Xiaowen and I have had great support on this project from the Parkinson's Foundation, NINDS, and ASAP!
@asapresearch.bsky.social

Xiaowen found that parkinsonian mice treated with a dopamine agonist medication developed impulsive behavior on a delay discounting task, similar to what is seen in Parkinson's. She went on to show that inhibition of striatal indirect pathway neurons is a key mechanism.