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Keshav K Singh, PhD

@mitoscientist.bsky.social

November 28, 2025 at 6:27 AM

Keshav K Singh, PhD

@mitoscientist.bsky.social

Embracing my silly side makes me a better scientist. I wish I’d done it sooner | Science | AAAS www.science.org/content/arti...

Embracing my silly side makes me a better scientist. I wish I’d done it sooner

Humor has helped this professor connect with students and colleagues—and remain resilient during hard times

www.science.org

November 25, 2025 at 10:07 PM

Reposted by Keshav K Singh, PhD

KLAB - finding a cure for GI dysmotility at #HarvardStrong

@klab.bsky.social

#NIH modified how next peer review panel will #review #grants

grants.nih.gov/news-events/...

Emergency Modifications to NIH Peer Review | Grants & Funding

grants.nih.gov

November 25, 2025 at 7:33 PM

Reposted by Keshav K Singh, PhD

Tanya Joosten

@tanyajoosten.bsky.social

NIH shake-up to grant decision-making draws concerns of political meddling | Science | AAAS www.science.org/content/arti...

NIH shake-up to grant decision-making draws concerns of political meddling

Policy drops “paylines” based on peer-review scores and requires geography and other factors to guide approvals

www.science.org

November 25, 2025 at 6:31 PM

Reposted by Keshav K Singh, PhD

Trisha Clark

@tcinindy.bsky.social

This is concerning…. Based on their new policy, NIH can stop providing reasoning for rejecting high-scoring proposals. #RAdminsky

Jeremy Berg @jeremymberg.bsky.social · 4d

This is concerning.

NIH is changing their policy so that staff have to prepare justification for every application that is funded BUT NO DOCUMENTATION FOR APPLICATIONS THAT ARE SKIPPED (BASED ON PERCENTILES).

1/2

An internal document from NIH which states that documentation must be provide for each funded grant but that no documentation need be provided for applications that are not selected for funding including those that are skipped back on overall impact scores.

November 24, 2025 at 1:24 AM

Reposted by Keshav K Singh, PhD

E.B. Howard Consulting

@ebhc.bsky.social

NIH abruptly paused SBIR and STTR activity, creating uncertainty for applicants who now require strategy, preparation, and airtight…

https://www.ebhoward.com/nih-hits-pause-on-sbir-and-sttr-what-the-latest-guidance-means-for-your-funding-strategy/?utm_source=bluesky&utm_medium=jetpack_social

November 24, 2025 at 1:19 PM

Reposted by Keshav K Singh, PhD

quadrapole.bsky.social

@quadrapole.bsky.social

NIH Grant Update -

"All grant applications submitted late for due dates between October 1, 2025, and December 5, 2025, will be accepted through 5:00 PM local time December 8, 2025."

grants.nih.gov/grants/guide...

NOT-OD-26-012: Updated Guidance on Reopening of NIH Extramural Activities Following the October 1, 2025 - Lapse in Appropriations

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Updated Guidance on Reopening of NIH Extramural Activities Following the October 1, 2025 - Lapse in Appropriations NOT-...

grants.nih.gov

November 24, 2025 at 6:16 PM

Reposted by Keshav K Singh, PhD

Princess Vimentin PhD | Cancer Biologist

@princess-vimentin.bsky.social

🧪PSA
New notices of #NIH awards now have language allowing grants to be terminated if they no longer “align” with agency “priorities”. This will create uncertainty b/c we can’t count on funding if it can be arbitrarily terminated while a study is in progress.
Via @jenna-m-norton.bsky.social on IG

November 24, 2025 at 6:48 PM

Reposted by Keshav K Singh, PhD

Ran Blekhman

@blekhman.bsky.social

Due to the shutdown, NIH cancelled >370 study sections, impacting >24,000 applications

Rescheduled meetings will only discuss 30-35% of applications, have simplified summary statements (no narrative paragraph), and a new category - "competitive but not discussed"

grants.nih.gov/grants/guide...

NOT-OD-26-012: Updated Guidance on Reopening of NIH Extramural Activities Following the October 1, 2025 - Lapse in Appropriations

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Updated Guidance on Reopening of NIH Extramural Activities Following the October 1, 2025 - Lapse in Appropriations NOT-...

grants.nih.gov

November 24, 2025 at 6:55 PM

Reposted by Keshav K Singh, PhD

Karen Benjamin Guzzo

@karenguzzo.bsky.social

New NIH guidance related to the shutdown. One of the changes is that "the percent of applications discussed in most meetings will be reduced to 30-35%, instead of the current ~50%."

NOT-OD-26-012: Updated Guidance on Reopening of NIH Extramural Activities Following the October 1, 2025 - Lapse in Appropriations

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Updated Guidance on Reopening of NIH Extramural Activities Following the October 1, 2025 - Lapse in Appropriations NOT-...

grants.nih.gov

November 24, 2025 at 7:18 PM

Keshav K Singh, PhD

@mitoscientist.bsky.social

November 24, 2025 at 5:27 AM

Reposted by Keshav K Singh, PhD

Catalina Vasilescu, PhD

@cvasilescu.bsky.social

Rich collections of papers on #mitochondrialdisease from the last 2 weeks! 📚
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...

@biomednews.bsky.social @mitoscientist.bsky.social
@gavinmcstay.bsky.social

Demethoxy-CoQ and NUDT5 in nucleotide synthesis
www.nature.com/articles/s42...

Uridine-sensitized screening identifies demethoxy-coenzyme Q and NUDT5 as regulators of nucleotide synthesis - Nature Metabolism

A uridine-sensitized CRISPR-Cas9 screening identifies demethoxy-CoQ as an alternative electron acceptor in the absence of CoQ, and NUDT5 as a regulator of de novo pyrimidine synthesis via its interact...

www.nature.com

November 23, 2025 at 11:59 AM

Reposted by Keshav K Singh, PhD

M. S. AtKisson

@igrrrl.bsky.social

Goodbye NIH SBIR/STTR: “Legislative authority for the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs expired on October 1, 2025.”

grants.nih.gov/grants/guide...

NOT-OD-26-006: Notice of Early Expiration of NIH Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Notices of Funding Opportunity and Guidance for Existing Recipi...

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Early Expiration of NIH Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STT...

grants.nih.gov

November 22, 2025 at 12:47 PM

Keshav K Singh, PhD

@mitoscientist.bsky.social

The NIH percentile-based funding system ends January 2026. ICOs will evaluate applications using the full scope of peer-review feedback—not rigid paylines. Funding decisions will instead be driven by NIH and ICO strategic priorities, scientific needs, and budget realities.

grants.nih.gov/news

Implementing a Unified NIH Funding Strategy to Guide Consistent and Clearer Award Decisions | Grants & Funding

grants.nih.gov

November 22, 2025 at 3:59 PM

Keshav K Singh, PhD

@mitoscientist.bsky.social

November 18, 2025 at 5:11 AM

Keshav K Singh, PhD

@mitoscientist.bsky.social

November 15, 2025 at 2:31 AM

Keshav K Singh, PhD

@mitoscientist.bsky.social

I’m happy to share that I’m starting a new position as Member Scientific and Medical Advisory Board at Countdown For A Cure!

share.google/1cP0QpeTRrRf...

Scientific Advisory Board – Countdown For A Cure

share.google

November 14, 2025 at 5:56 AM

Keshav K Singh, PhD

@mitoscientist.bsky.social

Multilingualism is associated with a reduced risk of accelerated aging, according to data from more than 86,000 people across 27 European countries published in Nature Aging. The findings suggest that promoting multilingualism could support healthy aging.

www.nature.com/articles/s43...

Multilingualism protects against accelerated aging in cross-sectional and longitudinal analyses of 27 European countries - Nature Aging

In cross-sectional and longitudinal analyses of 86,149 participants across 27 European countries, Amoruso, Hernandez and colleagues identify multilingualism as a protective factor against accelerated ...

www.nature.com

November 14, 2025 at 4:11 AM

Keshav K Singh, PhD

@mitoscientist.bsky.social

November 12, 2025 at 5:01 AM

Reposted by Keshav K Singh, PhD

Annika Barber

@annikabarber.bsky.social

Up to 323 cancelled CSR study sections. That's more than the 204 sections cancelled earlier this year. Rescheduling is going to be a hot mess with NIH staff reductions and study section members heading into finals and holidays that limit availability. 🧪

Annika Barber @annikabarber.bsky.social · Oct 21

Been a rough year for federally funded scientists, and I hate to add another tab to this spreadsheet. So far, the shutdown has resulted in cancellation of 161 CSR study sections. 🧪https://docs.google.com/spreadsheets/d/1lLEx14q7HKrlYahQYJaN6aHKpMqSMJwX4aenyL5g_ZU/edit?usp=sharing