michaeldeghelt.bsky.social
Michael Deghelt
@michaeldeghelt.bsky.social
210 followers 130 following 2 posts
Microbiologist
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Michael Deghelt @michaeldeghelt.bsky.social · Jul 29
#microsky
We challenge the long-standing view that peptidoglycan alone protects cells from bursting.

Our study shows that the periplasm — enclosed by OM–PG connections — acts as a pressure buffer essential for osmoprotection in Gram-negative bacteria.

📄 www.nature.com/articles/s41...
Peptidoglycan–outer membrane attachment generates periplasmic pressure to prevent lysis in Gram-negative bacteria - Nature Microbiology
Outer membrane attachment to peptidoglycan enables periplasmic pressure to build up and counter cytoplasmic turgor pressure, preventing lysis during osmotic challenges in Escherichia coli.
www.nature.com
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michaeldeghelt.bsky.social
Michael Deghelt @michaeldeghelt.bsky.social · Jul 31
Most stories don’t really start the way we write them in papers—and ours is no exception. To find out how it really began with a simple PCR trick, check out our Behind the Paper: « Out Of The Blue, It Came To Me »
👉 communities.springernature.com/posts/out-of...

#MicroSky
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michaeldeghelt.bsky.social
Michael Deghelt @michaeldeghelt.bsky.social · Jul 29
#microsky
We challenge the long-standing view that peptidoglycan alone protects cells from bursting.

Our study shows that the periplasm — enclosed by OM–PG connections — acts as a pressure buffer essential for osmoprotection in Gram-negative bacteria.

📄 www.nature.com/articles/s41...
Peptidoglycan–outer membrane attachment generates periplasmic pressure to prevent lysis in Gram-negative bacteria - Nature Microbiology
Outer membrane attachment to peptidoglycan enables periplasmic pressure to build up and counter cytoplasmic turgor pressure, preventing lysis during osmotic challenges in Escherichia coli.
www.nature.com
2 40 63