melanie_blasius.bsky.social
@melacular.bsky.social
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Our new preprint on how ribosome problems activate the ZAK pathway is now available on bioRxiv 🎊
New preprint out!
Our latest work on how ZAKα is activated by stalled or/and collided ribosomes is now online🎉. #Ribosome #RibotoxicStressResponse #ZAKα #Translation #mRNA www.biorxiv.org/content/10.1...
Our latest work on how ZAKα is activated by stalled or/and collided ribosomes is now online🎉. #Ribosome #RibotoxicStressResponse #ZAKα #Translation #mRNA www.biorxiv.org/content/10.1...
ZAKα is a sensor of mRNA stasis at the ribosomal exit channel
Despite a growing interest in the ribotoxic stress response (RSR), it remains unknown how the upstream p38 and JNK-activating MAP3 kinase ZAKα senses translational impairment. Combining Alphafold3 pre...
www.biorxiv.org
December 3, 2025 at 3:15 PM
Our new preprint on how ribosome problems activate the ZAK pathway is now available on bioRxiv 🎊
Reposted by melanie_blasius.bsky.social
Time for our first post here 🥳 Our latest paper is online 🙌
We show that UV activates the ribotoxic stress response, which causes inflammation, cell death and thickening in skin. Read about a role for the RSR separate from DNA damage signaling in response to sunburn: ✨☀️ www.cell.com/molecular-ce...
We show that UV activates the ribotoxic stress response, which causes inflammation, cell death and thickening in skin. Read about a role for the RSR separate from DNA damage signaling in response to sunburn: ✨☀️ www.cell.com/molecular-ce...
The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo
The acute skin reaction to sunburn, encompassing keratinocyte cell death, inflammation,
and epidermal thickening, has traditionally been ascribed to DNA damage responses.
Using a mouse model deficient...
www.cell.com
November 26, 2024 at 10:02 AM
Time for our first post here 🥳 Our latest paper is online 🙌
We show that UV activates the ribotoxic stress response, which causes inflammation, cell death and thickening in skin. Read about a role for the RSR separate from DNA damage signaling in response to sunburn: ✨☀️ www.cell.com/molecular-ce...
We show that UV activates the ribotoxic stress response, which causes inflammation, cell death and thickening in skin. Read about a role for the RSR separate from DNA damage signaling in response to sunburn: ✨☀️ www.cell.com/molecular-ce...
Reposted by melanie_blasius.bsky.social
Wir verlassen X und rufen alle Follower*innen dazu auf, uns bei BlueSky zu folgen. Elon Musk hat den Debatten-Raum Twitter zu einer Hass-Maschine umgebaut, die auch die Bundestagswahl negativ beeinflussen kann. Unsere Erklärung dazu:
#fcsp #tschüssmusk #musk
www.fcstpauli.com/news/der-fc-...
#fcsp #tschüssmusk #musk
www.fcstpauli.com/news/der-fc-...
Wegen Rassismus und Hass-Inhalten: Abschied von X - FC St. Pauli
Debatten-Plattform ist endgültig zur Hass-Maschine geworden ⚽ Verein baut Präsenz auf BlueSky aus ☠ Alle Infos:
www.fcstpauli.com
November 14, 2024 at 9:30 AM
Wir verlassen X und rufen alle Follower*innen dazu auf, uns bei BlueSky zu folgen. Elon Musk hat den Debatten-Raum Twitter zu einer Hass-Maschine umgebaut, die auch die Bundestagswahl negativ beeinflussen kann. Unsere Erklärung dazu:
#fcsp #tschüssmusk #musk
www.fcstpauli.com/news/der-fc-...
#fcsp #tschüssmusk #musk
www.fcstpauli.com/news/der-fc-...