Interesting case study on the #mRNA consortium managed by @who.int + @medicinespatentpool.org. Initially focused on manufacturing capacity for pandemic #vax, its sustainability, effective capacity building in #LMIC and free market approach remain contentious #mRNApolicy #mRNAmanufature

🤓 Interesting read for science and health policy nerds out here: round-up of #mRNA #vaccine tech, current developments and challenges (old and new) of this promising technology #mRNAupdate #mRNApolicy

How #mRNA tech could be life-changing for treating rare diseases: adaptability and targeted protein expression capacity as possible routes to develop treatments for rare diseases. Affordability and access equity remains a challenge for people living with rare diseases in #LMIC #mRNAupdate

Based on successful experiences, #Gavi coordinated investment, pooled procurement and strong regulatory capacity pointed as essential steps for establishing end-to-end vaccine manufacturing ecosystem in the #African continent - including #mRNA capacity #mRNAmanufacture #mRNApolicy

self-amplifying #mRNA Covid-19 vax entering the #EU market - interesting dynamics on market share and development process landscape for the next genaration of #mRNAvaccines #mRNAupdate

Ecosystem development for #mRNA vax in the African continent: push for building end-to-end capacity contrasts with initiatives that did not take off since the Covid-19 pandemic #mRNApolicy #mRNAmanufacture

Interesting read: a summary of @who.int #PAHO and @medicinespatentpool.org led meeting on investment opportunities for #mRNA in LMIC. Multilateral Dev. Banks cite de-risking, inter-pandemic sustainability and a multilayered system strengthening - including regulation, HR - as way forward #mRNApolicy

Vaccine development in #Brazil: @oficialfiocruz.bsky.social Bio Manguinhos proprietary #mRNA COVID-19 vax is on track to finish last step before clinical trials. Fiocruz's platform was initially focused on developing treatment options for difficult-to-treat breast cancer #mRNAmanufacture #PTBR

trends and challenges for RNA in 2025: adapting #mRNA platforms to innovate beyond vaccines, balancing small-batch and high-output production scales, and harmonising the global regulatory pathways are pointed as the main obstacles for development #mRNApolicy #mRNAmanufacture

On the cusp of a breakthrough: #USA and #China leading the development of #mRNA based therapies to fight cancer. #mRNAupdate

Predictable demand is key to thriving regional vaccine production. It unlocks investments, reduces vaccine uncertainty and builds market confidence.
Read more on the RVMC website. #RVMC
rvmc.net/call-predict...

Innovation in the #globalsouth: @oficialfiocruz.bsky.social researchers Patrícia Neves and Ana Paula Ano Bom developed their own mRNA COVID-19 vax and plan to share the tech for free, overcoming #pharma monopolies that exacerbated the impact of the covid pandemic in LMICs #mRNAtech #mRNApolicy #BR

On the complex network of R&D and capacity building: the role of contract development and manufacturing organizations (CDMO) in upscaling #mRNA manufacturing and innovation capacity. #mRNAupdate

Worth the read: @wemos.org case study on BioNtech's Africa mRNA hub. More needs to be done to ensure countries' sovereignty and self-reliance, including effectively transferring tech capacity and attaching conditions when public funding is involved. #mRNApolicy #mRNAmanufacture

mRNA tech news: @upenn.bsky.social and the Children’s Hospital of Philadelphia have developed the first mRNA vaccine against C. difficile to successfully ward off the bacterial infection. #mRNA alternatives to difficult-to-treat bacterial infections #mRNAupdate #ENG

"This MoU represents a commitment to advance the development of RNA-based vaccines and therapies, expanding access to innovative health solutions both regionally and globally" @oficialfiocruz.bsky.social #Br #Belgium #mRNAmanufacture #ENG

mRNA tech news: Cooking Up a Breakthrough: @upenn.bsky.social Engineers Refine Lipid Nanoparticles for Better mRNA Therapies #mRNA #ENG #mRNAupdate