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Stay up-to-date on the latest medical news by following our team of experienced, award-winning reporters. #MedSky go.bsky.app/289BbiL
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A dexamethasone-sparing regimen involving lenalidomide (Revlimid) and the anti-CD38 drug daratumumab (Darzalex) was safe and effective in older, frail patients with newly diagnosed multiple myeloma, according to a randomized trial.
https://www.medpagetoday.com/hematologyoncology/myeloma/117821
Some Frail Myeloma Patients Can Quickly Wean Off Dexamethasone, Study Says
Dose reduction combined with daratumumab-lenalidomide improved oncologic outcomes
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medpagetoday.com
Regulation of intravenous (IV) hydration spas varies widely across the U.S., with only four states listing policies that address all four key areas of oversight, according to a mixed-methods study.

Read more at: https://www.medpagetoday.com/publichealthpolicy/healthpolicy/117824?trw=no
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A new treatment algorithm from the European Association for the Study of Obesity (EASO) recommends opting for semaglutide (Wegovy) or tirzepatide (Zepbound) first when "substantial" weight loss is needed in a patient.

Read more at: https://www.medpagetoday.com/primarycare/obesity/117800?trw=no
Pick GLP-1s as First Drug Option in Obesity, Guidelines From Abroad Say
But treatment should be tailored to a patient's comorbidities and preferences
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Physician attrition increased across the board from 2013 to 2019, but some physician and patient characteristics were linked to higher rates, a longitudinal study found.

Read more at: https://www.medpagetoday.com/publichealthpolicy/workforce/117818?trw=no
These Physicians Are More Likely to Leave Clinical Practice
Attrition rates rose over several years, and were worse for some groups
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William Schaffner, MD, also of Vanderbilt University, further noted that "the combined vaccine works brilliantly -- why change what works?"
medpagetoday.com
"How do we have an acting director of the CDC with no scientific credentials who is making these recommendations?" said Kathryn Edwards, MD, of Vanderbilt University Medical Center.
medpagetoday.com
"This is yet another example of efforts to create distrust and sow doubt, and the tragic consequence will be children who lose the opportunity to develop protection against these diseases," said Susan J. Kressly, MD, president of @ameracadpeds.bsky.social.
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"I call on vaccine manufacturers to develop safe monovalent vaccines to replace the combined MMR," Acting CDC Director Jim O'Neill said Monday on X.

This drew swift rebukes from pediatric and infectious disease experts⬇️
medpagetoday.com
Providing pediatricians with education tools and prompts substantially increased how often they recommended early peanut introduction for infants, in line with peanut allergy guidelines, the randomized iREACH trial showed.
https://www.medpagetoday.com/allergyimmunology/allergy/117814
Clinician Tools, Prompts Boosted Early Peanut Introduction
Randomized trial shows big advantage, especially for the simpler low-risk infant recommendations
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medpagetoday.com
School districts and private schools with low measles, mumps, and rubella coverage are often located in counties with rates at or near the 95% target for herd immunity, according to a statewide analysis of Texas counties.

https://www.medpagetoday.com/infectiousdisease/infectioncontrol/117826?trw=no
To Prevent Measles Outbreaks, Look at Schools' Vaccine Rates, Study Suggests
State- and county-level MMR vaccination rates may obscure the riskiest potential hot spots
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"Can the agency as we know it survive?"

Read the #OpEd from MedPage Today Editor-in-Chief @jeremyfaust.bsky.social on where the CDC stands amid recent changes:

https://www.medpagetoday.com/opinion/faustfiles/117811?trw=no
Opinion | There Are Now Two CDCs
Can the agency survive?
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medpagetoday.com
The FDA granted marketing authorization for the ProSense Cryoablation System for small, early-stage breast cancer in older women not suitable for surgery, maker IceCure announced.
https://www.medpagetoday.com/hematologyoncology/breastcancer/117812
FDA Says Yes to Cryoablation for Early Breast Cancer
ProSense is indicated for women 70 and older not suitable for surgery
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medpagetoday.com
Children with acute UA treated with antibiotics alone faced significantly higher risks of treatment failure & serious complications within a year compared with those who underwent appendectomy, according to a meta-analysis.
https://www.medpagetoday.com/gastroenterology/generalgastroenterology/117801
Study Questions Antibiotic Use for Kids' Appendicitis
Data will help clinicians and family with shared-decision making for optimal care, expert says
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medpagetoday.com
For children who have never been vaccinated against the flu, getting two doses of the inactivated flu vaccine was associated with improved protection compared with getting one dose, but only in those younger than 3 years.
https://www.medpagetoday.com/infectiousdisease/uritheflu/117783
Starting Toddlers With Two Doses of the Flu Shot Boosted Effectiveness
But this benefit was only significant in a certain age group
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medpagetoday.com
Huntr/x might be going 🎵 up, up, up 🎵 in the song "Golden" from Netflix's "KPop Demon Hunters"... but so too may the number of pediatric burn cases, thanks to a social media trend inspired by a scene from the film.

Read more at: https://www.medpagetoday.com/popmedicine/cultureclinic/117790?trw=no
'KPop Demon Hunters' Ramen Noodle Challenge May Put Kids at Risk of Burns
Impressionable kids might not have a sense of the harms hot liquid can inflict
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medpagetoday.com
The CDC endorsed recommendations from the newly installed members of ACIP for "individual-based decision-making" on COVID-19 booster shots and for giving the MMR vaccine and the varicella vaccine to toddlers in two separate shots.
https://www.medpagetoday.com/infectiousdisease/covid19vaccine/117817
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The American Medical Association (AMA) and dozens of other medical specialty societies urged Secretary Kristi Noem to exempt physicians from a recent executive order placing restrictions on the H-1B visa program.

Read more at: https://www.medpagetoday.com/publichealthpolicy/workforce/117796?trw=no
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"Despite overwhelming evidence and broad public support for mifepristone, there have been relentless attempts to restrict access."

Read the #OpEd from Hey Jane CEO and founder Kiki Freedman, MBA, at: https://www.medpagetoday.com/opinion/second-opinions/117786?trw=no
Opinion | Mifepristone Is Under Attack Again – With the Same Old Playbook
Ignore the evidence, stir up doubt, and leave patients to bear the consequences
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medpagetoday.com
Exposure to ambient trichloroethylene -- a common chemical used in degreasing and dry cleaning -- correlated with a higher risk of Parkinson's disease, an analysis of over a million Medicare beneficiaries showed.
https://www.medpagetoday.com/neurology/parkinsonsdisease/117770
Parkinson's Risk Rises With Outdoor Air Chemical Exposure
Despite EPA ban, thousands of sites remain contaminated with trichloroethylene
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medpagetoday.com
Fellow nurses: how can we help rebuild patients' trust in the healthcare system? It's time to share your thoughts ⬇️

Join Katie Boston-Leary, PhD, MBA, MHA, RN, NEA-BC, FADLN, FAONL, of @americannurses.bsky.social, in this week's edition of The Nurses' Station: www.medpagetoday.com/nursing/nurs...
Fellow Nurses: How Can We Help Rebuild Patients' Trust in the Healthcare System?
Join in and discuss this week's topic with your colleagues
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medpagetoday.com
In the first randomized trial of stroke prevention after ischemic stroke in patients who have both nonvalvular Afib and atherosclerosis, adding an antiplatelet to anticoagulant therapy increased bleeding without preventing more ischemic events.
https://www.medpagetoday.com/cardiology/strokes/117805
Anticoagulant Alone Safer in Stroke Patients With Afib and Atherosclerosis
Dual strategy not worth the risk for these patients, trial shows
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medpagetoday.com
Use of an ambient artificial intelligence scribe was associated with a significant reduction in burnout among ambulatory care clinicians, a multicenter quality improvement study suggested.
https://www.medpagetoday.com/practicemanagement/informationtechnology/117791
More Evidence That AI Scribes May Reduce Clinician Burnout
Clinicians also reported more time to fully focus on patients
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