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Myra McGuinness @myramcguinness.bsky.social · 8d

It is difficult to find prospective comparative studies on many surgical interventions. I am working on a similar systematic review right now. Besides the issues relating to how problematic single-armed pre-post studies are, does anyone have any good references on when not to pool estimates?

Effectiveness and safety of cross-linking in keratoconus patients with corneal thickness <400μm: A systematic review and meta-analysis

Myra McGuinness @myramcguinness.bsky.social · 8d

Someone on here recently used a term like "paper laundering" when low quality evidence is included in meta-analyses. I'm pretty sure I am guilty of that here. In retrospect, perhaps we could have presented individual study estimates without a pooled estimate. >

www.ajo.com/article/S000...

In this systematic review and meta-analysis, we aimed to investigate the effectiveness and safety of corneal cross-linking (CXL) in patients with keratoconus and thin corneas (corneal thickness <400μm...

www.ajo.com

Combining information from trial participants and non-participants in registry-based trials

Myra McGuinness @myramcguinness.bsky.social · 15d

This week! Join us on Thursday for the September ViCBiostat seminar on stat methods for registry-based trials.

Myra McGuinness @myramcguinness.bsky.social · Aug 11

September @vicbiostat.bsky.social seminar:

Camila Olarte Parra from @causalab.bsky.social Karolinska will speak on combining information from trial participants and non-participants in registry-based trials.

All welcome online 25 September.

More info:
www.vicbiostat.org.au/event/combin...

Even though the advantages of randomised tria

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Myra McGuinness @myramcguinness.bsky.social · 17d

I went to visit his plaque in St Peter's when I was in Adelaide for a conference. He must have left tourist attractions all around the world.

Hope in Sight Giving Day 2025: Be a sport and help us end Usher syndrome

Myra McGuinness @myramcguinness.bsky.social · 19d

It hurt to have to pronounce the second w in Warwick when I lived there.

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Myra McGuinness @myramcguinness.bsky.social · 20d

Lovely video from my work about the motivation behind research into gene therapy for Usher syndrome. youtu.be/4Km9jZh_X1A?...

YouTube video by Centre for Eye Research Australia | CERA

youtu.be

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Myra McGuinness @myramcguinness.bsky.social · 23d

See you there 😀

Reposted by Myra McGuinness

whizzfizzlizz.bsky.social @whizzfizzlizz.bsky.social · 29d

Join us at #atmc25 as we explore "Better Trials Through Better Methods"
Invited speakers and program details now available - more at www.atmc25.com

Secure your ticket today! Early🐦 must end 26/9

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Myra McGuinness @myramcguinness.bsky.social · Sep 7

Review received this morning. Is this a weird sort of punishment for joking about Reviewer 2 last week?

Screenshot of text saying "2. Sentences should not begin with conjunctions such as 'however'."

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Myra McGuinness @myramcguinness.bsky.social · Sep 2

I am an easy marker for oral presentations because i am always amazed that people can say the right words in the right order. I learn from reading so there's a chance i will mention "poison" distributions if you hand me count data.

Myra McGuinness @myramcguinness.bsky.social · Sep 2

They can, as long as they use terms like multivariate, Likert, Rasch, and utilise correctly.

Myra McGuinness @myramcguinness.bsky.social · Sep 2

I didn't know there was a difference between used and utilised. I just looked it up and now I'm definitely going to bring it up next time I am Reviewer 2.

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Myra McGuinness @myramcguinness.bsky.social · Aug 27

For one building, MSPGH somehow teleports between Carlton, Parkville, and Melbourne.

Reposted by Myra McGuinness

Clinical Epi & Biostatistics Unit (CEBU) @cebu-melbourne.bsky.social · Aug 25

📢 Australian Trials Methodology Conference 2025
🗓 20 Nov | 📍Melbourne & Online via Zoom
Join leading speakers from academia, industry & healthcare.
🎟 Early-bird rates until 26 Sep!
🔗Register: atmc25.com
#ClinicalTrials #TrialMethodology #Biostatistics
@vicbiostat.bsky.social

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Myra McGuinness @myramcguinness.bsky.social · Aug 25

We haven't got a publically available recording. @jonathan-bartlett.bsky.social might have slides he can share?

Myra McGuinness @myramcguinness.bsky.social · Aug 22

Will this happen in Australia when our age restriction laws come into effect in December?

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Myra McGuinness @myramcguinness.bsky.social · Aug 22

Great news.

Myra McGuinness @myramcguinness.bsky.social · Aug 17

Yeah, tricky to find rare events in RCTs. Our next CERA stats-in-progress meeting is on meta-analyses of adverse events, using ozempic as an example.

Myra McGuinness @myramcguinness.bsky.social · Aug 15

Nice work! It annoying that those new studies call themselves cohort studies. These retrospective administrative data studies with vague site info are hard to incorporate into evidence synthesis work because its not clear if the patients have already been counted in the other published studies.

Combining information from trial participants and non-participants in registry-based trials

Myra McGuinness @myramcguinness.bsky.social · Aug 11

September @vicbiostat.bsky.social seminar:

Camila Olarte Parra from @causalab.bsky.social Karolinska will speak on combining information from trial participants and non-participants in registry-based trials.

All welcome online 25 September.

More info:
www.vicbiostat.org.au/event/combin...

Even though the advantages of randomised tria

G-formula for causal inference using synthetic multiple imputation

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Myra McGuinness @myramcguinness.bsky.social · Jul 23

We are looking forward to hearing @jonathan-bartlett.bsky.social speak on the G-formula for causal inference using synthetic multiple imputation at the July @vicbiostat.bsky.social seminar!

All welcome online Thursday 24th, 4:00pm Aus EST (7:00am UK time).

www.vicbiostat.org.au/event/g-form...

G-formula is a popular approach for estimatin

Research Assistant / Research Fellow in Bayesian Statistics

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Reposted by Myra McGuinness

MISCH hub @mischhub.bsky.social · Jul 14

🔍 Looking for your next big opportunity in Bayesian statistics? Join the team at Peter Doherty Institute for Infection and Immunity as a Research Assistant or Research Fellow in Bayesian analysis.

📍 Based in Melbourne | 💼 Apply now: unimelb.wd105.myworkdayjobs.com/UoM_External...

Role type: Full-time; Fixed-term for 2 years  Faculty: Faculty of Medicine, Dentistry and Health Sciences  Department/School: Department of Infectious Diseases Salary: Level A – $85,555 to $116,094 (P...

unimelb.wd105.myworkdayjobs.com

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Myra McGuinness @myramcguinness.bsky.social · Jul 11

Sometimes this is an indication that we could have communicated more clearly. If you are publishing in a clinical journal, assume a lot of the audience will need hand holding. Could follow term like dummy variable with "(i.e., an indicator of xxx)" to please reviewer and educate audience.

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Reposted by Myra McGuinness

MISCH hub @mischhub.bsky.social · Jul 10

🚨Join our team at the University of Melbourne as a RA/Research Fellow in Biostats. This is an exciting opportunity to contribute to impactful public health research within a supportive and collaborative environment.
📅 Applications close: 28 July 2025
👉 lnkd.in/gCRhts9K

Methods and Implementation Support for Clinical and Health research Hub hiring Research Assistant / Research Fellow in Biostatistics in Parkville, Victoria, Australia | LinkedIn

Posted 3:25:23 AM. Role type: Full-time; Fixed-term for 12 months (maternity cover)  Faculty: Faculty of Medicine…See this and similar jobs on LinkedIn.

lnkd.in