grant proposals are fighting an uphill battle against reviewers' visceral concept of an acceptable sample size. at least twice I've had reviewers ignore the power analysis and say it just seemed too small.

sure, but if you rely on that grant to keep a roof over your head, I think you're entitled to some concern when reviews are delayed

I don't, but it's also not hard to game pre-registration

46% of preadolescent girls had "misaligned" biological sex and gender?

"no garbage"

I guess this is a different conversation but we are assuming here that score is tightly related to quality. I am less confident of this each time I sit on study section

kind of a bold claim

Factor 3: Expertise and Resources

I just got an "Additional expertise needed" because one consultant is off-site. in the year of our lord 2025. no other comments. :)

the link takes me to the wrong place! do you have another?

really cool!!! love to see the convergence across PET / genes / fMRI. please please consider making the .niis / statistical maps from figs 3-5 downloadable!! curious to see how closely the activation pattern you report overlaps with other CUD studies 😁

high-dose stimulants lead to psychosis -- basically, if you keep turning up the "salience" volume eventually everything seems salient and the brain scrambles to explain it?

this paper was such a joy to read. in addition to the very thorough treatment of the data I love how densely-referenced the intro is; I think I learned something from every sentence! one passing thought about the salience boost -- I wonder if that's the mechanism by which (cont)

I'm curious if some journals are already implementing this. I have 1 paper under re-review and got 3 reviews. R3 was clearly written by AI, but I assumed someone got invited to review and used AI. I checked the researchsquare timeline and only 2 reviewers ever agreed.

thank you, I just dipped my toe in (louvain) and will be taking it back out. sbm = stochastic block model?

super cool -- thought this might be of interest if you hadn't seen it already: elifesciences.org/articles/71846

thank you!! reassuring that this is business as usual!

Congrats, very cool finding and wow, what an effort!! I bet we could use tms + fmri to test this circuit in humans 🧐