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Keshav K Singh, PhD

@mitoscientist.bsky.social

320 followers 370 following 100 posts

Longevity l Longevity Biotech l Longevity Medicine l Healthy Aging l Mitochondriac l Thought Leader l Author l Founder l Keynote Speaker l Entrepreneur l Healthquity I Undoing Aging Account: Personal l Repost: Not Endorsement

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Keshav K Singh, PhD @mitoscientist.bsky.social · Jan 19

Reversing Age-Related Wrinkles and Hair Loss youtu.be/tX0Vzb_Axss via @YouTube

youtu.be/tX0Vzb_Axss?...

Reversing Age-Related Wrinkles and Hair Loss

YouTube video by Cosmetic Laser Dermatology

youtu.be

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Keshav K Singh, PhD @mitoscientist.bsky.social · 1d

Reposted by Keshav K Singh, PhD

Catalina Vasilescu, PhD @cvasilescu.bsky.social · 4d

#MitochondrialDisease papers from #week40! 📚 💚
biomed.news/bims-mitdis/...

@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social

A few highlights below! 👇

DDHD2 provides a flux of saturated fatty acids for neuronal energy and function
www.nature.com/articles/s42...

DDHD2 provides a flux of saturated fatty acids for neuronal energy and function - Nature Metabolism

Saber et al. show that the lipase DDHD2 provides endogenous saturated fatty acids to support fatty acid oxidation and energy production, proteostasis and membrane trafficking balance.

www.nature.com

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Keshav K Singh, PhD @mitoscientist.bsky.social · 7d

Delighted to participate in the exciting
symposium on "Artificial Intelligence in
Mitochondrial Medicine: emerging tools for diagnosis and monitoring

Hotel Galilei
January 23rd,2026
Pisa,Italy

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Reposted by Keshav K Singh, PhD

Catalina Vasilescu, PhD @cvasilescu.bsky.social · 11d

#MitochondrialDisease papers from #week39! 📚 👇
biomed.news/bims-mitdis/...

@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social

A few highlights below!

Ribonucleotide incorporation into mitochondrial DNA drives inflammation - Nature

Imbalanced nucleotide metabolism leads to age- and mtDNA-dependent inflammatory responses and senescence-associated secretory phenotype in senescence.

nature.com

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Reposted by Keshav K Singh, PhD

Catalina Vasilescu, PhD @cvasilescu.bsky.social · 18d

To honour the #MitochondrialDisease #AwarenessWeek 💚 we bring a new collection of recently-published research papers related to mitochondrial disease:
biomed.news/bims-mitdis/...

@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social

Cryo-EM of the prohibitin complex

Hong et al, Cryo-EM structure of the prohibitin complex in open conformation

https://www.pnas.org/doi/10.1073/pnas.2512430122

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Keshav K Singh, PhD @mitoscientist.bsky.social · 18d

Tonight, shine a light of hope in green to support the mito community.

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Keshav K Singh, PhD @mitoscientist.bsky.social · 20d

This week (Sept 15 to 21, 2025) is Mitochondrial Disease Week
-a chance to shine light on mitochondrial disorders and the people living with them.
Light up green for mito on 20th, September.

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Keshav K Singh, PhD @mitoscientist.bsky.social · 22d

💚 September 15–21 is Mitochondrial Disease Awareness Week—a time to spotlight rare but serious conditions that affect the body’s energy “powerhouses.” Let’s stand with the mito community and help raise awareness for patients, families, and research.
#MitochondrialDisease #Awareness #Health

Keshav K Singh, PhD @mitoscientist.bsky.social · Sep 7

The amazing mitodancer! The real mito energy! 😂😂

Reposted by Keshav K Singh, PhD

Catalina Vasilescu, PhD @cvasilescu.bsky.social · Sep 7

Wonderful selections of papers on #MitochondrialDisease from #week35 and #week36! 📚

biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...

@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social

RTN4IP1 required for the final stages of mito CI assembly and CoQ synthesis

Olahova et al, RTN4IP1 is required for the final stages of mitochondrial complex I assembly and CoQ biosynthesis

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Keshav K Singh, PhD @mitoscientist.bsky.social · Sep 6

Stay calm and research on. 😂😂

Keshav K Singh, PhD @mitoscientist.bsky.social · Sep 1

💚 September 15–21 is Mitochondrial Disease Awareness Week-a time to spotlight diseases that are primarily due to defect(s)in mitochondria. Let’s stand with the mito community and help raise awareness for patients, families, and research.
#MitochondrialDisease #Awareness #HealthAdvocacy

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Reposted by Keshav K Singh, PhD

Catalina Vasilescu, PhD @cvasilescu.bsky.social · Aug 24

Last two weeks of literature relevant for #MitochondrialDisease! 📚

@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social @mitoscientists.bsky.social

Please browse the collections here! 👇
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...

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Keshav K Singh, PhD @mitoscientist.bsky.social · Aug 19

Faulty mitochondria don’t just sap energy—they spark brain inflammation. Together, they fuel Alzheimer’s, Parkinson’s & ALS. Our new article in Frontiers in Aging explains.

#Neuroscience #Aging #Neuroinflammation #Mitochondria #FrontiersInAging

www.frontiersin.org/journals/agi...

Frontiers | Pathogenic synergy: dysfunctional mitochondria and neuroinflammation in neurodegenerative diseases associated with aging

The term “neurodegenerative diseases” (NDDs) refers to a range of aging-associated conditions, including Alzheimer’s disease, Parkinson’s disease, and amyotr...

www.frontiersin.org

Keshav K Singh, PhD @mitoscientist.bsky.social · Aug 18

Reposted by Keshav K Singh, PhD

Catalina Vasilescu, PhD @cvasilescu.bsky.social · Aug 10

#MitochondrialDisease collection of papers from #week32! 📚
biomed.news/bims-mitdis/...

@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social

Highlights

Hypoxia ameliorates neurodegeneration and movement disorder in a mouse model of Parkinson's disease

Marutani et al, Hypoxia ameliorates neurodegeneration and movement disorder in a mouse model of Parkinson's disease
https://www.nature.com/articles/s41593-025-02010-4

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Keshav K Singh, PhD @mitoscientist.bsky.social · Aug 5

Join us in India for an exciting meeting on mitochondria in health, disease, and aging, Oct 9 to 11, 2025, at Manipal University, Manipal.

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Reposted by Keshav K Singh, PhD

Catalina Vasilescu, PhD @cvasilescu.bsky.social · Aug 3

Wonderful selection of papers on #MitochondrialDisease from #week31!
biomed.news/bims-mitdis/...

@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social

A few highlights below, many more inside!
www.nature.com/articles/s42...

2-hydroxyglutarate mediates whitening of brown adipocytes coupled to nuclear softening upon mitochondrial dysfunction - Nature Metabolism

CLPP-deficiency-driven mitochondrial dysfunction in brown adipose tissue leads to the accumulation of d-2-hydroxyglutarate, in turn promoting lipid-droplet enlargement by altering gene expression and ...

www.nature.com

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Reposted by Keshav K Singh, PhD

Kristina Killgrove @killgrove.bsky.social · Aug 2

If I may put on my ex-academic hat today, I have a new peer-reviewed article out in the J of Mediterranean Archaeology! We did an mtDNA analysis of people buried at Gabii over the span of about a millennium. 🏺🧪

Mitochondrial DNA Evidence for Community Building and Population Dynamics at a Multi-Phase Roman Site (Gabii, Italy, 8th Century BC– 2nd Century AD) | Journal of Mediterranean Archaeology ...

journal.equinoxpub.com