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Michel Nivard @michelnivard.bsky.social · 16m

the Synthetic Kingdom of Great Britain and Northern Ireland Biobank sounds a little subversive somehow...

Michel Nivard @michelnivard.bsky.social · 18m

UK Synthbank? UK Simulbank? Synthetic Kingdom Biobank? (to be VERY clear this is for people to trial there methods pipelines, not one of those insane ideas of relacing real data with synthetics...)

Michel Nivard @michelnivard.bsky.social · 24m

Synthetic non-parametric UKB phenotypes straight from an R package. It pulls all the required summary data from the UKB website.. Somewhat tempted to go totally overboad and have it simulate synthetic genomes, with plausible SNP h2's and "real" top hits (which i'd pull from GWAS cat & nealelab)..

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Michel Nivard @michelnivard.bsky.social · 22m

Actually it is parametric, but it cycles agnostivall trough a bunch (mixture) models making sure the quantiles and extreme's match...

Michel Nivard @michelnivard.bsky.social · 24m

Synthetic non-parametric UKB phenotypes straight from an R package. It pulls all the required summary data from the UKB website.. Somewhat tempted to go totally overboad and have it simulate synthetic genomes, with plausible SNP h2's and "real" top hits (which i'd pull from GWAS cat & nealelab)..

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Michel Nivard @michelnivard.bsky.social · 5h

I am thinking ppl can use it to test code, pipelines etc. @dsquintana.bsky.social didnt you have a syth data package I could potentially pipe this into so I dont have to rebuild the core mechanics?

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Michel Nivard @michelnivard.bsky.social · 5h

QUESTION 🚨: I wrote code that uses methods of moments too generate realistic synthetic data for a UKB trait from the showcase page. I might be able too add corelation between traits (have to find a source) to allow multivariate synth data, is this usefull enough to wrap in an R package??

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Michel Nivard @michelnivard.bsky.social · 2d

reducing it to its most absurd could be an amazing way to highlight the silly...

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Michel Nivard @michelnivard.bsky.social · 2d

I am in Berlin near the Max planck(s?) for a conference till thursday, LMK if any of you in the bluesky science-o-sphere want to meet (very limited availability, not cos I am cool and all booked up but just tired and old).

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Michel Nivard @michelnivard.bsky.social · 2d

I was thinking Sam Altman’s Dutch Alt, “Simon Oudemans”… why aim low with Nature I was thinking NEJM…

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Michel Nivard @michelnivard.bsky.social · 2d

I want to write this as a troll now… prob best under pseudonym…

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Michel Nivard @michelnivard.bsky.social · 2d

someone is going to do the perverted inverse and try to replace RCTs with LLMs: “we prompted llama 3.3 71b with: ‘you have just taken a semaglutide inection; outline your meals for this week’ and proceeded to compute weight change as 1 kg loss/gain per 7000kcal under daily recommended intake”

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Michel Nivard @michelnivard.bsky.social · 2d

It was a glorious 6 weeks for Old Navy Dads..

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Michel Nivard @michelnivard.bsky.social · 3d

There is that quote about religion being the opium of the masses? (I am surely bastardizing it here…)

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Michel Nivard @michelnivard.bsky.social · 3d

I was here with a 6 and 8 year old so they sprinted past and I had no time to dig into the what/why/how…

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Michel Nivard @michelnivard.bsky.social · 3d

There is a Dutch museum about all religions, they also cover post religious pseudo religious play, including Warhammer (?) (cc @lastpositivist.bsky.social warhammer as post religion cosplay, could be a thesis is all I am saying..)

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Michel Nivard @michelnivard.bsky.social · 4d

I have even seen really creative work using generative models. This is just about the dumbest idea possible…

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Michel Nivard @michelnivard.bsky.social · 4d

Yes, I think many of the writeups of crucial AI critiques labor under the weight of wanting to pack in all the critiques into every writeup…. There is a very narrow, specific, obvious and transparent reason “silicon samples” are really fucking dumb, and it’s clearest when made to stand on its own…

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Michel Nivard @michelnivard.bsky.social · 4d

;

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Michel Nivard @michelnivard.bsky.social · 5d

ERC Advanced applications from the US up from 23 on ‘24 to 114 in ‘25. Up a lot, but at a high funding rate this would be 12-25 US scientists, that’s a handful per country. This is ERV advanced, these ppl are likely tenured, ERC starter could attack younger ppl who are on TT could be be way bigger

lastpositivist.bsky.social @lastpositivist.bsky.social · 5d

This is probably a desired goal for the Trump regime? They have inconsistent preferences mind you so there's another sense in which this is undesired. But "drive out the intelligentsia and weaken academia" is, under this aspect, a favoured policy goal of theirs.

www.politico.eu/article/euro...

Top US researchers rush to relocate to Europe

U.S.-based applicants to a prestigious EU research scheme have increased five-fold.

www.politico.eu

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Michel Nivard @michelnivard.bsky.social · 5d

Yeah it is, if I try to graciously read it it’s about the bluesky wild comment section problem outlined in the first post. Good thing the protocol is open and you are seeing things like blacksky and north ky where ppl can be in community with all of bluesky, but with their own mods & on their terms

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Michel Nivard @michelnivard.bsky.social · 5d

It starts in this thread. bsky.app/profile/jay....

Jay 🦋 @jay.bsky.team · 7d

Too real. We’re going to try to fix this. Social media doesn’t have to be this way.

Jerry Chen @jcsalterego.bsky.social · 12d

(bluesky user bursts into Waffle House) OH SO YOU HATE PANCAKES??

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Michel Nivard @michelnivard.bsky.social · 5d

Yeah I wish we could shear the models (within their limits) from the Silicon Valley hype train… compressing the joint probability distribution of language is kind of amazing…

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Michel Nivard @michelnivard.bsky.social · 6d

You hand draw QR codes for the URLs I think…

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Michel Nivard @michelnivard.bsky.social · 6d

as do I, but my institution hates it and I cant really run a life where thers cant invite me to meetings while I also see my fam and kids calendars in parrallel.... Is there something German about this where like with cash you all dont do digital event invites for everything?

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Michel Nivard @michelnivard.bsky.social · 6d

Now I wonder what size "shove" the linkedin algorithm would need to actualy flip into like tumblr...

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