natpernick.bsky.social
@natpernick.bsky.social
My male breast cancer, part 6, discusses my subsequent drug therapy for male breast cancer.

My oncologist recommended a regimen consisting of ribociclib (Kisqali), Lupron and an aromatase inhibitor.

natpernick.substack.com/p/my-male-br...
My male breast cancer, part 6 (drug therapy)
26 December 2025
natpernick.substack.com
December 26, 2025 at 4:31 PM
New Year's Resolution from Michigan's Senator Elissa Slotkin

I am passing along this email from Senator Slotkin without the fundraising requests:

A few thoughts as you work on your New Year’s resolutions.

First, don’t tune out.

natpernick.substack.com/p/new-years-...
New Year's Resolution from Michigan's Senator Elissa Slotkin
23 December 2025
natpernick.substack.com
December 23, 2025 at 10:49 AM
New Year's Resolution from Michigan's Senator Elissa Slotkin

I am passing along this email from Senator Slotkin without the fundraising requests:

A few thoughts as you work on your New Year’s resolutions.

First, don’t tune out.

natpernick.substack.com/p/new-years-...
New Year's Resolution from Michigan's Senator Elissa Slotkin
23 December 2025
natpernick.substack.com
December 23, 2025 at 10:47 AM
This installment is part of my ongoing cancer precursor project, which examines how cancers arise. Part 8 focuses on CNS malignancies (central nervous system).

In Part 8a, we discuss CNS anatomy and histology relevant to CNS tumorigenesis.

natpernick.substack.com/p/cancer-pre...
Cancer precursor project - CNS malignancies, part 8a (anatomy and histology)
22 December 2025
natpernick.substack.com
December 22, 2025 at 10:43 AM
Is a successful Palestine possible in the near future?

In theory, Palestinians should be able to establish a prosperous state that competes economically with Israel.

natpernick.substack.com/p/is-a-succe...
Is a successful Palestine possible in the near future?
19 December 2025
natpernick.substack.com
December 19, 2025 at 9:26 PM
How lung cancer arises, based on complexity theory

I have posted this detailed essay about how lung cancer arises for all 39 types of lung cancer.

natpernick.substack.com/p/how-lung-c...
How lung cancer arises, based on complexity theory
19 December 2025
natpernick.substack.com
December 19, 2025 at 5:55 PM
How cancer arises

I have started a new textbook, hosted on the CCN home page, titled How Cancer Arises. It will cover the pathophysiology of all 1,200 human cancers.
natpernick.substack.com/p/how-cancer...
PathologyOutlines.com
December 18, 2025 at 4:42 PM
Here Are Six Reasons Why Your Worst Fears about American Democracy Won’t Come True in 2026

Chris Bower presents six reasons why your worst fears about American democracy will not come true in 2026. However, complacency will only invite further harm.

natpernick.substack.com/p/here-are-s...
Here Are Six Reasons Why Your Worst Fears about American Democracy Won’t Come True in 2026
16 December 2025
natpernick.substack.com
December 16, 2025 at 10:39 PM
Donald demented, part 2

President Donald J. Trump is demented, deranged and unfit for office. Since my last essay in August 2024, his mental and physical condition appears to have clearly deteriorated.

natpernick.substack.com/p/donald-dem...
Donald demented, part 2
15 December 2025
natpernick.substack.com
December 15, 2025 at 2:26 PM
Voices: I’ve seen how rural hospitals save Utahns’ lives. Cuts to Medicaid threaten their very existence.

By Rachel Pernick, For The Salt Lake Tribune, Dec. 12, 2025
Voices: I’ve seen how rural hospitals save Utahns’ lives. Cuts to Medicaid threaten their very existence.
"We do not close roads for being less-frequently travelled," writes medical student Rachel Pernick in an op-ed. "Hospitals, like roads, constitute critical infrastructure which allow for people to liv...
www.sltrib.com
December 14, 2025 at 1:49 PM
Making important decisions

I am often struck by how intelligent people can focus on the wrong factors when making important decisions.

natpernick.substack.com/p/making-imp...
Making important decisions
14 December 2025
natpernick.substack.com
December 14, 2025 at 1:26 PM
Palestinian self-genocide

I am a genuine friend of the Palestinian people. But real friendship does not mean excusing harmful behavior. Palestinians will remain politically doomed in the Middle East until they abandon what I call their “self-genocide”.

natpernick.substack.com/p/palestinia...
Palestinian self-genocide
10 December 2025
natpernick.substack.com
December 10, 2025 at 7:14 AM
How Can Outrageous CEO Pay be Stopped?

I’m sharing this essay by Robert Reich in which he highlights the problem of excessive CEO pay. He urges us to contact our members of Congress and advocate for the Tax Excessive CEO Pay Act.

natpernick.substack.com/p/how-can-ou...
How Can Outrageous CEO Pay be Stopped?
9 December 2025
natpernick.substack.com
December 9, 2025 at 9:36 AM
We should ignore most rulings of the Roberts court regarding Trump

The Supreme Court has abandoned the practices that once gave it credibility, namely consistency, transparency and real deliberation.

natpernick.substack.com/p/we-should-...
We should ignore most rulings of the Roberts court regarding Trump
8 December 2025
natpernick.substack.com
December 8, 2025 at 10:48 PM
Pearl Harbor day

It has now been 84 years since the Japanese attacked Pearl Harbor, Oahu, Hawaii.

Historian Heather Cox Richardson has a wonderful essay about the attack.

natpernick.substack.com/p/pearl-harb...
Pearl Harbor day
7 December 2025
natpernick.substack.com
December 7, 2025 at 10:30 AM
Why and how I try to boycott the billionaires

The U.S. has become a government of, by and for the billionaires. Much of our federal policy is based on the inappropriate control by the wealthy of government, intended to satisfy their insatiable greed.

natpernick.substack.com/p/why-and-ho...
Why and how I try to boycott the billionaires
5 December 2025
natpernick.substack.com
December 6, 2025 at 12:52 AM
Tax Excessive CEO Pay

I am a strong advocate of capitalism. What I do not support is the pervasive greed that has taken hold across corporate America.

That’s why I support the Patriotic Millionaires in their efforts to rein in excessive CEO compensation.

natpernick.substack.com/p/tax-excess...
Tax Excessive CEO Pay
3 December 2025
natpernick.substack.com
December 3, 2025 at 1:21 PM
Relaunch of the Detroit College Promise

We have relaunched the Detroit College Promise, a 501(c)(3) nonprofit that I started in 2008 in memory of my parents, Larry and Anne Pernick, who attended DPS schools.

natpernick.substack.com/p/relaunch-o...
Relaunch of the Detroit College Promise
2 December 2025
natpernick.substack.com
December 2, 2025 at 1:56 PM
The importance of the rule of law in the United States

As a practicing attorney for 20 years, I believe the rule of law is essential to life in the United States.

natpernick.substack.com/p/the-import...
The importance of the rule of law in the United States
1 December 2025
natpernick.substack.com
December 1, 2025 at 6:36 PM
5 Questions I’d Never Leave My Annual Preventive Visit Without Asking

I thought this essay was useful. Here are the questions, with more details at the link:

1. What preventative care screenings or blood tests should I schedule?

natpernick.substack.com/p/5-question...
5 Questions I’d Never Leave My Annual Preventive Visit Without Asking
28 November 2025
natpernick.substack.com
November 28, 2025 at 2:47 PM
Thoughts for Thanksgiving, 2025

Heather Cox Richardson describes the history of the holiday:

Thanksgiving is the quintessential American holiday…but not for the reasons we generally remember.

natpernick.substack.com/p/thoughts-f...
Thoughts for Thanksgiving, 2025
27 November 2025
natpernick.substack.com
November 27, 2025 at 5:39 PM
Living a principled life

If we want to create a better world, we need to change our behavior and strive to live a principled life, where our actions align with our values. Perfection isn’t required, but a sincere effort is.

natpernick.substack.com/p/living-a-p...
Living a principled life
26 November 2025
natpernick.substack.com
November 26, 2025 at 1:11 PM
Support the "We Ain't Buying It" campaign

Join the We Ain’t Buying It campaign and take action over Thanksgiving to pressure companies to stop colluding with the Trump administration and enabling their authoritarian overreach.

natpernick.substack.com/p/support-th...
Support the "We Ain't Buying It" campaign
25 November 2025
natpernick.substack.com
November 25, 2025 at 11:25 AM
Keep your comments short in meetings

I received a helpful suggestion for meetings and wanted to share it. Since we all prefer shorter meetings, we should try to keep our comments to about 30 seconds, or 30 seconds per topic.

natpernick.substack.com/p/keep-your-...?
Keep your comments short in meetings
24 November 2025
natpernick.substack.com
November 24, 2025 at 11:41 PM
My vision for Palestinians

Palestinians must take the lead now in defining the shape and priorities of a future Palestinian state. If they do not, others will define it for them and the outcome will likely be far from what Palestinians want.

natpernick.substack.com/p/my-vision-...
My vision for Palestinians
24 November 2025
natpernick.substack.com
November 24, 2025 at 3:16 PM