Michal Santocki
@michalsantocki.bsky.social
Postdoctoral Researcher at Frič lab, ICRC, St. Anne's University Hospital Brno | Investigating long-term effects of sepsis | Organoids enthusiast | Myeloid cells geek |
#immunology #sepsis #innateimmunity #intravitalmicroscopy #organoids 👨🏻🔬🔬🩸
#immunology #sepsis #innateimmunity #intravitalmicroscopy #organoids 👨🏻🔬🔬🩸
Pinned
NETs persisting in vasculature undergo self-renewal with consequences for subsequent infection: a mouse model study
Key PointsNET protein components adhere to vascular endothelium for 5 to 8 months, whereas DNA is detached within days but circulates for up to a year.In v
tinyurl.com
I’m thrilled to share that the article based on the findings from my doctoral thesis has been published in the Blood journal! @bloodportfolio.bsky.social
Our study reveals the unexpected longevity and self-renewal of NETs within liver blood vessels during sepsis!🕸️🔬
tinyurl.com/mxph8mrr
#sepsis #NETs
Our study reveals the unexpected longevity and self-renewal of NETs within liver blood vessels during sepsis!🕸️🔬
tinyurl.com/mxph8mrr
#sepsis #NETs
Reposted by Michal Santocki
FricLab at @csac-cz.bsky.social 2025 conference
Jan @friclab.bsky.social presented pre @beatsepsis.bsky.social data
@michalsantocki.bsky.social - BMniche remodelling in sepsis,
@zuzanatomasik -EoE project
@pap_joanna postCOV neutrophils
Jan @friclab.bsky.social presented pre @beatsepsis.bsky.social data
@michalsantocki.bsky.social - BMniche remodelling in sepsis,
@zuzanatomasik -EoE project
@pap_joanna postCOV neutrophils
October 10, 2025 at 9:45 PM
FricLab at @csac-cz.bsky.social 2025 conference
Jan @friclab.bsky.social presented pre @beatsepsis.bsky.social data
@michalsantocki.bsky.social - BMniche remodelling in sepsis,
@zuzanatomasik -EoE project
@pap_joanna postCOV neutrophils
Jan @friclab.bsky.social presented pre @beatsepsis.bsky.social data
@michalsantocki.bsky.social - BMniche remodelling in sepsis,
@zuzanatomasik -EoE project
@pap_joanna postCOV neutrophils
Reposted by Michal Santocki
It’s World #Sepsis Day
Sepsis kills 11 million people each year.
Symptoms incl.:
🔸Fever or shivering
🔸Confusion
🔸Shortness of breath
🔸Rash that does not fade when pressed
🔸Extreme discomfort
🔸Sweaty skin
Seek medical care as soon as possible when an infection is not getting better.
Sepsis kills 11 million people each year.
Symptoms incl.:
🔸Fever or shivering
🔸Confusion
🔸Shortness of breath
🔸Rash that does not fade when pressed
🔸Extreme discomfort
🔸Sweaty skin
Seek medical care as soon as possible when an infection is not getting better.
September 13, 2025 at 9:02 AM
It’s World #Sepsis Day
Sepsis kills 11 million people each year.
Symptoms incl.:
🔸Fever or shivering
🔸Confusion
🔸Shortness of breath
🔸Rash that does not fade when pressed
🔸Extreme discomfort
🔸Sweaty skin
Seek medical care as soon as possible when an infection is not getting better.
Sepsis kills 11 million people each year.
Symptoms incl.:
🔸Fever or shivering
🔸Confusion
🔸Shortness of breath
🔸Rash that does not fade when pressed
🔸Extreme discomfort
🔸Sweaty skin
Seek medical care as soon as possible when an infection is not getting better.
Reposted by Michal Santocki
In vivo physiological removal of NETs induces second-wave traps, altering the severity of subsequent infection, depending on its timing. buff.ly/9VmItHw #hemesky #phagocytesgranulocytesandmyelopoiesis
May 5, 2025 at 6:04 PM
In vivo physiological removal of NETs induces second-wave traps, altering the severity of subsequent infection, depending on its timing. buff.ly/9VmItHw #hemesky #phagocytesgranulocytesandmyelopoiesis
I’m thrilled to share that the article based on the findings from my doctoral thesis has been published in the Blood journal! @bloodportfolio.bsky.social
Our study reveals the unexpected longevity and self-renewal of NETs within liver blood vessels during sepsis!🕸️🔬
tinyurl.com/mxph8mrr
#sepsis #NETs
Our study reveals the unexpected longevity and self-renewal of NETs within liver blood vessels during sepsis!🕸️🔬
tinyurl.com/mxph8mrr
#sepsis #NETs
NETs persisting in vasculature undergo self-renewal with consequences for subsequent infection: a mouse model study
Key PointsNET protein components adhere to vascular endothelium for 5 to 8 months, whereas DNA is detached within days but circulates for up to a year.In v
tinyurl.com
May 1, 2025 at 8:05 PM
I’m thrilled to share that the article based on the findings from my doctoral thesis has been published in the Blood journal! @bloodportfolio.bsky.social
Our study reveals the unexpected longevity and self-renewal of NETs within liver blood vessels during sepsis!🕸️🔬
tinyurl.com/mxph8mrr
#sepsis #NETs
Our study reveals the unexpected longevity and self-renewal of NETs within liver blood vessels during sepsis!🕸️🔬
tinyurl.com/mxph8mrr
#sepsis #NETs
Excited to share our new paper🚨📝
We explored SLPI's role in neutrophil migration in psoriasis!
Full paper: link.springer.com/article/10.1...
Big thanks to co-authors! 🙌
#neutrophils #inflammation #psoriasis #SLPI
We explored SLPI's role in neutrophil migration in psoriasis!
Full paper: link.springer.com/article/10.1...
Big thanks to co-authors! 🙌
#neutrophils #inflammation #psoriasis #SLPI
SLPI controls neutrophil migration abilities and impacts neutrophil skin infiltration in experimental psoriasis - Cellular and Molecular Life Sciences
Skin infiltration by neutrophils is a hallmark of the chronic inflammatory skin disease psoriasis, yet the mechanisms underlying neutrophil recruitment and positioning in chronically inflamed skin rem...
link.springer.com
February 21, 2025 at 5:10 PM
Excited to share our new paper🚨📝
We explored SLPI's role in neutrophil migration in psoriasis!
Full paper: link.springer.com/article/10.1...
Big thanks to co-authors! 🙌
#neutrophils #inflammation #psoriasis #SLPI
We explored SLPI's role in neutrophil migration in psoriasis!
Full paper: link.springer.com/article/10.1...
Big thanks to co-authors! 🙌
#neutrophils #inflammation #psoriasis #SLPI