Lynn Megeney/Megeney Lab
megeneyscience.bsky.social
Lynn Megeney/Megeney Lab
@megeneyscience.bsky.social
Grandfather of the Non-lethal roles of cell death proteins (along with Eli Arama); all things caspases/metacaspases, control of physiologic DNA strand breaks and adaptive cardiac remodeling
www.biorxiv.org/content/10.1...

First post on BlueSky, our updated paper on bioRxriv Re: CAD and the origin of break point translocations
Caspase-Activated DNase localizes to cancer causing translocation breakpoints during cell differentiation
Caspase activated DNase (CAD) induced DNA breaks promote cell differentiation and therapy-induced cancer cell resistance. CAD targeting activity is assumed to be unique to each condition, as different...
www.biorxiv.org
January 28, 2025 at 8:36 PM