Finally, we show that other neurons in the accessory medulla also exhibit coherent membrane potential oscillations, with diverse lags, suggesting the intriguing possibility that brain waves may arise from collective neuronal activity in this region of the fly brain 🤩(6/7)

small-LNvs oscillate behind large-LNvs with a consistent lag, so we went back to the theory and established relations between parameter values and observables such as the amplitude and phase lag of the forced oscillations (5/7)

The forced oscillator theory not only fits but also predicts features such as: “neurons of different type may present lags in their oscillations”. So @lforencia.bsky.social did lots of very difficult patch recording of LNv pairs 🙌, and found exactly that! (4/7)

… oscillations depend on cholinergic inputs. Accordingly, we found a phase response curve to be flat (this is odd, said the physicists!) so to model this, we introduce a generic theory for a forced oscillator that describes key aspects of the oscillatory dynamics! (3/7)

We first show you the longest, higher quality, better-analyzed patch clamp recordings of LNvs to date 😎, not only from large-, but also small-LNvs. We found that they both display consistent oscillations, but these are not cell-autonomous…(2/7)

Are #Drosophila accessory medulla neurons oscillating coherently? Out today @cp-iscience.bsky.social “Neuronal Synchronization in Drosophila”, featuring DUAL patch clamp recordings from the great @lforencia.bsky.social and impeccable theory by oscillation experts Marcos Wappner & Luis Morelli (1/7)