You misspelled Fellowship Committee.😉

Franz Arnold Ake from @idibell.bsky.social presented SCALPEL, a Nextflow-based pipeline to quantify and characterize isoforms at single-cell resolution. Fascinating work that will be applied to study alternative polyadenylation during neural differentiation and neurodegenerative diseases.🧠

Thank you for the interesting evening with beers, science, and nice company (and in my case: a free (scientific) Spanish practice session).

Thx @dhdegroot.bsky.social for troubleshooting my submission. ❤️

@shaunmahony.bsky.social & @erikvannimwegen.bsky.social: I submitted a sample from doi.org/10.15252/msb... to Bonsai and this is what I got.
You can explore the dataset here: bonsai.unibas.ch/bonsai-scout....
My code and comments can be found at codeberg.org/mschilli/bon....

PS: I also like the name but it's clearly not the best in terms of SEO. 😉

Doesn’t change the fact that I like the idea of Bonsai. In the case of cell cycle I might be more cautious then when analyzing a differentiation dataset, but if IIRC, Schwabe et al. found that UMAP doesn’t find the circle either.

We might not *know*, but we do have some good arguments that they actually might: doi.org/10.15252/msb...

Wow! One day, two celebrations. I hope you had an opportunity to celebrate. 🍻

…using Python 😉

Python? 😉😅