and their association with male fitness traits in Drosophila melanogaster

Growing evidence suggests that the gut microbiota plays a key role in shaping life history in a wide range of species, including well-studied model organisms like Drosophila melanogaster. Although rec...

biorxiv.org

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Melike Dönertaş @mdonertas.bsky.social · May 26

Interestingly, Acetobacter sp. have been linked to positive effects on female reproduction. We find that in males, certain Acetobacter taxa are associated with reduced lifespan and accelerated aging, suggesting potential sex-specific or antagonistic roles.

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Melike Dönertaş @mdonertas.bsky.social · May 26

While microbiota diversity changed with age, we found no strong link between diversity and male fitness. But specific taxa, especially Acetobacter, were consistently associated with aging-related traits.

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Melike Dönertaş @mdonertas.bsky.social · May 26

4️⃣ Early-life rel. abd. of A. indonesiensis ~ reproductive senescence
5️⃣ Microbiota composition predicts chronological age (>85% accuracy) but not life history traits (possibly due to design/sample size)

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Melike Dönertaş @mdonertas.bsky.social · May 26

Main findings:
1️⃣ Age-related shifts in the relative abundance of Acetobacter, Ralstonia, and Leuconostoc
2️⃣ Late-life rel. abundance of A. ascendens & A. pasteurianus ~ shorter lifespan
3️⃣ Early-life rel. abd. of A. ascendens ~ faster functional decline

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Melike Dönertaş @mdonertas.bsky.social · May 26

Using 22 DGRP lines, we measured:
- Lifespan
- Early/late reproduction
- Early/late climbing performance
- Gut microbiota (16S rRNA) at days 5 & 26

We then asked: How does microbiota composition change with age and how does this relate to male life-history?

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Melike Dönertaş @mdonertas.bsky.social · May 26

Super happy to share our new preprint with Zahida Sultanova and an amazing team! We explored how age-related changes in gut microbiota associate with life history traits - lifespan, reproduction, and performance - in male Drosophila melanogaster.

www.biorxiv.org/content/10.1...

Age-dependent gut microbiota dynamics and their association with male fitness traits in Drosophila melanogaster

Growing evidence suggests that the gut microbiota plays a key role in shaping life history in a wide range of species, including well-studied model organisms like Drosophila melanogaster. Although rec...

www.biorxiv.org

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Reposted by Melike Dönertaş

Melike Dönertaş @mdonertas.bsky.social · May 19

🚨 Aging and Microbiome Conference 2025
📌 Jena, Germany
📆 October 28-29, 2025
⏰ Abstract submission deadline: 31.05.2025
ℹ️ amc25.leibniz-fli.de

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Melike Dönertaş @mdonertas.bsky.social · May 20

First evidence of possible language-like communication in dolphins phys.org/news/2025-05...

First evidence of possible language-like communication in dolphins

Researchers at the Woods Hole Oceanographic Institution (WHOI) and partner institutions, including the Brookfield Zoo Chicago's Sarasota Dolphin Research Program (SDRP), are the winners of the…

phys.org

Melike Dönertaş @mdonertas.bsky.social · May 19

🚨 Aging and Microbiome Conference 2025
📌 Jena, Germany
📆 October 28-29, 2025
⏰ Abstract submission deadline: 31.05.2025
ℹ️ amc25.leibniz-fli.de

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Melike Dönertaş @mdonertas.bsky.social · May 14

Embryonic macrophages orchestrate niche cell homeostasis for the establishment of the definitive hematopoietic stem cell pool - Nature Communications www.nature.com/articles/s41...

Embryonic macrophages orchestrate niche cell homeostasis for the establishment of the definitive hematopoietic stem cell pool - Nature Communications

Haematopoietic stem cells (HSC) are responsible for blood cell generation and reside in the bone marrow. Here, the authors show that macrophages in the bone marrow originate from embryonic or adult…

www.nature.com

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