AS-eligible patients with APF at RP demonstrate differences in gene expression when compared to those without APF. We established that multiple existing genomic classifiers not previously studied in t...

Krambeck pointed to the growing importance of medical management in stone disease prevention.

Dr. Ziho Lee tackles a challenging vesicourethral anastomotic stricture, using a dual robotic-perineal approach to restore function in a post-prostatectomy patient.

Introduction and Objectives: Managing nephrolithiasis during pregnancy requires collaboration between obstetricians and urologists. When surgical intervention is needed, ureteroscopy (URS) is a safe and effective; however, limited data exist on obstetric (OB) management and complications of URS during pregnancy. This multicenter study aimed to clarify OB practice patterns and complications of URS in pregnant patients. Methods: A multicenter retrospective review of pregnant patients who underwent URS with fellowship-trained endourologists at seven institutions from 2015 to 2024 was performed. We recorded patient demographics, indications for URS, preoperative workup, intraoperative details, perioperative OB involvement, fetal monitoring (FM) practices, and postoperative OB complications within 30 days. Results: We identified 72 cases of URS during pregnancy. Mean maternal age was 30 years, and mean gestational age was 23.5 weeks. Preoperative imaging was performed in all cases, with ultrasound used in 70/72 (97%). No intraoperative complications were noted. OB involvement and FM varied among institutions—one site required perioperative OB presence with FM, five sites performed FM case-by-case, and one site required pre- and postoperative nonstress tests (NST). FM was done in 11/72 cases, while intraoperative FM was performed in 16/72 cases. OB was present in 13/72 cases. OB complications occurred in eight cases. There were no cases of preterm labor in the immediate perioperative; however, three cases had postoperative admissions with spontaneously resolving contractions and abnormal NST. The two cases of preterm labor requiring C-section at 27 weeks were linked to OB comorbidities. Conclusions: URS is safe in pregnancy in the care of urologists who are experienced in stone disease. OB management and FM during URS are heterogeneous across institutions. In this multicenter series, there were no cases of preterm labor. Cases of early contractions and abnormal NST resolved spontaneously. Standardization of OB practice patterns during URS could be beneficial and incorporated in further guideline development.

Dr. Joshua Meeks discusses evolving treatments for BCG-unresponsive bladder cancer, comparing FDA-approved options and advocating for robust clinical trials.

Northwestern Medicine investigators have discovered a new combination approach that may improve the efficacy of MYC inhibitor drugs for treating aggressive and treatment-resistant cancers, according t...

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The course addresses "unicorn cases" in the upper tract—unique and challenging situations lacking established guidelines or literature.

“I thought prostate cancer was something older men mainly dealt with,” Terrance Jones told The Post.

Amy E. Krambeck, MD, discusses how to define success and how to determine the optimal timing for adding on a new partner.

“It's going to be an important time for US urologists to identify that this is becoming the standard of care," says Joshua J. Meeks, MD, PhD.

“The takeaway is that on a population level, on a health care system perspective, it's more cost-effective and safer to do transperineal prostate biopsy,” says Mitchell M. Huang, MD.

Dr. Amy Krambeck shares how HoLEP resolved LUTS chronic UTIs and an obstructed prosthetic urethra in a patient after aquablation failed, removing 189g of obstructive prostate tissue.

Amir S. Patel, MD, discusses interim findings from a randomized controlled trial of onabotulinumtoxinA injection at the time of HoLEP vs standard treatment.