Mustjoki Laboratory
@mustjoki-lab.bsky.social
Hematology Research Unit Helsinki - Mustjoki lab investigates autoimmunity and tumor immunology
🌍📍 University of Helsinki, Finland
🔗https://www.helsinki.fi/en/researchgroups/hematology-research-unit-helsinki
🌍📍 University of Helsinki, Finland
🔗https://www.helsinki.fi/en/researchgroups/hematology-research-unit-helsinki
Pinned
Our lab, led by Prof. Satu Mustjoki, investigates blood cancer cell interactions with immune effector cells. We also study how somatic mutations affect immune cell function in autoimmune diseases and cancer. Utilizing advanced technologies we aim to develop individualized treatment strategies.
Reposted by Mustjoki Laboratory
Excited to share our work on T&NK cells in autoimmunity, now out in SciTranslMed! www.science.org/doi/10.1126/...
We explored cells driving autoimmunity, searched for pathogenic TCRs & used single-cell seq in cohort of >200 pts to track them in co-culture with target cells.
1/
We explored cells driving autoimmunity, searched for pathogenic TCRs & used single-cell seq in cohort of >200 pts to track them in co-culture with target cells.
1/
Single-cell analysis of aplastic anemia reveals a convergence of NK and NK-like CD8+ T cells with a disease-associated TCR signature
NK cells and CD8+ TEMRA cells expressing NK receptors and disease-associated T cell receptors may drive autoimmunity in aplastic anemia.
www.science.org
February 28, 2025 at 6:30 AM
Excited to share our work on T&NK cells in autoimmunity, now out in SciTranslMed! www.science.org/doi/10.1126/...
We explored cells driving autoimmunity, searched for pathogenic TCRs & used single-cell seq in cohort of >200 pts to track them in co-culture with target cells.
1/
We explored cells driving autoimmunity, searched for pathogenic TCRs & used single-cell seq in cohort of >200 pts to track them in co-culture with target cells.
1/
Our lab, led by Prof. Satu Mustjoki, investigates blood cancer cell interactions with immune effector cells. We also study how somatic mutations affect immune cell function in autoimmune diseases and cancer. Utilizing advanced technologies we aim to develop individualized treatment strategies.
March 20, 2025 at 1:56 PM
Our lab, led by Prof. Satu Mustjoki, investigates blood cancer cell interactions with immune effector cells. We also study how somatic mutations affect immune cell function in autoimmune diseases and cancer. Utilizing advanced technologies we aim to develop individualized treatment strategies.