Nat Ketone
natkeytone.bsky.social
Nat Ketone
@natkeytone.bsky.social
Chemist and toxicologist. SPI with the Cardiff centre of the UK National Poisons Information Service/Toxbase. 🧪🍄💊🐍
Fortunately, methanol poisoning is quite rare in the UK. Because it’s rare, it’s not worth it for most hospitals labs to maintain the ability to test for it, so when it does happen the sample typically has to be sent by courier to one of five or six labs in the country that can do it
November 14, 2025 at 9:42 AM
Because ethanol blocks its metabolism, while you still have booze in your system you don’t suffer any toxicity. So if you’ve had a Big Night, it will be hours later (once the ethanol is out of your system) that you know anything is wrong - and often this will be when you’re sleeping the booze off
November 14, 2025 at 9:40 AM
Next year, I’m going as incorrect or missing units
October 31, 2025 at 12:49 PM
I cannot find anyone who said “my patient ingested 42 g camphor”, but that is consistently quoted as the highest survived dose
October 31, 2025 at 12:18 PM
People have tried nutmeg to get high. My understanding is that both the taste of the large quantities needed and the hallucinations themselves are unpleasant
October 15, 2025 at 12:04 PM
Not very permanent
September 9, 2025 at 5:02 PM
4) although this situation is safer than the others, the presence of lead deposits anywhere can cause raised lead levels, particularly if the granuloma around the fragment is later disturbed (e.g. by trauma) or migrates to a higher risk area; therefore
5) any lead in the body is potentially an issue
August 13, 2025 at 7:40 AM
1) lots of fluid moving over the fragment promoting dissolution
2) lots of bone turnover; as a large 2+ ion, lead looks similar to calcium to a lot of body processes
3) many small fragments have a higher surface area than one larger piece
August 13, 2025 at 7:39 AM
Which, to be clear, I am happy to do and I know it can be quite intimidating when you have a lot of them - but it’s quite funny
June 20, 2025 at 6:35 PM
Argyria! The silver deposits under the skin (gets oxidised or somehow fixed by sunlight? Or do all tissues get pigmented?) turning it this silver-blue colour
April 29, 2025 at 11:44 PM
**Not Montelukast, but ranitidine, valsartan, and others
As it turns out, I should have checked my sources. I was thinking of this story www.chemistryworld.com/news/address... and somehow has linked Montelukast in with the affected drugs in my mind. Montelukast remains low risk
Addressing the saga of nitrosamine contamination in drugs
Scientific and regulatory progress is helping minimise the impact of mutagenic impurities
www.chemistryworld.com
April 13, 2025 at 5:29 PM
Your breathy bois are safe! My memory is not

bsky.app/profile/natk...
As it turns out, I should have checked my sources. I was thinking of this story www.chemistryworld.com/news/address... and somehow has linked Montelukast in with the affected drugs in my mind. Montelukast remains low risk
Addressing the saga of nitrosamine contamination in drugs
Scientific and regulatory progress is helping minimise the impact of mutagenic impurities
www.chemistryworld.com
April 13, 2025 at 12:12 AM
To be clear, apart from a specific few old batches of tetracycline, there have been no cases of toxicity from out-of-date medications and the highest risk remains that the medication has degraded and no longer works.
April 13, 2025 at 12:09 AM
As it turns out, I should have checked my sources. I was thinking of this story www.chemistryworld.com/news/address... and somehow has linked Montelukast in with the affected drugs in my mind. Montelukast remains low risk
Addressing the saga of nitrosamine contamination in drugs
Scientific and regulatory progress is helping minimise the impact of mutagenic impurities
www.chemistryworld.com
April 13, 2025 at 12:07 AM
I would guess it comes down to cost again. A few pence per lorry/shipping container vs a few pence per box or blister pack are very different calculations. Would be useful though, particularly for heat where the blister packs are not necessarily good barriers
April 9, 2025 at 12:40 PM