Natalie Chazal
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nataliechazal.info
Natalie Chazal
@nataliechazal.info
Reposted by Natalie Chazal
How well does TWAS estimate a gene’s direction of effect on a trait? We think of this as an important stress-test for the accuracy of TWAS.

In a new pre-print, we find that TWAS gets the sign wrong around 20-30% of the time!

doi.org/10.64898/202...

1/n
High false sign rates in transcriptome-wide association studies
Transcriptome-wide association studies (TWAS) are widely used to identify genes involved in complex traits and to infer the direction of gene effects on traits. However, despite their popularity, it r...
doi.org
January 6, 2026 at 2:30 AM
Reposted by Natalie Chazal
🚨New publication!🚨 We used high-resolution accelerometry biologging tags to quantify #graywhale behavior off the #Oregon coast at multiple scales (broad & fine).

Check it out in Marine Mammal Science: onlinelibrary.wiley.com/doi/10.1111/...

#biologging #tagging #marinemammals
Using accelerometry tags to quantify gray whale foraging behavior
High-resolution tri-axial accelerometry biologging tags have quantitatively described behaviors in baleen whale species that forage using lunges and continuous ram filtration. However, detailed quant...
onlinelibrary.wiley.com
December 9, 2024 at 7:15 PM