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Natural Product Reports @natprodreports.rsc.org · 2d

⏳There is just under 2 weeks left for you to nominate a rising star in natural product research for the 2026 @natprodreports.rsc.org Emerging Investigator Lectureship! #chemsky #secmet #synbio #naturalproducts

📅Nominations close 19 October

Details on how to nominate🔽
www.rsc.org/standards-an...

Technological developments driving industrial natural product discovery

Natural Product Reports @natprodreports.rsc.org · 5d

Don't miss in our latest issue this review, part of our Industrial Perspective themed collection, on the technological developments driving industrial natural product discovery by Nick Allenby & co. at the University of Sunderland #natprod

Check it out in full here👇
pubs.rsc.org/en/content/a...

Covering: up to 2025 Bacterial natural products have long been the foundation for many therapeutic agents. However, traditional culture-based approaches to discovering these products have been deprioritised...

Natural products targeting the metabolism of amino acids: from discovery to synthetic development

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Natural Product Reports @natprodreports.rsc.org · 7d

Check out this review by Jaehoon Sim et al. from Kyung Hee University in our latest issue highlighting the recent developments in the discovery to synthetic development of natural products targeting the metabolism of amino acids #secmet #natprod

Read in full here🔽
pubs.rsc.org/en/content/a...

Covering: up to 2025 Amino acids constitute the essential components of biological systems. Over the recent years, there has been a growing interest in exploring amino acid metabolism as a source of novel...

Recent advances in discovery and biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPP)-derived lipopeptides

Natural Product Reports @natprodreports.rsc.org · 9d

🔓Take a look in our latest issue at a #OpenAccess review covering the recent advances in the discovery and biosynthesis of RiPP-derived lipopeptides by Shumpei Asamizu #secmet #natprod

📍Kobe University

Covering: This review summarizes recent advances in the discovery, biosynthesis, and bioactivity of RiPP-derived lipopeptides, covering studies published up to 2024. Ribosomally synthesized and…

Trends in metabolite discovery from Actinomycetes

Natural Product Reports @natprodreports.rsc.org · 12d

Be sure to read this review, part of our Industrial Perspective themed collection, by Stefano Donadio & co. from NAICONS Srl discussing the trends in metabolite discovery from Actinomycetes #secmet #natprod

Find it in full below👇

Covering: 2013 to 2023 In this review, we analyzed the scientific literature of the period 2013–2023 that reported novel specialized metabolites from the Actinomycetes, one of the most prolific…

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Natural Product Reports @natprodreports.rsc.org · 14d

ICYMI: Nominations for the 2026 @natprodreports.rsc.org Emerging Investigator Lectureship are currently open! #chemsky #secmet #naturalproducts #synbio 🧪

⌛Deadline for nominations is 19 October 2025

Details on how to nominate can be found on our website here▶️rsc.li/npr-lectureship

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Natural Product Reports @natprodreports.rsc.org · 16d

Our latest issue has an inside front cover! Don't miss the review behind it from Changsheng Wu et al. at Shandong University looking at recent use of NMR-based metabolomics to explore microbial natural products #natprod

Check out the full article on our website🔽
pubs.rsc.org/en/content/a...

The chemical and biological properties of natural resorcylic acid lactones

Natural Product Reports @natprodreports.rsc.org · 21d

📢Our latest issue is now online!

🔓Check out the #OpenAccess review behind the front cover by Xiaofei Shang, Xiaolou Miao, Xiuhui Li, Xiaorong Yang et al. at the Chinese Academy of Agricultural Sciences looking at natural products use in antiparasitic drug discovery

pubs.rsc.org/en/content/a...

Natural Product Reports @natprodreports.rsc.org · 25d

We are delighted to sponsor the Natural Products in the 'Omics Era' symposium at @pacifichem.bsky.social!

Keynote speakers include Helen Woolner @vicuniwgtn.bsky.social whose research focuses on bioactive natural products from marine bacteria & fungi #ORG018

📅19-20 December 2025
🔗pacifichem.org

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Natural Product Reports @natprodreports.rsc.org · 27d

Be sure to read in our latest issue this review by Hanli Ruan et al. from Huazhong University of Science & Technology discussing the chemical and biological properties of natural resorcylic acid lactones #naturalproducts

Find their full article below👇

Covering: 1953 to Feb 2025 Resorcylic acid lactones (RALs) represent a significant category of polyketides characterized by a β-resorcylate unit embedded in a macrolactone ring. Since the discovery…

Recent insights into the biosynthesis and biological activities of the peptide-derived redox cofactor mycofactocin

Natural Product Reports @natprodreports.rsc.org · 29d

🔓Take a look at a #OpenAccess review by Gerald Lackner & co. covering recent insights into the biosynthesis and biological activities of the peptide-derived redox cofactor mycofactocin #secmet #natprod

📍 @lacknerlab.bsky.social @unibayreuth.bsky.social @uni-jena.de

Covering: 2011 to 2025 The importance of redox cofactors like nicotinamide adenine dinucleotide or flavin adenine dinucleotide as cofactors for enzymatic reactions in living organisms is widely…

A personal selection of 32 recent papers is presented covering various aspects of current developments in bioorganic chemistry and novel natural products such as hypbeaone A from Hypericum beanii.

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Natural Product Reports @natprodreports.rsc.org · Sep 5

🔥Be sure to read the latest Hot Off the Press article by Robert Hill &
@andysuth14.bsky.social from @uofgchem.bsky.social on their selection of 32 recent papers covering the latest research in bioorganic chemistry & novel natural products #naturalproducts

Find it here🔽

Hot off the Press

Recent highlights of the total synthesis of cyclic peptide natural products

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Natural Product Reports @natprodreports.rsc.org · Sep 3

📢Do you know a rising star in natural product research?

We are pleased to announce nominations for the 2026
@natprodreports.rsc.org Emerging Investigator Lectureship are open! #secmet #natprod

📅Nominations close 19 October

Visit our webpage for details on how to nominate🔽
rsc.li/npr-lectureship

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Natural Product Reports @natprodreports.rsc.org · Sep 1

🔓Don't miss this review, part of our Synergy of Synthetic Methodology & Natural Product Synthesis collection, by Takayuki Doi et al. at Tohoku University focused on some recent highlights of the total synthesis of cyclic peptide natural products #natprod

Check it out👇

Covering: 2020 to 2022 This review described the total synthesis of naturally occurring cyclic peptides with unique structures covering 2020 to 2022, i.e., darobactin A, pyritide A2, decatransin,…

Prenylated bacterial natural products: occurrence, chemical diversity, biosynthesis and bioactivity

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Natural Product Reports @natprodreports.rsc.org · Aug 28

Check out a review by Lei Li et al. from Shanghai Jiao Tong University in our latest issue looking at the chemical diversity, biosynthesis and bioactivity of prenylated bacterial natural products #secmet #naturalproducts

Read the full article on our website🔽

Covering: 2000 to 2024 Prenylated bacterial natural products (NPs), catalyzed by cluster-situated prenyltransferases (PTs), exhibit large structural diversity and broad biological activities and have…

Discovery, structure revision, synthesis, and application of all known and even unknown securingine alkaloids

Natural Product Reports @natprodreports.rsc.org · Aug 26

Take a look in our latest issue at a Highlight by Chungwoo Lee & Sunkyu Han discussing the discovery, structure revision, synthesis and application of all known and even unknown securingine alkaloids #naturalproducts

📍KAIST

Covering: up to 2025 Natural product-based research encompasses the discovery, structure elucidation, biosynthesis, synthesis, and application of naturally occurring secondary metabolites.…

Advances in the discovery and study of Trichoderma natural products for biological control applications

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Natural Product Reports @natprodreports.rsc.org · Aug 21

🔓Read this #OpenAccess article from Sophie Jin & Fabrizio Alberti @albertilab.bsky.social @warwicklifesci.bsky.social in our latest issue discussing the advances in the discovery and study of Trichoderma natural products #secmet #natprod

Find the full review below👇

Covering: up to 2025 Reducing the prevalence of phytopathogens and their impact on crops is essential to reach sustainable agriculture goals. Synthetic pesticides have been commonly used to control…

Remodeling of ribosomally synthesized peptide backbones based on posttranslational modifications

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Natural Product Reports @natprodreports.rsc.org · Aug 19

Don't miss in our latest issue this review, part of our 40th anniversary collection, from Wen Liu & co. at Shanghai Institute of Organic Chemistry looking at the PTM enzymes that remodel RiPP backbones #secmet #naturalproducts

Check it out here🔽

Covering: 2013–2024 Benefiting significantly from recent advances in genome mining, ribosomally synthesized and posttranslationally modified peptide (RiPP) natural products have emerged as a source…

Natural Product Reports @natprodreports.rsc.org · Aug 13

📢Our latest issue is now online!

🔓Check out the #OpenAcces article behind the cover from Hendrik Luesch, Yousong Ding & co. @ufresearch.bsky.social on synthetic biology strategies for cyanobacterial heterologous expression of natural products #syntheticbiology #secmet

pubs.rsc.org/en/content/a...

Recent advances in the chemistry and biology of plant oxylipin hormones

Natural Product Reports @natprodreports.rsc.org · Aug 7

🔓Be sure to read this #OpenAccess review from Minoru Ueda et al. at Tohoku University in our latest issue discussing the recent advances in the chemistry and biology of plant oxylipin hormones

Find their article in full here👇

Jasmonates, including jasmonic acid (JA) and its derivatives, are lipid-based signaling molecules critical for plant growth, development, and defense. Among these, jasmonoyl-l-isoleucine (JA-Ile) has…

Unlocking marine treasures: isolation and mining strategies of natural products from sponge-associated bacteria

Natural Product Reports @natprodreports.rsc.org · Aug 5

🔓Don't miss a #OpenAccess review in our latest issue by Jae Kyu Lim, Eung-Soo Kim & co at KIOST & Inha University looking at the isolation and mining strategies of natural products from sponge-associated bacteria #secmet #naturalproducts

Check it out below🔽

Covering: 2019 to early 2025 Marine sponges form unique ecosystems through symbiosis with diverse microbial communities, producing natural products including bioactive compounds. This review…

The bisintercalator family of nonribosomal peptides: structural diversity and biosynthetic mechanism

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Natural Product Reports @natprodreports.rsc.org · Jul 31

Check out a review by Xinjie Shi from Zhejiang University in our latest issue discussing the structural diversity and biosynthetic mechanism of the bisintercalator family of nonribosomal peptides #secmet #naturalproducts

Read it in full on our website👇

Covering: up to February 2025 Among the numerous bioactive microbial natural products, a subset of nonribosomal peptides derived from actinobacteria is characterized by their C2-symmetric macrocyclic…

Modulators of the ubiquitin–proteasome system from natural products: chemical structures and their potential for drug discovery

Natural Product Reports @natprodreports.rsc.org · Jul 29

Take a look in our latest issue at this review from Yuki Hitora & Sachiko Tsukamoto looking at the chemical structures of natural product modulators of the ubiquitin–proteasome system and their potential in drug discovery

📍Kumamoto University

Covering: up to 2024 The ubiquitin–proteasome system (UPS) plays a key role in regulating intracellular protein degradation and maintaining cellular homeostasis. Within the UPS, target proteins are…