Filip Nemcko
@nemcko.bsky.social
Scientist @arcinstitute
Ex–@stark_lab, @IMPvienna, @viennabiocenter
Ex–@stark_lab, @IMPvienna, @viennabiocenter
Thank you Christa! 😊
December 30, 2025 at 8:05 AM
Thank you Christa! 😊
Read the full story in our preprint! 👇
biorxiv.org/content/10.6...
Excited to share this work with my co-first author Kevin Sabath - a fantastic collaboration between the
@alex-stark.bsky.social and @plaschkalab.bsky.social labs! 🤝🧪
biorxiv.org/content/10.6...
Excited to share this work with my co-first author Kevin Sabath - a fantastic collaboration between the
@alex-stark.bsky.social and @plaschkalab.bsky.social labs! 🤝🧪
Activator-promoter compatibility in mammals: a CpG-Island-specific co-activator directly bridges transcription factors to TFIID
Transcription from CpG island (CGI) promoters controls the expression of two-thirds of mammalian genes, yet despite their prevalence, it remains unknown whether CGI-specific co-activators with intrins...
biorxiv.org
December 29, 2025 at 7:30 PM
Read the full story in our preprint! 👇
biorxiv.org/content/10.6...
Excited to share this work with my co-first author Kevin Sabath - a fantastic collaboration between the
@alex-stark.bsky.social and @plaschkalab.bsky.social labs! 🤝🧪
biorxiv.org/content/10.6...
Excited to share this work with my co-first author Kevin Sabath - a fantastic collaboration between the
@alex-stark.bsky.social and @plaschkalab.bsky.social labs! 🤝🧪
Using Hcfc1 as a model, we show it functions as a molecular bridge: it connects CGI-bound TFs directly to TFIID. This recruitment overcomes a rate-limiting step unique to CGI promoters, enabling transcription initiation. 🧬🌉
December 29, 2025 at 7:30 PM
Using Hcfc1 as a model, we show it functions as a molecular bridge: it connects CGI-bound TFs directly to TFIID. This recruitment overcomes a rate-limiting step unique to CGI promoters, enabling transcription initiation. 🧬🌉
Enjoyed reading and writing a perspective on your study, congrats!
July 5, 2025 at 7:22 AM
Enjoyed reading and writing a perspective on your study, congrats!
Huge congratulations, Victoria!
June 4, 2025 at 7:33 AM
Huge congratulations, Victoria!
congratulations Christa! 🥳
December 3, 2024 at 12:07 PM
congratulations Christa! 🥳