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Nikki Link @nikkilink.bsky.social · Jul 10

Congrats Nicole and all contributing authors!

Nikki Link @nikkilink.bsky.social · Jul 10

Human SNW1 can rescue loss of fly Bx42. We are now testing variants to determine how they cause microcephaly.

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Nikki Link @nikkilink.bsky.social · Jul 10

New neurodevelopmental disorder gene SNW1/Bx42. In flies, we show that loss of Bx42 causes reduced brain size and reduced numbers of neural stem cells that divide less.

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Nikki Link @nikkilink.bsky.social · Jul 10

Nicole's collaborative paper accepted. Be on the lookout for the final version at the Journal of Clinical Investigation. www.jci.org/articles/vie...

JCI - Mutations in spliceosomal gene SNW1 cause neurodevelopment disorders with microcephaly

www.jci.org

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Nikki Link @nikkilink.bsky.social · Jul 10

www.eneuro.org/content/12/5...

Loss of Neuronal Imp Contributes to Seizure Behavior through Syndecan Function

Seizures affect a large proportion of the global population and occur due to abnormal neuronal activity in the brain. Unfortunately, widespread genetic and phenotypic heterogeneity contributes to insu...

www.eneuro.org

Nikki Link @nikkilink.bsky.social · Jul 10

eNeuro featured Paula's brain and publication in their Blog. Take a look. blog.eneuro.org/2025/06/snap...

eNeuro BlogSnapshots in Neuroscience: Larval fruit fly brain

blog.eneuro.org

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Nikki Link @nikkilink.bsky.social · Jul 8

Excited for Summer Science Day!

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Reposted by Nikki Link

SfN Journals @sfnjournals.bsky.social · Jul 3

#SnapshotsinNeuroscience: Larval fruit fly brain
This image from Roy and Link shows neuronal expression of seizure-associated proteins in a third-instar larval fruit fly brain. Image credit: Paula Roy
https://blog.eneuro.org/2025/06/snapshots_larval_drosophila_brain

The image was captured on a Zeiss 710 confocal microscope at 20x using endogenously tagged Sdc-GFP to highlight Sdc (green), ElaV/Alexa Fluor 647 to stain neurons (cyan), and Imp/Rhodamine RedX to show Imp protein (yellow). Image by Paula Roy.

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Reposted by Nikki Link

FlyBase @flybase.bsky.social · Jun 25

MassLive.com recently interviewed several Harvard FlyBase people and wrote this news article about the importance of FlyBase: tinyurl.com/4chpts9f

Why a database of bug genes could be one of Trump’s most devastating cuts at Harvard

FlyBase, the world's only fruit fly database, is in the crosshairs of Trump's attack on Harvard. Here's why it could matter for your health.

tinyurl.com

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Nikki Link @nikkilink.bsky.social · Jun 14

Participating in study section was a really great experience.

Nikki Link @nikkilink.bsky.social · Jun 11

It was great to be part of this project. The film students at SLCC made a fantastic documentary!

Genetics Society of America @genetics-gsa.bsky.social · Jun 10

Could fruit flies be the key to decoding rare human diseases? 🪰 🧬 Watch researchers at @nikkilink.bsky.social‬'s Link Lab & @clementychow.bsky.social‬'s Chow Lab use these tiny models to uncover new insights & potential treatments for rare conditions: buff.ly/xKXEbCS 🎬

Fruit Flies: Decoding Rare Diseases

"Fruit Flies: Decoding Rare Diseases" follows two teams of researchers from the Link Lab and Chow Lab as they study rare human diseases in fruit flies, seeki...

buff.ly

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Nikki Link @nikkilink.bsky.social · May 17

Congrats Nicole!

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Reposted by Nikki Link

Clement Chow @clementychow.bsky.social · May 3

Repost w/ correct link!
The Dept of Human Genetics at the Univeristy of Utah is hosting a Rising Stars in Genetics & Genomics postdoc symposium. We are looking to feature postdocs doing cool science! Please self nominate or nominate an excellent postdoc! #ASHGtrainees docs.google.com/forms/d/e/1F...