Lightnews — Scholar-powered news

Moritz Treeck @moritztreeck.bsky.social · Sep 8

You are always welcome:) Next time we'll ensure there is beach weather!

Moritz Treeck @moritztreeck.bsky.social · Aug 30

David Jones PhD manuscript on how mild heat stress (experienced during fever episodes in most malaria infections)changes the cytoadhesion behavior of parasite infected red blood cells is now online and reviewed in eLife.

elifesciences.org/reviewed-pre...

Physiological febrile heat stress increases cytoadhesion through increased protein trafficking of Plasmodium falciparum surface proteins into the red blood cell

elifesciences.org

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Moritz Treeck @moritztreeck.bsky.social · Jul 2

Congrats Matt! Very well deserved.

Reposted by Moritz Treeck

Hugo Belda @hbelda.bsky.social · Jun 23

Better late than never, but I am thrilled to share our newest research from the Treeck lab!!! www.nature.com/articles/s41...

The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound - Nature Microbiology

FIKK effector kinases underwent rapid evolutionary expansion and are a druggable target in Plasmodium falciparum.

www.nature.com

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Moritz Treeck @moritztreeck.bsky.social · Jun 23

thanks to @stephanienofal.bsky.social, @hbelda.bsky.social, Gwendolin Fuchs, Goska Broncel, @danaguano.bsky.social

Thanks for funding from the
@erc.europa.eu
@crick.ac.uk
@wellcometrust.bsky.social
and the FCT

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Moritz Treeck @moritztreeck.bsky.social · Jun 23

What happens when the parasite that causes malaria in humans experiences fever-induced heat stress in its host red blood cell?

Check out David Jones' PhD work now on BioRxiv

www.biorxiv.org/content/10.1...

www.biorxiv.org

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Reposted by Moritz Treeck

Nonia Pariente @npariente.bsky.social · Jun 20

Excellent and thought-provoking. A highly recommended read

Brian Klaas @brianklaas.bsky.social · Jun 19

After the latest round of grading papers, I wrote about AI, ChatGPT, the death of the student essay, and what it means for the future of human cognition.

The Death of the Student Essay—and the Future of Cognition

One professor's reflections on the end of an era, as AI tools such as ChatGPT have murdered the student essay (RIP). Here's why that threatens the future of human cognition—and how to save ourselves.

www.forkingpaths.co

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Moritz Treeck @moritztreeck.bsky.social · Jun 16

Really cool work! Congrats all!

Sam Chamberlain @sam-chamberlain.bsky.social · Jun 12

Extremely happy to share the first paper of my postdoc work with @parasitematt.

It is the product of a great collaboration with Akihito Sakoguchi, Hisashi Arase and Shiroh Iwanaga at Osaka University as well as Marcus Widdess and Mike Dustin here in Oxford.

rdcu.be/eqx2J

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Moritz Treeck @moritztreeck.bsky.social · Jun 9

👏!

Moritz Treeck @moritztreeck.bsky.social · Jun 3

GIMM PhD Programme now open. 17 PhD positions and a few more to come.

gimm.pt/course/phd-p...

GIMM PhD Studentships 2025 – GIMMGIMM PhD Studentships 2025 – GIMM

Thank you very much for your generous donation and for sharing your testimony.We hope to more people feel inspired to join this mission of discovery and innovation!

gimm.pt

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Moritz Treeck @moritztreeck.bsky.social · Jun 2

This is SO important!

veupathdb.org @veupathdb.org · Jun 2

Make open access to tools and data part of your annual giving by making a tax deductible donation to @veupathdb.org. 💙This resource simplifies and supercharges global infectious disease research.

Need more reasons to support VEuPathDB? Here's a short list: veupathdb.org/veupathdb/ap...

Moritz Treeck @moritztreeck.bsky.social · May 20

👏

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Moritz Treeck @moritztreeck.bsky.social · May 19

@christianlandry.bsky.social, @ljwalport.bsky.social, @ant1-claessens.bsky.social, @stephanienofal.bsky.social, and all our Bluesky-less collaborators from the lab, @crick.ac.uk and @glaxosmithkline.bsky.social and @erc.europa.eu, @crick.ac.uk and @gimmfoundation.bsky.social for funding and hosting

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Moritz Treeck @moritztreeck.bsky.social · May 19

Many thanks to many collaborators, without whom this almost 10 year effort (the structure was hard to crack!) would have been impossible to achieve. 3/n

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Moritz Treeck @moritztreeck.bsky.social · May 19

For the aficidinados of evolution of kinases in general, those interested in this kinase family in field isolates and their role in host-pathogen interaction, their unusual structure, to finding a starting point for collective inhibiton: there is lot's to read in the paper.

2/n

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Moritz Treeck @moritztreeck.bsky.social · May 19

Huge congratulations to @hbelda.bsky.social and David Bradley for their publication on the extraordinarily interesting FIKK kinase family (I am biased) of the malaria causing parasite Plasmodium falciparum. 1/n

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Moritz Treeck @moritztreeck.bsky.social · May 8

Dislike!
But congratulations of course!!

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Moritz Treeck @moritztreeck.bsky.social · Apr 26

Great work!

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Moritz Treeck @moritztreeck.bsky.social · Apr 26

Congrats- great work!

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Moritz Treeck @moritztreeck.bsky.social · Apr 22

Congrats Eva - great news!

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Moritz Treeck @moritztreeck.bsky.social · Apr 17

The more we learn about Toxoplasma virulence factors, the more interesting questions pop up! This is one of ~250 proteins the parasites secretes into the host cell, or in the vacuole the parasite lives in. Much more to discover!

Happy Easter all!

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Moritz Treeck @moritztreeck.bsky.social · Apr 17

A common virulence factor that protects Toxoplasma (and probably related parasites) from clearance in genetically diverse murine hosts. A heroic CRISPR screening effort from @fratorelli.bsky.social with some help from colleagues. Thanks to anonymous reviewers for some good suggestions.
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Francesca Torelli @fratorelli.bsky.social · Apr 16

🎉 Finally online 🎉 GRA12, the first identified common virulence factor across Toxoplasma strains and murine subspecies! Check this improved manuscript after reviewers’ helpful suggestions www.nature.com/articles/s41...

GRA12 is a common virulence factor across Toxoplasma gondii strains and mouse subspecies - Nature Communications

CRISPR screens reveal Toxoplasma’s GRA12 as a strain- and mouse species-transcendent virulence factor. GRA12 protects parasites from IFNγ-activated macrophage clearance and parasitophorous vacuole col...

www.nature.com

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Moritz Treeck @moritztreeck.bsky.social · Apr 10

Open call for 3 Group Leader Positions at the newly formed GIMM in Lisbon! Strong core facilites, Science across many disciplines + Sunshine, Beaches and the Atlantic.

Link to call here

gimm.pt/jobs/open-ca...

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Moritz Treeck @moritztreeck.bsky.social · Apr 4

m6A modifications in sexual differentiation of the malaria causing parasite Plasmodium falciparum. Bravo team Baumgarten and colleagues!

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Reposted by Moritz Treeck

Karina Xavier Lab @karinaxavierlab.bsky.social · Mar 16

Symbnet PhD Summer School on Host-Microbe Symbioses - Oeiras Portugal. Students from all over the world are eligible, we sponsor selected students. Please Repost!
gimm.idloom.events/phd-summer-s...

PhD Summer School on Host-Microbe Symbioses 2025

Symbnet PhD Summer School on Host-Microbe Symbioses Gulbenkian Institute for Molecular Medicine (GIMM) & Católica Biomedical Research Centre (CBR) July 06...

gimm.idloom.events

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