Nick Lue
@nlue8.bsky.social
Postdoc at Nogales Lab | PhD in chemical biology at Brian Liau Lab, Harvard | UC Berkeley '17 | transcription, chromatin, graphic design | he/him
Reposted by Nick Lue
Everyone in academia should read this piece about our dear, brilliant colleague @durba.bsky.social
www.thecrimson.com/article/2025...
www.thecrimson.com/article/2025...
A Surprise Tenure Denial in Harvard’s Gender Studies Program Leaves Some Faculty Shaken | News | The Harvard Crimson
Durba Mitra’s colleagues thought she was a near-perfect tenure candidate. When her bid was shot down in June, they were left questioning the process.
www.thecrimson.com
September 22, 2025 at 3:15 PM
Everyone in academia should read this piece about our dear, brilliant colleague @durba.bsky.social
www.thecrimson.com/article/2025...
www.thecrimson.com/article/2025...
Our work on RECQL5 transcriptional regulation is now out in journal form! A huge shoutout to my co-lead @alfredo0712.bsky.social and everyone else in the @nogaleslab.bsky.social!
Our work, co-led by @alfredo0712.bsky.social and @nlue8.bsky.social is out in @natsmb.nature.com Shout out to coauthors P.Grob, B. Kaeser, J.Fang, and S. Kassube for their contributions and thanks to the reviewers for the suggestions that led to the final work.
www.nature.com/articles/s41...
Structural insights into transcriptional regulation by the helicase RECQL5 - Nature Structural & Molecular Biology
Florez Ariza and Lue et al. use cryo-electron microscopy to investigate how the RECQL5 helicase regulates transcription. Their structural findings suggest that RECQL5 can modulate RNA polymerase II’s ...
www.nature.com
July 8, 2025 at 5:26 PM
Our work on RECQL5 transcriptional regulation is now out in journal form! A huge shoutout to my co-lead @alfredo0712.bsky.social and everyone else in the @nogaleslab.bsky.social!
Reposted by Nick Lue
Today in @nature.com we share our back-to-back stories with Ning Zheng’s lab revealing chemical-genetic convergence between a molecular glue degrader & E3 ligase cancer mutations. 1/5
February 12, 2025 at 4:20 PM
Today in @nature.com we share our back-to-back stories with Ning Zheng’s lab revealing chemical-genetic convergence between a molecular glue degrader & E3 ligase cancer mutations. 1/5
Is it a bird? Is it a plane? No... it's RECQL5 bound to the Pol II elongation complex!!
Excited to share this work, which is my first foray into cryo-EM 🔬 It's been awesome working with @alfredo0712.bsky.social, an incredible scientist and colleague.
Excited to share this work, which is my first foray into cryo-EM 🔬 It's been awesome working with @alfredo0712.bsky.social, an incredible scientist and colleague.
Check out our lab’s latest work on the regulation of transcription by RECQL5 helicase! This work was co-led by @alfredo0712.bsky.social and @nlue8.bsky.social, with contributions from Patricia Grob, Ben Kaeser, Jie Fang, and Susanne Kassube. 1/7
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Structural insights into transcriptional regulation by the helicase RECQL5
Transcription and its regulation pose a major challenge for genome stability. The helicase RECQL5 has been proposed as an important factor to help safeguard the genome, and is the only member of the h...
www.biorxiv.org
January 31, 2025 at 6:22 PM
Is it a bird? Is it a plane? No... it's RECQL5 bound to the Pol II elongation complex!!
Excited to share this work, which is my first foray into cryo-EM 🔬 It's been awesome working with @alfredo0712.bsky.social, an incredible scientist and colleague.
Excited to share this work, which is my first foray into cryo-EM 🔬 It's been awesome working with @alfredo0712.bsky.social, an incredible scientist and colleague.